Development Level

Tbio 784 | 11,651
Tchem 247 | 1,388
Tclin 221 | 612
Tdark 166 | 6,593

Collection

RFA-RM-18-021 80 | 328
GPCR: IDG Consortium (Targets) 48 | 126
Ion Channel: IDG Consortium (T... 31 | 99
GPCR: IDG Consortium (Complete... 16 | 25
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 47 | 979
preweaning lethality, incomple... 44 | 499
decreased vertical activity 26 | 208
abnormal behavior 24 | 298
enlarged heart 22 | 210
embryonic lethality prior to t... 16 | 278
abnormal bone structure 14 | 187
abnormal embryo size 14 | 220
abnormal heart morphology 14 | 162
decreased total body fat amoun... 14 | 207
hyperactivity 13 | 148
abnormal seminal vesicle morph... 12 | 114
decreased body weight 12 | 161
small superior vagus ganglion 12 | 74
decreased grip strength 11 | 116
embryonic lethality prior to o... 11 | 239
increased lean body mass 11 | 172
abnormal gait 10 | 69
decreased prepulse inhibition 10 | 82
impaired glucose tolerance 10 | 75
increased startle reflex 10 | 112
increased total body fat amoun... 10 | 134
abnormal eye morphology 9 | 68
abnormal kidney morphology 9 | 65
decreased circulating insulin ... 9 | 76
decreased lymphocyte cell numb... 9 | 83
increased circulating alkaline... 9 | 122
abnormal epididymis morphology 8 | 42
decreased bone mineral content 8 | 151
decreased fasted circulating g... 8 | 65
decreased mean corpuscular vol... 8 | 79
enlarged spleen 8 | 41
hypoactivity 8 | 132
improved glucose tolerance 8 | 79
increased mean corpuscular vol... 8 | 92
prolonged QT interval 8 | 38
abnormal skin morphology 7 | 50
cardiovascular system phenotyp... 7 | 36
decreased bone mineral density 7 | 126
decreased lean body mass 7 | 135
enlarged epididymis 7 | 31
increased circulating choleste... 7 | 66
increased circulating sodium l... 7 | 71
increased leukocyte cell numbe... 7 | 47
increased mean corpuscular hem... 7 | 96
limb grasping 7 | 41
prolonged ST segment 7 | 36
tremors 7 | 39
abnormal sleep behavior 6 | 70
decreased circulating alkaline... 6 | 46
increased circulating HDL chol... 6 | 80
increased monocyte cell number 6 | 63
pale yolk sac 6 | 25
pallor 6 | 34
abnormal retina morphology 5 | 71
cataract 5 | 92
decreased body length 5 | 101
decreased circulating HDL chol... 5 | 68
decreased circulating choleste... 5 | 93
decreased circulating creatini... 5 | 39
decreased circulating triglyce... 5 | 79
decreased eosinophil cell numb... 5 | 24
decreased mean corpuscular hem... 5 | 50
decreased startle reflex 5 | 75
embryonic growth retardation 5 | 106
hydrometra 5 | 53
increased circulating chloride... 5 | 41
increased circulating creatini... 5 | 38
increased circulating iron lev... 5 | 30
increased fasted circulating g... 5 | 76
increased grip strength 5 | 41
increased heart weight 5 | 62
increased lymphocyte cell numb... 5 | 32
increased mean platelet volume 5 | 45
increased neutrophil cell numb... 5 | 46
male infertility 5 | 123
short tibia 5 | 97
small testis 5 | 58
abnormal lens morphology 4 | 81
abnormal limb bud morphology 4 | 17
abnormal neural tube closure 4 | 46
abnormal pancreas morphology 4 | 13
abnormal spleen morphology 4 | 55
abnormal testis morphology 4 | 43
abnormal vibrissa morphology 4 | 25
absent vibrissae 4 | 12
anophthalmia 4 | 33
decreased blood urea nitrogen ... 4 | 51
decreased circulating glucose ... 4 | 126
decreased mean corpuscular hem... 4 | 31
edema 4 | 59
increased bone mineral content 4 | 108
increased circulating calcium ... 4 | 34
increased circulating triglyce... 4 | 42
increased eosinophil cell numb... 4 | 11
increased erythrocyte cell num... 4 | 39
increased hematocrit 4 | 46
increased or absent threshold ... 4 | 101
polycystic kidney 4 | 15
thrombocytopenia 4 | 56

