Development Level

Tbio 449 | 11,651
Tchem 62 | 1,388
Tdark 61 | 6,593
Tclin 21 | 612

Collection

RFA-RM-18-021 11 | 328
Kinase: IDG Consortium (Target... 6 | 125
GPCR: IDG Consortium (Targets) 3 | 126
Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, complete... 41 | 979
embryonic lethality prior to t... 14 | 278
preweaning lethality, incomple... 13 | 499
decreased total body fat amoun... 11 | 207
abnormal seminal vesicle morph... 10 | 114
decreased vertical activity 10 | 208
embryonic lethality prior to o... 10 | 239
enlarged heart 10 | 210
abnormal behavior 9 | 298
abnormal embryo size 9 | 220
abnormal heart morphology 9 | 162
increased circulating alkaline... 9 | 122
abnormal kidney morphology 8 | 65
decreased body weight 8 | 161
decreased mean corpuscular vol... 8 | 79
increased or absent threshold ... 8 | 101
decreased leukocyte cell numbe... 7 | 73
increased lean body mass 7 | 172
small superior vagus ganglion 7 | 74
abnormal bone structure 6 | 187
abnormal testis morphology 6 | 43
decreased circulating calcium ... 6 | 36
decreased circulating glucose ... 6 | 126
decreased circulating insulin ... 6 | 76
decreased hemoglobin content 6 | 68
decreased lymphocyte cell numb... 6 | 83
increased bone mineral density 6 | 72
short tibia 6 | 97
abnormal epididymis morphology 5 | 42
decreased bone mineral density 5 | 126
decreased circulating choleste... 5 | 93
decreased circulating triglyce... 5 | 79
decreased mean corpuscular hem... 5 | 50
hydrometra 5 | 53
hypoactivity 5 | 132
improved glucose tolerance 5 | 79
increased bone mineral content 5 | 108
increased monocyte cell number 5 | 63
increased startle reflex 5 | 112
increased total body fat amoun... 5 | 134
small testis 5 | 58
abnormal coat-hair pigmentatio... 4 | 64
abnormal gait 4 | 69
abnormal lens morphology 4 | 81
abnormal retina morphology 4 | 71
decreased circulating LDL chol... 4 | 38
decreased circulating serum al... 4 | 82
decreased erythrocyte cell num... 4 | 62
decreased prepulse inhibition 4 | 82
edema 4 | 59
enlarged epididymis 4 | 31
increased circulating choleste... 4 | 66
increased circulating triglyce... 4 | 42
increased neutrophil cell numb... 4 | 46
prenatal lethality prior to he... 4 | 87
thrombocytopenia 4 | 56
abnormal embryo turning 3 | 31
abnormal joint morphology 3 | 23
abnormal sleep behavior 3 | 70
brachydactyly 3 | 19
cardiovascular system phenotyp... 3 | 36
cataract 3 | 92
decreased body length 3 | 101
decreased circulating bilirubi... 3 | 19
decreased circulating fructosa... 3 | 30
decreased startle reflex 3 | 75
embryonic growth retardation 3 | 106
enlarged kidney 3 | 14
enlarged lymph nodes 3 | 37
female infertility 3 | 60
increased blood urea nitrogen ... 3 | 48
increased circulating HDL chol... 3 | 80
increased circulating creatini... 3 | 38
increased circulating serum al... 3 | 22
increased erythrocyte cell num... 3 | 39
increased fasted circulating g... 3 | 76
increased heart rate 3 | 23
increased mean corpuscular hem... 3 | 96
increased mean corpuscular vol... 3 | 92
male infertility 3 | 123
small adrenal glands 3 | 16
syndactyly 3 | 23
thrombocytosis 3 | 27
abnormal locomotor behavior 2 | 24
abnormal skin coloration 2 | 25
abnormal skin morphology 2 | 50
decreased bone mineral content 2 | 151
decreased caudal vertebrae num... 2 | 53
decreased circulating HDL chol... 2 | 68
decreased circulating free fat... 2 | 31
decreased circulating total pr... 2 | 49
decreased eosinophil cell numb... 2 | 24
impaired glucose tolerance 2 | 75
increased body weight 2 | 25
increased circulating aspartat... 2 | 15
increased circulating calcium ... 2 | 34
increased circulating potassiu... 2 | 29
increased heart weight 2 | 62
increased prepulse inhibition 2 | 32
pallor 2 | 34

