Development Level

Tbio 53 | 11,445
Tdark 45 | 6,588
Tchem 1 | 1,598
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
decreased circulating HDL chol... 2 | 68
decreased circulating insulin ... 2 | 76
embryonic lethality prior to t... 2 | 278
abnormal coat appearance 1 | 31
abnormal coat- hair morphology 1 | 19
abnormal coat-hair pigmentatio... 1 | 64
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal vocalization 1 | 21
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating sodium l... 1 | 22
decreased coping response 1 | 8
decreased fasted circulating g... 1 | 65
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
enlarged uterus 1 | 11
hyperactivity 1 | 148
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased blood uric acid leve... 1 | 5
increased body length 1 | 32
increased circulating chloride... 1 | 41
increased granulocyte number 1 | 1
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74

Disease

Carcinoma 59 | 11,493
psoriasis 49 | 6,694
ovarian cancer 27 | 8,520
Breast cancer 21 | 3,578
non-small cell lung cancer 20 | 2,890
Cancer 19 | 2,499
lung cancer 19 | 4,740
osteosarcoma 19 | 7,950
medulloblastoma, large-cell 17 | 6,241
malignant mesothelioma 16 | 3,232
atypical teratoid / rhabdoid tumor 14 | 5,112
diabetes mellitus 14 | 1,728
glioblastoma 14 | 5,792
interstitial cystitis 14 | 2,312
lung adenocarcinoma 14 | 2,716
cystic fibrosis 13 | 1,696
Palmoplantar keratosis 12 | 74
adult high grade glioma 12 | 3,801
ependymoma 12 | 4,679
esophageal adenocarcinoma 11 | 737
pancreatic cancer 11 | 2,398
spina bifida 11 | 1,074
Atopic dermatitis 10 | 952
group 3 medulloblastoma 10 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
subependymal giant cell astrocytoma 10 | 2,287
Autosomal recessive predisposition 9 | 1,442
Kidney cancer 9 | 2,613
breast carcinoma 9 | 1,638
colon cancer 9 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
lung carcinoma 9 | 2,843
nasopharyngeal carcinoma 9 | 1,058
ductal carcinoma in situ 8 | 1,745
invasive ductal carcinoma 8 | 2,951
oligodendroglioma 8 | 2,850
primitive neuroectodermal tumor 8 | 3,035
Alopecia 7 | 115
Astrocytoma, Pilocytic 7 | 3,081
Hyperhidrosis disorder 7 | 81
Increased sweating 7 | 81
Mammary Neoplasms 7 | 425
Sweating 7 | 81
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
pituitary cancer 7 | 1,972
Breast Neoplasms 6 | 445
Dystrophia unguium 6 | 53
Keratosis 6 | 37
Liver Cirrhosis, Experimental 6 | 769
Pachyonychia congenita 6 | 10
astrocytic glioma 6 | 2,597
ulcerative colitis 6 | 1,819
Abnormal blistering of the skin 5 | 54
Amyotrophic lateral sclerosis 5 | 451
Arrhythmogenic right ventricular cardiomyopathy 5 | 30
Basal cell carcinoma 5 | 54
Blister of skin 5 | 54
Cardiomyopathy 5 | 116
Cell Transformation, Neoplastic 5 | 97
Dilated cardiomyopathy 5 | 56
Epidermolysis bullosa simplex 5 | 9
Epidermolytic hyperkeratosis 5 | 14
Erythema 5 | 58
Flushing 5 | 60
Leukokeratosis 5 | 19
Leukoplakia, Oral 5 | 20
Nail Diseases 5 | 24
Nail abnormality 5 | 22
Nail dysplasia 5 | 52
Neoplastic Cell Transformation 5 | 89
Pick disease 5 | 1,894
Skin bulla 5 | 54
cutaneous lupus erythematosus 5 | 1,057
gastric carcinoma 5 | 807
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
posterior fossa group B ependymoma 5 | 416
primary pancreatic ductal adenocarcinoma 5 | 1,109
Adenoma 4 | 167
Cardiomyopathy, Dilated 4 | 83
Contact Dermatitis 4 | 81
Dermatitis, Contact 4 | 71
Epidermolysis bullosa 4 | 21
Epilepsy 4 | 792
Failure to gain weight 4 | 365
Growth delay 4 | 114
Growth failure 4 | 114
Growth retardation 4 | 115
Liver cancer 4 | 604
Liver disease 4 | 237
Multiple myeloma 4 | 1,332
Myopathy 4 | 185
Neoplasm Invasiveness 4 | 161
Onychogryposis 4 | 13
Parkinson's disease 4 | 392
Pediatric failure to thrive 4 | 365
Polycystic ovary syndrome 4 | 360
Poor growth 4 | 114
Very poor growth 4 | 114
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
periodontitis 4 | 293

Tissue

Endocrine System 71 | 18,159
Skin and soft tissues 70 | 17,230
Female tissues 67 | 17,400
Digestive Tract 64 | 17,369
Blood and immune system 59 | 16,909
Male tissues 52 | 17,142
Liver and Pancreas 49 | 16,750
Nervous System 48 | 16,725
Respiratory system 46 | 16,393
Urinary Tract 46 | 16,678
Cardiovascular System 40 | 15,192

Target Family

Non-IDG 94 | 12,091
Kinase 3 | 634
Enzyme 1 | 4,145
GPCR 1 | 408
Transporter 1 | 473

GO Component

intermediate filament 100 | 100
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Keratin-associated protein 17-1 KRTAP17-1 Tdark Non-IDG 0.00000 0
Desmin DES Tbio Non-IDG -1.56068 36.6 991
CAP-Gly domain-containing linker protein 1 CLIP1 Tbio Non-IDG -2.54943 343.7 221
Keratin, type II cytoskeletal 8 KRT8 Tbio Non-IDG -2.87670 710.7 1827
Keratin, type II cytoskeletal 2 oral KRT76 Tdark Non-IDG -0.28255 1.97 156
Lamin tail domain-containing protein 1 LMNTD1 Tdark Non-IDG 0.00000 1.11 76
Plakophilin-2 PKP2 Tbio Non-IDG -2.10355 135.3 243
Keratin, type I cytoskeletal 18 KRT18 Tbio Non-IDG -3.05211 1057.8 1953
Plakophilin-1 PKP1 Tbio Non-IDG -1.86062 76.3 103
Keratin, type II cytoskeletal 80 KRT80 Tbio Non-IDG -0.75979 5.56 110