Development Level

Tbio 53 | 10,625
Tdark 47 | 7,003
Tchem 1 | 1,890

Collection

Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, complete... 5 | 633
abnormal coat appearance 2 | 25
preweaning lethality, incomple... 2 | 260
abnormal behavior 1 | 226
abnormal coat- hair morphology 1 | 18
abnormal coat-hair pigmentatio... 1 | 54
abnormal embryo size 1 | 112
abnormal retina morphology 1 | 100
abnormal sleep behavior 1 | 63
abnormal vocalization 1 | 21
decreased circulating calcium ... 1 | 33
decreased circulating free fat... 1 | 39
decreased circulating insulin ... 1 | 75
decreased coping response 1 | 5
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
edema 1 | 11
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
hyperactivity 1 | 108
improved glucose tolerance 1 | 56
increased blood uric acid leve... 1 | 5
increased circulating chloride... 1 | 43
increased exploration in new e... 1 | 56
increased granulocyte number 1 | 8
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased or absent threshold ... 1 | 128
increased respiratory quotient 1 | 12
prenatal lethality 1 | 16

Disease

psoriasis 50 | 6,685
ovarian cancer 28 | 8,491
Breast cancer 20 | 3,098
Cancer 20 | 2,346
non-small cell lung cancer 20 | 2,798
osteosarcoma 20 | 7,933
lung cancer 19 | 4,473
medulloblastoma, large-cell 18 | 6,234
diabetes mellitus 16 | 1,663
malignant mesothelioma 16 | 3,163
lung adenocarcinoma 15 | 2,714
interstitial cystitis 14 | 2,299
cystic fibrosis 13 | 1,670
glioblastoma 13 | 5,572
esophageal adenocarcinoma 11 | 737
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
pancreatic cancer 11 | 2,300
spina bifida 11 | 1,064
Atopic dermatitis 10 | 944
Palmoplantar keratosis 10 | 36
atypical teratoid / rhabdoid tumor 10 | 4,369
breast carcinoma 10 | 1,614
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,956
lung carcinoma 10 | 2,844
nasopharyngeal carcinoma 10 | 1,056
subependymal giant cell astrocytoma 10 | 2,287
adult high grade glioma 9 | 2,148
colon cancer 9 | 1,475
invasive ductal carcinoma 9 | 2,950
primitive neuroectodermal tumor 9 | 3,031
sonic hedgehog group medulloblastoma 9 | 1,482
Carcinoma 8 | 2,147
ductal carcinoma in situ 8 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
oligodendroglioma 8 | 2,849
pituitary cancer 8 | 1,972
posterior fossa group B ependymoma 8 | 1,530
atypical teratoid/rhabdoid tumor 7 | 1,095
pilocytic astrocytoma 7 | 3,086
ulcerative colitis 7 | 2,087
Keratosis 6 | 34
ependymoma 6 | 2,514
gastric carcinoma 6 | 832
pediatric high grade glioma 6 | 2,712
posterior fossa group A ependymoma 6 | 1,511
primary pancreatic ductal adenocarcinoma 6 | 1,271
Adenoma 5 | 165
Alopecia 5 | 55
Amyotrophic Lateral Sclerosis 5 | 432
Cardiomyopathy 5 | 110
Epidermolysis bullosa simplex 5 | 9
Epidermolytic hyperkeratosis 5 | 13
Neoplastic Cell Transformation 5 | 81
Pachyonychia Congenita 5 | 9
Pick disease 5 | 1,893
astrocytic glioma 5 | 2,241
cutaneous lupus erythematosus 5 | 1,056
group 4 medulloblastoma 5 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
Arrhythmogenic right ventricular cardiomyopathy 4 | 27
Basal cell carcinoma 4 | 31
Cataract 4 | 104
Cerebrovascular disease 4 | 231
Congenital ichthyosiform erythroderma 4 | 27
Contact Dermatitis 4 | 80
Dilated cardiomyopathy 4 | 51
Duchenne muscular dystrophy 4 | 602
Epidermolysis bullosa 4 | 21
Epilepsy 4 | 346
Liver disease 4 | 219
Multiple myeloma 4 | 1,327
Myopathy 4 | 128
Polycystic Ovary Syndrome 4 | 334
Syringoma 4 | 10
acute quadriplegic myopathy 4 | 1,157
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
juvenile dermatomyositis 4 | 1,189
periodontitis 4 | 269
AMYOTROPHIC LATERAL SCLEROSIS 1 3 | 49
Arrhythmogenic Right Ventricular Dysplasia 3 | 10
Barrett's esophagus 3 | 185
Becker muscular dystrophy 3 | 187
Corneal dystrophy 3 | 15
Down syndrome 3 | 548
Mammary Neoplasms 3 | 410
Monilethrix 3 | 17
Neoplasm Invasiveness 3 | 127
Papilloma 3 | 27
Parkinson's disease 3 | 364
Pleomorphic adenoma 3 | 18
Prostatic Neoplasms 3 | 471
Renal Cell Carcinoma 3 | 199
Skin disease 3 | 65
Squamous cell carcinoma of esophagus 3 | 82
Stomach Neoplasms 3 | 282
acute myeloid leukemia 3 | 785
aldosterone-producing adenoma 3 | 664
astrocytoma 3 | 1,493
group 3 medulloblastoma 3 | 2,254
progressive supranuclear palsy 3 | 674

Tissue

Female tissues 90 | 18,646
Nervous System 84 | 18,560
Digestive Tract 83 | 18,472
Endocrine System 83 | 18,511
Skin and soft tissues 83 | 18,114
Urinary Tract 79 | 18,443
Cardiovascular System 77 | 17,957
Liver and Pancreas 75 | 18,135
Male tissues 73 | 17,968
Blood and immune system 70 | 17,994
Respiratory system 69 | 17,483

Target Family

Non-IDG 96 | 11,969
Kinase 3 | 634
Enzyme 1 | 4,146
Transporter 1 | 473

GO Component

intermediate filament 101 | 101
nucleus 5,106 | 5,106
cytoplasm 4,984 | 4,984
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,264 | 3,264
extracellular exosome 2,757 | 2,757
nucleoplasm 2,716 | 2,716
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 536 | 536
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glial fibrillary acidic protein GFAP Tbio Non-IDG -3.47927 2665.9 1710
Keratin, type II cytoskeletal 80 KRT80 Tbio Non-IDG -0.75979 5.56 91
Nucleoside diphosphate kinase A NME1 Tbio Kinase -2.97569 843.2 611
Plakophilin-1 PKP1 Tbio Non-IDG -1.85135 73.8 91
NCK-interacting protein with SH3 domain NCKIPSD Tbio Non-IDG -0.98081 14.9 92
Gap junction alpha-1 protein GJA1 Tbio Non-IDG -3.56943 3888.4 772
Filaggrin FLG Tbio Non-IDG -3.00653 979.5 163
Keratin, type I cytoskeletal 23 KRT23 Tbio Non-IDG -1.53247 33.2 144
Keratin, type I cytoskeletal 9 KRT9 Tbio Non-IDG -2.32570 211.9 113
Keratin-associated protein 13-2 KRTAP13-2 Tdark Non-IDG 0.00000 0