Development Level

Tbio 35 | 11,178
Tchem 6 | 1,885
Tdark 3 | 6,569

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased circulating HDL chol... 2 | 80
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal skin morphology 1 | 50
absent startle reflex 1 | 24
cataract 1 | 92
decreased circulating chloride... 1 | 30
decreased circulating triglyce... 1 | 79
decreased cornea thickness 1 | 2
decreased lymphocyte cell numb... 1 | 83
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
enlarged heart 1 | 210
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
prolonged QRS complex duration 1 | 8
short tibia 1 | 97
small kidney 1 | 16
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 30 | 11,192
ovarian cancer 22 | 8,297
osteosarcoma 20 | 7,766
glioblastoma 19 | 5,635
psoriasis 16 | 6,514
malignant mesothelioma 15 | 3,135
group 3 medulloblastoma 14 | 4,002
atypical teratoid / rhabdoid tumor 13 | 4,971
lung cancer 13 | 4,607
medulloblastoma, large-cell 13 | 6,086
adult high grade glioma 11 | 3,701
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,204
Breast cancer 10 | 3,469
primitive neuroectodermal tumor 10 | 2,957
ependymoma 9 | 4,559
invasive ductal carcinoma 9 | 2,867
Cancer 8 | 2,388
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,902
non-small cell lung cancer 8 | 2,799
Autosomal recessive predisposition 7 | 1,407
astrocytic glioma 7 | 2,530
ductal carcinoma in situ 7 | 1,686
Kidney cancer 6 | 2,548
breast carcinoma 6 | 1,589
lung adenocarcinoma 6 | 2,627
oligodendroglioma 6 | 2,768
Atopic dermatitis 5 | 915
adrenocortical carcinoma 5 | 1,385
colon cancer 5 | 1,428
group 4 medulloblastoma 5 | 1,806
non primary Sjogren syndrome sicca 5 | 861
pancreatic cancer 5 | 2,322
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,911
Astrocytoma, Pilocytic 4 | 3,006
Dull intelligence 4 | 634
Endometriosis 4 | 521
Epilepsy 4 | 775
Intellectual disability 4 | 998
Low intelligence 4 | 634
Mental Retardation 4 | 634
Mental deficiency 4 | 634
Poor school performance 4 | 634
Seizures 4 | 584
interstitial cystitis 4 | 2,237
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,872
pediatric high grade glioma 4 | 1,035
pituitary cancer 4 | 1,915
Anemia 3 | 353
Cerebellar Ataxia 3 | 302
Depressive disorder 3 | 401
Failure to gain weight 3 | 359
Fatigue 3 | 176
Hypogonadism 3 | 169
Muscle hypotonia 3 | 562
Pediatric failure to thrive 3 | 359
Pick disease 3 | 1,856
Polycystic ovary syndrome 3 | 348
Retinitis Pigmentosa 3 | 223
active Crohn's disease 3 | 882
cutaneous lupus erythematosus 3 | 1,016
lung carcinoma 3 | 2,755
nasopharyngeal carcinoma 3 | 1,024
sonic hedgehog group medulloblastoma 3 | 459
spina bifida 3 | 1,053
subependymal giant cell astrocytoma 3 | 2,230
Amyotrophic lateral sclerosis 2 | 437
Bipolar Disorder 2 | 646
Cognitive delay 2 | 596
Concave bridge of nose 2 | 191
Depressed nasal bridge 2 | 191
Depressed nasal root/bridge 2 | 191
Global developmental delay 2 | 596
Hemoglobin low 2 | 123
Highly variable severity 2 | 149
Liver cancer 2 | 589
Mental and motor retardation 2 | 596
Progressive disorder 2 | 139
Proteinuria 2 | 143
Short stature 2 | 514
Small head 2 | 366
Strabismus 2 | 265
Thin skin 2 | 44
Variable expressivity 2 | 149
Waldenstrons macroglobulinemia 2 | 742
active ulcerative colitis 2 | 736
acute myeloid leukemia 2 | 760
aldosterone-producing adenoma 2 | 646
dermatomyositis 2 | 941
diabetes mellitus 2 | 1,683
esophageal adenocarcinoma 2 | 696
fibroadenoma 2 | 538
hepatocellular carcinoma 2 | 536
juvenile dermatomyositis 2 | 1,147
medulloblastoma 2 | 702
posterior fossa group A ependymoma 2 | 456
primary Sjogren syndrome 2 | 710
progressive supranuclear palsy 2 | 656
tuberculosis 2 | 1,963
tuberculosis and treatment for 6 months 2 | 399
ulcerative colitis 2 | 1,765

Tissue

Endocrine System 44 | 18,159
Male tissues 43 | 17,142
Female tissues 42 | 17,400
Nervous System 42 | 16,725
Skin and soft tissues 42 | 17,230
Blood and immune system 41 | 16,909
Digestive Tract 41 | 17,369
Liver and Pancreas 41 | 16,750
Respiratory system 41 | 16,393
Urinary Tract 41 | 16,678
Cardiovascular System 40 | 15,192

Target Family

Non-IDG 26 | 12,091
Enzyme 7 | 4,145
Kinase 6 | 634
Transcription Factor 4 | 1,400
Nuclear Receptor 1 | 48

GO Component

intercellular bridge 44 | 44
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-35 RAB35 Tbio Enzyme -1.61645 42.9 224
Homeobox protein PKNOX2 PKNOX2 Tbio Transcription Factor -1.23291 18.2 161
Chromosome-associated kinesin KIF4A KIF4A Tchem Non-IDG -1.91717 78.0 157
KRR1 small subunit processome component homolog KRR1 Tbio Non-IDG -0.93152 9.98 134
Protein FAM50B FAM50B Tdark Non-IDG -0.70635 5.37 49
Steroid receptor RNA activator 1 SRA1 Tbio Non-IDG -2.78991 595.4 160
Fanconi-associated nuclease 1 FAN1 Tbio Enzyme -2.06970 115.9 85
Centrosomal protein of 131 kDa CEP131 Tbio Non-IDG -1.78486 61.9 82
RelA-associated inhibitor PPP1R13L Tbio Non-IDG -1.76131 64.5 185
Hematopoietic progenitor cell antigen CD34 CD34 Tbio Non-IDG -4.14691 13698.4 1952