Disease

Carcinoma 410 | 11,493
ovarian cancer 348 | 8,520
osteosarcoma 317 | 7,950
psoriasis 237 | 6,694
glioblastoma 222 | 5,792
medulloblastoma, large-cell 222 | 6,241
lung cancer 192 | 4,740
atypical teratoid / rhabdoid tumor 180 | 5,112
ependymoma 164 | 4,679
malignant mesothelioma 146 | 3,232
Breast cancer 144 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 135 | 3,291
adult high grade glioma 133 | 3,801
group 3 medulloblastoma 133 | 4,104
invasive ductal carcinoma 118 | 2,951
Cancer 113 | 2,499
Kidney cancer 112 | 2,613
non-small cell lung cancer 111 | 2,890
lung carcinoma 108 | 2,843
Astrocytoma, Pilocytic 107 | 3,081
oligodendroglioma 107 | 2,850
intraductal papillary-mucinous carcinoma (IPMC) 106 | 2,989
lung adenocarcinoma 103 | 2,716
subependymal giant cell astrocytoma 102 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 101 | 2,955
pancreatic cancer 99 | 2,398
astrocytic glioma 98 | 2,597
tuberculosis 95 | 2,010
primitive neuroectodermal tumor 94 | 3,035
interstitial cystitis 93 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 90 | 1,962
Autosomal recessive predisposition 78 | 1,442
group 4 medulloblastoma 72 | 1,855
diabetes mellitus 69 | 1,728
ulcerative colitis 68 | 1,819
Pick disease 66 | 1,894
astrocytoma 66 | 1,146
juvenile dermatomyositis 66 | 1,187
pituitary cancer 63 | 1,972
Multiple myeloma 59 | 1,332
adrenocortical carcinoma 59 | 1,428
breast carcinoma 58 | 1,638
colon cancer 57 | 1,478
cystic fibrosis 57 | 1,696
ductal carcinoma in situ 57 | 1,745
Rheumatoid arthritis 55 | 1,191
acute quadriplegic myopathy 53 | 1,158
Intellectual disability 51 | 1,016
spina bifida 51 | 1,074
dermatomyositis 50 | 966
Atopic dermatitis 48 | 952
cutaneous lupus erythematosus 47 | 1,057
Schizophrenia 45 | 1,160
pediatric high grade glioma 43 | 1,064
Epilepsy 42 | 792
active ulcerative colitis 42 | 764
primary Sjogren syndrome 42 | 735
Liver Cirrhosis, Experimental 38 | 769
active Crohn's disease 37 | 922
nasopharyngeal carcinoma 37 | 1,058
Alzheimer's disease 36 | 658
Dull intelligence 36 | 645
Low intelligence 36 | 645
Mental Retardation 36 | 645
Mental deficiency 36 | 645
Poor school performance 36 | 645
esophageal adenocarcinoma 36 | 737
Waldenstrons macroglobulinemia 35 | 765
primary pancreatic ductal adenocarcinoma 34 | 1,109
Melanoma 33 | 711
Obesity 33 | 678
aldosterone-producing adenoma 32 | 665
non primary Sjogren syndrome sicca 32 | 891
Seizures 31 | 596
acute myeloid leukemia 31 | 783
gastric carcinoma 31 | 807
progressive supranuclear palsy 31 | 676
Cognitive delay 29 | 608
Global developmental delay 29 | 608
Mental and motor retardation 29 | 608
pancreatic carcinoma 28 | 562
Short stature 27 | 531
Muscle hypotonia 26 | 571
Neurodegenerative disease 26 | 414
medulloblastoma 26 | 720
Colorectal Neoplasms 25 | 243
Down syndrome 25 | 499
Prostatic Neoplasms 25 | 495
mucosa-associated lymphoid tissue lymphoma 25 | 484
posterior fossa group A ependymoma 25 | 468
Skin cancer 24 | 469
hepatocellular carcinoma 24 | 547
Breast Neoplasms 23 | 445
Hypertension 23 | 396
Parkinson's disease 23 | 392
gastric cancer 23 | 459
Amyotrophic lateral sclerosis 22 | 451
Depressive disorder 22 | 409
Hepatomegaly 22 | 285
Curvature of spine 21 | 282

Tissue

Digestive Tract 586 | 17,369
Skin and soft tissues 586 | 17,230
Female tissues 584 | 17,400
Endocrine System 583 | 18,159
Urinary Tract 582 | 16,678
Liver and Pancreas 581 | 16,750
Male tissues 578 | 17,142
Blood and immune system 571 | 16,909
Respiratory system 566 | 16,393
Nervous System 564 | 16,725
Cardiovascular System 545 | 15,192

Target Family

Non-IDG 311 | 12,091
Enzyme 156 | 4,145
Transcription Factor 40 | 1,400
Transporter 37 | 473
Kinase 23 | 634
GPCR 9 | 408
Epigenetic 8 | 242
Ion Channel 6 | 344
TF/Epigenetic 2 | 38
Nuclear Receptor 1 | 48

GO Component

intracellular membrane-bounded... 593 | 593
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
UDP-glucuronosyltransferase 2B15 UGT2B15 Tbio Enzyme -1.79589 61.5 83
DBIRD complex subunit ZNF326 ZNF326 Tbio Non-IDG -0.42207 3.94 120
Trafficking protein particle complex subunit 2-like protein TRAPPC2L Tdark Non-IDG -0.18066 0.74 35
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388
Filaggrin FLG Tbio Non-IDG -3.03594 1055.2 253
Eukaryotic translation initiation factor 4E transporter EIF4ENIF1 Tbio Non-IDG -1.60874 36.7 242
STE20/SPS1-related proline-alanine-rich protein kinase STK39 Tbio Kinase -2.11714 148.9 575
Sphingosine kinase 2 SPHK2 Tchem Kinase -2.21878 154.9 314
Coatomer subunit beta COPB1 Tbio Non-IDG -1.94049 82.6 148