Development Level

Tbio 19 | 11,445
Tdark 5 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to t... 2 | 278
increased total body fat amoun... 2 | 134
abnormal bone structure 1 | 187
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
absent vibrissae 1 | 12
decreased bone mineral content 1 | 151
decreased cardiac stroke volum... 1 | 6
decreased circulating creatine... 1 | 4
decreased food intake 1 | 13
decreased heart weight 1 | 27
embryonic lethality prior to o... 1 | 239
impaired righting response 1 | 26
increased fasted circulating g... 1 | 76
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87

Disease

ovarian cancer 14 | 8,520
osteosarcoma 11 | 7,950
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung cancer 8 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
pancreatic cancer 7 | 2,398
psoriasis 7 | 6,694
Carcinoma 6 | 11,493
ependymoma 6 | 4,679
malignant mesothelioma 6 | 3,232
medulloblastoma, large-cell 6 | 6,241
Pick disease 5 | 1,894
astrocytic glioma 5 | 2,597
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
Breast cancer 4 | 3,578
Multiple myeloma 4 | 1,332
adult high grade glioma 4 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
invasive ductal carcinoma 4 | 2,951
oligodendroglioma 4 | 2,850
Acidosis, Lactic 3 | 97
Autosomal recessive predisposition 3 | 1,442
Cerebellar Ataxia 3 | 304
Dystonia 3 | 164
Lactic acidemia 3 | 95
Leigh disease 3 | 100
Neuropathy 3 | 261
Obesity 3 | 678
acute myeloid leukemia 3 | 783
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
non-small cell lung cancer 3 | 2,890
pancreatic carcinoma 3 | 562
Abnormal vision 2 | 52
Astrocytoma, Pilocytic 2 | 3,081
Babesiosis 2 | 14
Cardiomyopathy 2 | 116
Cataract 2 | 297
Chagas disease 2 | 39
Congenital Bilateral Cataracts 2 | 50
Congenital cataract 2 | 50
Cytochrome-c Oxidase Deficiency 2 | 17
Deafness dystonia syndrome 2 | 21
Encephalopathies 2 | 43
Epilepsy 2 | 792
Hepatomegaly 2 | 285
Highly variable severity 2 | 157
Hypertrophic Cardiomyopathy 2 | 117
Hypoglycemia 2 | 152
Intellectual disability 2 | 1,016
Lactic acidosis 2 | 51
Multiple acyl-CoA dehydrogenase deficiency 2 | 25
Muscle hypotonia 2 | 571
Myopathy 2 | 185
Peripheral Neuropathy 2 | 134
Ragged-red fibers 2 | 21
Variable expressivity 2 | 157
Vomiting 2 | 116
adrenocortical carcinoma 2 | 1,428
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
cytochrome-c oxidase deficiency disease 2 | 19
ductal carcinoma in situ 2 | 1,745
hereditary spastic paraplegia 2 | 318
inflammatory breast cancer 2 | 286
lung carcinoma 2 | 2,843
non primary Sjogren syndrome sicca 2 | 891
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
primitive neuroectodermal tumor 2 | 3,035
progressive supranuclear palsy 2 | 676
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Amelogenesis imperfecta type 4 1 | 8
Beriberi 1 | 12
Blindness, Cortical 1 | 24
CREST Syndrome 1 | 16
Coenzyme Q10 deficiency disease 1 | 8
Cortical visual impairment 1 | 24
Decreased visual acuity, slowly progressive 1 | 13
Episodic vomiting 1 | 10
Frequent vomiting 1 | 10
Glycosuria 1 | 29
Leber hereditary optic neuropathy 1 | 14
Macrocephaly 1 | 11
Methemoglobinemia 1 | 17
Mitochondrial Complex III Deficiency 1 | 9
Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes 1 | 9
Mitochondrial respiratory chain defects 1 | 15
Optic Neuropathy 1 | 12
Oral candidiasis 1 | 10
Photosensitivity of skin 1 | 51
Reye syndrome 1 | 11
Sensorineural hearing loss, bilateral 1 | 18
Slow decrease in visual acuity 1 | 13
alcohol-related neurodevelopmental disorder 1 | 13
genital abnormal 1 | 17
reproductive system abnormality 1 | 17

Tissue

Blood and immune system 25 | 16,909
Endocrine System 25 | 18,159
Male tissues 25 | 17,142
Respiratory system 25 | 16,393
Cardiovascular System 24 | 15,192
Digestive Tract 24 | 17,369
Female tissues 24 | 17,400
Liver and Pancreas 24 | 16,750
Nervous System 24 | 16,725
Skin and soft tissues 24 | 17,230
Urinary Tract 24 | 16,678

Target Family

Enzyme 12 | 4,145
Non-IDG 11 | 12,091
Ion Channel 1 | 344
Transporter 1 | 473

GO Component

integral component of mitochon... 25 | 25
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MICOS complex subunit MIC26 APOO Tbio Non-IDG -1.25338 18.9 141
Mitochondrial thiamine pyrophosphate carrier SLC25A19 Tbio Transporter -2.34612 194.5 69
Cytochrome b MT-CYB Tbio Non-IDG -3.77047 5856.5 134
Calcium uniporter protein, mitochondrial MCU Tbio Ion Channel -2.67075 458.1 25
Calcium uniporter regulatory subunit MCUb, mitochondrial MCUB Tdark Non-IDG -0.76467 3.88 57
Mitochondrial pyruvate carrier 1-like protein MPC1L Tdark Non-IDG 0.00000 0
Protoporphyrinogen oxidase PPOX Tchem Enzyme -2.47389 296.8 173
Protein PET100 homolog, mitochondrial PET100 Tbio Non-IDG -1.14716 12.7 11
4-hydroxybenzoate polyprenyltransferase, mitochondrial COQ2 Tbio Enzyme -2.13154 132.2 47
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial ETFDH Tbio Enzyme -1.77891 60.9 204