Disease

Carcinoma 1,048 | 11,493
psoriasis 618 | 6,694
osteosarcoma 600 | 7,950
ovarian cancer 580 | 8,520
medulloblastoma, large-cell 495 | 6,241
glioblastoma 490 | 5,792
lung cancer 461 | 4,740
atypical teratoid / rhabdoid tumor 415 | 5,112
ependymoma 398 | 4,679
lung carcinoma 379 | 2,843
adult high grade glioma 340 | 3,801
Cancer 331 | 2,499
Astrocytoma, Pilocytic 326 | 3,081
Kidney cancer 322 | 2,613
non-small cell lung cancer 319 | 2,890
malignant mesothelioma 307 | 3,232
Breast cancer 299 | 3,578
interstitial cystitis 299 | 2,312
group 3 medulloblastoma 298 | 4,104
lung adenocarcinoma 295 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 293 | 3,291
invasive ductal carcinoma 293 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 291 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 282 | 2,955
pancreatic cancer 269 | 2,398
oligodendroglioma 262 | 2,850
primitive neuroectodermal tumor 233 | 3,035
astrocytic glioma 228 | 2,597
tuberculosis 219 | 2,010
ulcerative colitis 217 | 1,819
pituitary cancer 214 | 1,972
Schizophrenia 210 | 1,160
subependymal giant cell astrocytoma 209 | 2,287
cystic fibrosis 188 | 1,696
Autosomal recessive predisposition 182 | 1,442
ductal carcinoma in situ 182 | 1,745
cutaneous lupus erythematosus 181 | 1,057
colon cancer 168 | 1,478
diabetes mellitus 167 | 1,728
breast carcinoma 154 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 153 | 1,962
group 4 medulloblastoma 144 | 1,855
Pick disease 132 | 1,894
Rheumatoid arthritis 123 | 1,191
adrenocortical carcinoma 123 | 1,428
Bipolar Disorder 117 | 666
Epilepsy 113 | 792
Melanoma 110 | 711
primary pancreatic ductal adenocarcinoma 105 | 1,109
active Crohn's disease 100 | 922
Liver Cirrhosis, Experimental 96 | 769
Multiple Sclerosis 96 | 540
pediatric high grade glioma 96 | 1,064
Obesity 93 | 678
Hypertension 91 | 396
nasopharyngeal carcinoma 91 | 1,058
Depressive disorder 89 | 409
Skin cancer 86 | 469
primary Sjogren syndrome 86 | 735
astrocytoma 85 | 1,146
Intellectual disability 84 | 1,016
gastric carcinoma 83 | 807
mucosa-associated lymphoid tissue lymphoma 83 | 484
Liver cancer 81 | 604
active ulcerative colitis 81 | 764
esophageal adenocarcinoma 80 | 737
Alzheimer's disease 79 | 658
Kidney disease 79 | 430
juvenile dermatomyositis 76 | 1,187
Alcoholic Intoxication, Chronic 75 | 289
Asthma 75 | 385
Atopic dermatitis 74 | 952
Mental Depression 74 | 333
dermatomyositis 74 | 966
spina bifida 72 | 1,074
Down syndrome 71 | 499
Seizures 71 | 596
Duchenne muscular dystrophy 68 | 601
aldosterone-producing adenoma 67 | 665
non primary Sjogren syndrome sicca 65 | 891
nephrosclerosis 64 | 333
Autistic Disorder 63 | 364
acute quadriplegic myopathy 63 | 1,158
Dull intelligence 62 | 645
Low intelligence 62 | 645
Mental Retardation 62 | 645
Mental deficiency 62 | 645
Poor school performance 62 | 645
Major Depressive Disorder 60 | 301
Anemia 59 | 365
pancreatic carcinoma 58 | 562
Endometriosis 57 | 540
Mood Disorders 56 | 184
medulloblastoma 56 | 720
Multiple myeloma 55 | 1,332
Muscle hypotonia 55 | 571
Parkinson's disease 55 | 392
Prostatic Neoplasms 55 | 495
Hypersensitivity reaction type II disease 54 | 253
Hypertensive disease 51 | 292

Tissue

Endocrine System 1,329 | 18,159
Digestive Tract 1,288 | 17,369
Female tissues 1,278 | 17,400
Skin and soft tissues 1,264 | 17,230
Nervous System 1,257 | 16,725
Male tissues 1,252 | 17,142
Liver and Pancreas 1,233 | 16,750
Urinary Tract 1,233 | 16,678
Blood and immune system 1,231 | 16,909
Respiratory system 1,175 | 16,393
Cardiovascular System 1,055 | 15,192

Target Family

Non-IDG 581 | 12,091
GPCR 261 | 408
Transporter 226 | 473
Ion Channel 157 | 344
Enzyme 118 | 4,145
Kinase 64 | 634
oGPCR 11 | 421

GO Component

integral component of plasma m... 1,418 | 1,418
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5
Tetraspanin-16 TSPAN16 Tdark Non-IDG -1.99505 87.0 42
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388
UPF0577 protein KIAA1324 KIAA1324 Tbio Non-IDG -1.30268 19.8 137
Leukotriene B4 receptor 1 LTB4R Tchem GPCR -2.74171 557.6 365
Long-wave-sensitive opsin 1 OPN1LW Tbio GPCR -2.37983 238.7 47
Medium-wave-sensitive opsin 1 OPN1MW Tbio GPCR -0.97721 8.41 18
Mas-related G-protein coupled receptor member X1 MRGPRX1 Tchem GPCR -1.21830 18.4 75
Macrophage receptor MARCO MARCO Tbio Non-IDG -2.37206 210.3 189
Tumor necrosis factor receptor superfamily member 4 TNFRSF4 Tbio Non-IDG -2.60147 430.2 524