Development Level

Tbio 43 | 10,625
Tdark 5 | 7,003
Tchem 4 | 1,890

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal spleen morphology 1 | 36
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating serum al... 1 | 79
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased rib number 1 | 59
decreased total body fat amoun... 1 | 186
decreased vertical activity 1 | 22
female infertility 1 | 34
improved glucose tolerance 1 | 56
increased blood uric acid leve... 1 | 5
increased circulating chloride... 1 | 43
increased exploration in new e... 1 | 56
increased granulocyte number 1 | 8
increased grip strength 1 | 83
increased heart rate 1 | 17
increased lean body mass 1 | 107
increased rib number 1 | 41
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
shortened RR interval 1 | 19
shortened ST segment 1 | 9

Disease

ovarian cancer 31 | 8,484
osteosarcoma 30 | 7,933
atypical teratoid / rhabdoid tumor 19 | 4,369
psoriasis 18 | 6,685
medulloblastoma, large-cell 17 | 6,234
glioblastoma 15 | 5,572
Carcinoma 14 | 2,147
lung cancer 14 | 4,466
Breast cancer 12 | 3,094
Cancer 12 | 2,346
oligodendroglioma 12 | 2,849
primitive neuroectodermal tumor 12 | 3,031
adult high grade glioma 11 | 2,148
ependymoma 11 | 2,514
colon cancer 9 | 1,475
malignant mesothelioma 9 | 3,162
pancreatic cancer 9 | 2,300
acute quadriplegic myopathy 8 | 1,157
astrocytic glioma 8 | 2,241
cystic fibrosis 8 | 1,665
esophageal adenocarcinoma 8 | 737
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
invasive ductal carcinoma 8 | 2,950
lung carcinoma 8 | 2,844
non-small cell lung cancer 8 | 2,798
pilocytic astrocytoma 8 | 3,086
spina bifida 8 | 1,064
Multiple myeloma 7 | 1,327
Pick disease 7 | 1,893
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
juvenile dermatomyositis 7 | 1,189
sonic hedgehog group medulloblastoma 7 | 1,482
subependymal giant cell astrocytoma 7 | 2,287
astrocytoma 6 | 1,493
breast carcinoma 6 | 1,614
interstitial cystitis 6 | 2,299
lung adenocarcinoma 6 | 2,713
medulloblastoma 6 | 1,524
posterior fossa group A ependymoma 6 | 1,511
Amyotrophic Lateral Sclerosis 5 | 431
Down syndrome 5 | 548
Parkinson's disease 5 | 364
Rheumatoid Arthritis 5 | 1,160
dermatomyositis 5 | 933
group 3 medulloblastoma 5 | 2,254
group 4 medulloblastoma 5 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
nasopharyngeal carcinoma 5 | 1,056
non primary Sjogren syndrome sicca 5 | 840
pediatric high grade glioma 5 | 2,712
primary pancreatic ductal adenocarcinoma 5 | 1,271
Duchenne muscular dystrophy 4 | 602
Waldenstrons macroglobulinemia 4 | 765
acute myeloid leukemia 4 | 780
atypical teratoid/rhabdoid tumor 4 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
cutaneous lupus erythematosus 4 | 1,056
pituitary cancer 4 | 1,972
ulcerative colitis 4 | 2,087
AMYOTROPHIC LATERAL SCLEROSIS 1 3 | 49
Alzheimer's disease 3 | 644
Bullous pemphigoid 3 | 17
Crohn's disease 3 | 304
Hereditary mucosal leukokeratosis 3 | 7
Nephrosis 3 | 18
active Crohn's disease 3 | 918
adrenocortical carcinoma 3 | 1,427
diabetes mellitus 3 | 1,663
fibroadenoma 3 | 557
hereditary spastic paraplegia 3 | 313
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
posterior fossa group B ependymoma 3 | 1,530
progressive supranuclear palsy 3 | 674
tuberculosis 3 | 1,557
tuberculosis and treatment for 3 months 3 | 327
Atrial Fibrillation 2 | 110
Becker muscular dystrophy 2 | 187
Brain Ischemia 2 | 87
Cerebrovascular disease 2 | 231
Cholesteatoma 2 | 13
Contact Dermatitis 2 | 80
Epidermolysis bullosa 2 | 21
Epilepsy 2 | 346
Glaucoma 2 | 134
Gout 2 | 93
Hyperhomocysteinemia 2 | 34
Kidney cancer 2 | 118
Mammary Neoplasms 2 | 410
Multiple Sclerosis 2 | 498
Neurodegenerative Disorders 2 | 37
Palmoplantar keratosis 2 | 36
active ulcerative colitis 2 | 477
ductal carcinoma in situ 2 | 1,745
glioblastoma multiforme 2 | 347
limb girdle muscular dystrophy 2A 2 | 156
limb-girdle muscular dystrophy 2 | 36
nervous system disorder 2 | 53
non-inflammatory breast cancer 2 | 208
pancreatic carcinoma 2 | 567
tuberculosis and treatment for 6 months 2 | 686

Tissue

Cardiovascular System 52 | 17,958
Digestive Tract 51 | 18,473
Endocrine System 51 | 18,512
Female tissues 51 | 18,647
Liver and Pancreas 51 | 18,136
Male tissues 51 | 17,969
Nervous System 51 | 18,561
Skin and soft tissues 51 | 18,115
Urinary Tract 51 | 18,444
Blood and immune system 50 | 17,995
Respiratory system 50 | 17,484

Target Family

Non-IDG 35 | 11,971
Enzyme 9 | 4,146
Kinase 3 | 634
Transcription Factor 3 | 1,400
Epigenetic 2 | 242

GO Component

intermediate filament cytoskel... 52 | 52
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5'-3' exoribonuclease 1 XRN1 Tbio Enzyme -2.06818 114.2 45
T-complex protein 1 subunit theta CCT8 Tbio Non-IDG -1.45966 29.4 180
Nestin NES Tbio Non-IDG -3.33502 2122.7 622
Syntaxin-binding protein 4 STXBP4 Tbio Non-IDG -0.73535 7.61 58
Keratin, type I cytoskeletal 13 KRT13 Tbio Non-IDG -2.21878 161.7 349
Nesprin-2 SYNE2 Tbio Non-IDG -2.51721 337.2 32
Probable global transcription activator SNF2L2 SMARCA2 Tchem Epigenetic -2.53909 331.1 154
Capping protein, Arp2/3 and myosin-I linker protein 2 CARMIL2 Tbio Non-IDG -0.71554 7.93 4
Nuclear factor of activated T-cells, cytoplasmic 4 NFATC4 Tbio Transcription Factor -1.90714 83.3 340
E3 ubiquitin-protein ligase Praja-2 PJA2 Tbio Enzyme -0.52612 2.59 159