Development Level

Tbio 16 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased total body fat amoun... 2 | 207
preweaning lethality, complete... 2 | 979
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal lens morphology 1 | 81
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased coping response 1 | 8
decreased heart rate variabili... 1 | 13
decreased vertical activity 1 | 208
enlarged spleen 1 | 41
increased bone mineral density 1 | 72
increased circulating bilirubi... 1 | 16
increased circulating fructosa... 1 | 13
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
male infertility 1 | 123
shortened RR interval 1 | 17

Disease

Zellweger syndrome 11 | 37
Epilepsy 10 | 792
Peroxisomal disease 10 | 22
Addison Disease 9 | 18
Adrenal cortical hypofunction 9 | 23
Cataract 9 | 297
Infantile Refsum disease 9 | 23
Optic Atrophy 9 | 242
Seizures 9 | 596
Abnormal behavior 8 | 52
Abnormal skeletal development 8 | 60
Abnormality of metabolism/homeostasis 8 | 134
Abnormality of retinal pigmentation 8 | 111
Abnormality of the liver 8 | 21
Abnormality of the palate 8 | 17
Adrenoleukodystrophy, Neonatal 8 | 13
Anteverted nostril 8 | 191
Bilateral single transverse palmar creases 8 | 34
Blepharoptosis 8 | 231
Broad flat nasal bridge 8 | 236
Byzanthine arch palate 8 | 194
Clouding of corneal stroma 8 | 50
Concave bridge of nose 8 | 195
Congenital Epicanthus 8 | 177
Corneal Opacity 8 | 53
Death in early childhood 8 | 82
Death in infancy 8 | 82
Decreased to absent deep tendon reflexes 8 | 42
Depressed nasal bridge 8 | 195
Depressed nasal root/bridge 8 | 195
Developmental regression 8 | 95
Difficulties with night vision 8 | 87
Electroencephalogram abnormal 8 | 101
Elevated levels of phytanic acid 8 | 15
Embryotoxon 8 | 28
Failure to gain weight 8 | 365
Flat back of the head 8 | 26
Flat face 8 | 52
Flat occiput 8 | 26
Global developmental delay, severe 8 | 47
Hepatomegaly 8 | 285
High forehead 8 | 102
Hydronephrosis 8 | 89
Hyperreflexia 8 | 209
Hypertrophy of clitoris 8 | 40
Hypotonia, severe 8 | 33
Icterus 8 | 82
Impaired cognition 8 | 96
Increased head circumference 8 | 147
Increased size of skull 8 | 147
Infantile Refsum Disease (disorder) 8 | 13
Liver Failure 8 | 73
Liver diseases 8 | 87
Long narrow head 8 | 75
Loss of developmental milestones 8 | 95
Low Vision 8 | 174
Malabsorption 8 | 82
Malformations of Cortical Development, Group II 8 | 31
Malformed pinnae 8 | 37
Mental deterioration in childhood 8 | 95
Mental impairment 8 | 95
Movement Disorders 8 | 55
Muscle Spasticity 8 | 195
Muscle weakness, progressive 8 | 22
Narrow cranium shape 8 | 75
Narrow head shape 8 | 75
Narrow skull shape 8 | 75
Nasal bridge wide 8 | 236
Neurodevelopmental regression 8 | 95
Night Blindness 8 | 101
Osteochondrodysplasias 8 | 72
Pediatric failure to thrive 8 | 365
Penile hypospadias 8 | 106
Polymicrogyria 8 | 48
Posterior embryotoxon 8 | 28
Premature Birth 8 | 77
Premature birth of newborn 8 | 67
Profound global developmental delay 8 | 17
Psychomotor regression 8 | 95
Psychomotor regression beginning in infancy 8 | 95
Psychomotor regression in infants 8 | 95
Psychomotor regression, progressive 8 | 95
Psychomotor retardation, profound 8 | 17
Pyloric Stenosis 8 | 47
Respiratory Insufficiency 8 | 132
Respiratory function loss 8 | 121
Retinal pigment epithelial abnormality 8 | 111
Sensorineural Hearing Loss (disorder) 8 | 284
Severe psychomotor retardation 8 | 47
Stippled epiphyses 8 | 28
Strabismus 8 | 270
Tall forehead 8 | 102
Turridolichocephaly 8 | 75
Underdeveloped brows 8 | 38
Underdeveloped supraorbital ridges 8 | 38
Upward slant of palpebral fissure 8 | 75
Very long chain fatty acid accumulation 8 | 13
Visual Impairment 8 | 174
Visual field constriction 8 | 36
Wide anterior fontanel 8 | 44

Tissue

Blood and immune system 17 | 16,909
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678
Cardiovascular System 16 | 15,192

Target Family

Non-IDG 12 | 12,091
Transporter 3 | 473
Enzyme 2 | 4,145

GO Component

integral component of peroxiso... 17 | 17
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Peroxisomal membrane protein PEX16 PEX16 Tbio Non-IDG -1.43594 27.8 78
Fatty acyl-CoA reductase 1 FAR1 Tbio Enzyme -1.65427 43.8 27
Peroxisome biogenesis factor 2 PEX2 Tbio Non-IDG -1.76849 57.3 170
Peroxisomal membrane protein PMP34 SLC25A17 Tbio Transporter -2.14978 108.6 79
Peroxisomal biogenesis factor 3 PEX3 Tbio Non-IDG -1.79362 72.7 79
Peroxisomal membrane protein 11C PEX11G Tbio Non-IDG -0.26324 0.99 45
Peroxisome assembly protein 26 PEX26 Tbio Non-IDG -1.04829 11.8 85
Peroxisomal membrane protein 11B PEX11B Tbio Non-IDG -1.00971 10.5 80
Very long-chain acyl-CoA synthetase SLC27A2 Tbio Transporter -1.73251 54.7 121
Peroxisomal membrane protein 2 PXMP2 Tdark Non-IDG -0.43669 3.82 115