Development Level

Tbio 1,749 | 11,178
Tdark 1,520 | 6,569
Tchem 262 | 1,885
Tclin 134 | 612

Collection

GPCR: IDG Consortium (Targets) 86 | 126
Ion Channel: IDG Consortium (T... 32 | 99
GPCR: IDG Consortium (Complete... 10 | 25
Kinase: IDG Consortium (Target... 8 | 125
Kinase: IDG Consortium (Comple... 2 | 37

IMPC Phenotype

preweaning lethality, complete... 109 | 979
preweaning lethality, incomple... 78 | 499
abnormal behavior 54 | 298
decreased vertical activity 45 | 208
embryonic lethality prior to t... 42 | 278
enlarged heart 39 | 210
decreased bone mineral content 38 | 151
abnormal bone structure 36 | 187
increased lean body mass 35 | 172
decreased total body fat amoun... 34 | 207
increased total body fat amoun... 32 | 134
embryonic lethality prior to o... 29 | 239
abnormal heart morphology 28 | 162
decreased lean body mass 28 | 135
decreased body weight 27 | 161
abnormal embryo size 26 | 220
decreased bone mineral density 26 | 126
hyperactivity 26 | 148
hypoactivity 24 | 132
decreased circulating glucose ... 23 | 126
increased bone mineral content 23 | 108
increased or absent threshold ... 23 | 101
abnormal seminal vesicle morph... 22 | 114
decreased body length 19 | 101
improved glucose tolerance 19 | 79
increased mean corpuscular vol... 19 | 92
decreased hemoglobin content 18 | 68
increased circulating alkaline... 17 | 122
abnormal sleep behavior 15 | 70
decreased circulating serum al... 15 | 82
decreased lymphocyte cell numb... 15 | 83
decreased prepulse inhibition 15 | 82
decreased startle reflex 15 | 75
embryonic growth retardation 15 | 106
increased mean corpuscular hem... 15 | 96
abnormal eye morphology 14 | 68
decreased erythrocyte cell num... 14 | 62
decreased leukocyte cell numbe... 14 | 73
increased circulating sodium l... 14 | 71
increased monocyte cell number 14 | 63
abnormal gait 13 | 69
decreased fasted circulating g... 13 | 65
decreased grip strength 13 | 116
increased circulating HDL chol... 13 | 80
increased startle reflex 13 | 112
abnormal epididymis morphology 12 | 42
abnormal kidney morphology 12 | 65
decreased circulating triglyce... 12 | 79
decreased mean corpuscular vol... 12 | 79
increased circulating calcium ... 12 | 34
increased fasted circulating g... 12 | 76
short tibia 12 | 97
abnormal behavioral response t... 11 | 66
abnormal coat-hair pigmentatio... 11 | 64
cataract 11 | 92
decreased circulating choleste... 11 | 93
decreased circulating insulin ... 11 | 76
decreased heart weight 11 | 27
limb grasping 11 | 41
male infertility 11 | 123
decreased circulating total pr... 10 | 49
decreased red blood cell distr... 10 | 41
increased bone mineral density 10 | 72
prenatal lethality prior to he... 10 | 87
abnormal lens morphology 9 | 81
abnormal spleen morphology 9 | 55
absent startle reflex 9 | 24
enlarged epididymis 9 | 31
hydrometra 9 | 53
increased circulating triglyce... 9 | 42
increased heart weight 9 | 62
increased red blood cell distr... 9 | 34
small superior vagus ganglion 9 | 74
thrombocytopenia 9 | 56
abnormal locomotor behavior 8 | 24
abnormal testis morphology 8 | 43
decreased circulating HDL chol... 8 | 68
decreased circulating alkaline... 8 | 46
decreased circulating chloride... 8 | 30
decreased hematocrit 8 | 46
decreased mean corpuscular hem... 8 | 50
increased blood urea nitrogen ... 8 | 48
increased circulating creatini... 8 | 38
increased circulating potassiu... 8 | 29
increased hemoglobin content 8 | 45
increased mean platelet volume 8 | 45
small testis 8 | 58
abnormal neural tube closure 7 | 46
abnormal retina morphology 7 | 71
abnormal vocalization 7 | 21
decreased circulating calcium ... 7 | 36
decreased circulating creatini... 7 | 39
edema 7 | 59
impaired glucose tolerance 7 | 75
increased circulating amylase ... 7 | 25
increased circulating choleste... 7 | 66
increased circulating serum al... 7 | 22
increased heart rate 7 | 23
increased leukocyte cell numbe... 7 | 47
increased mean corpuscular hem... 7 | 36

Disease

Carcinoma 2,082 | 11,192
ovarian cancer 1,327 | 8,297
osteosarcoma 1,287 | 7,766
psoriasis 1,098 | 6,514
medulloblastoma, large-cell 1,075 | 6,086
glioblastoma 994 | 5,635
atypical teratoid / rhabdoid tumor 934 | 4,971
ependymoma 821 | 4,559
lung cancer 678 | 4,607
adult high grade glioma 676 | 3,701
Astrocytoma, Pilocytic 624 | 3,006
group 3 medulloblastoma 615 | 4,002
lung carcinoma 590 | 2,755
Breast cancer 586 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 562 | 3,204
invasive ductal carcinoma 533 | 2,867
intraductal papillary-mucinous adenoma (IPMA) 532 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 513 | 2,902
primitive neuroectodermal tumor 504 | 2,957
interstitial cystitis 500 | 2,237
non-small cell lung cancer 500 | 2,799
lung adenocarcinoma 475 | 2,627
malignant mesothelioma 455 | 3,135
oligodendroglioma 454 | 2,768
pancreatic cancer 438 | 2,322
Kidney cancer 424 | 2,548
astrocytic glioma 410 | 2,530
subependymal giant cell astrocytoma 403 | 2,230
tuberculosis 378 | 1,963
pituitary cancer 371 | 1,915
ulcerative colitis 343 | 1,765
pancreatic ductal adenocarcinoma liver metastasis 342 | 1,911
ductal carcinoma in situ 331 | 1,686
Pick disease 322 | 1,856
group 4 medulloblastoma 320 | 1,806
cystic fibrosis 307 | 1,629
breast carcinoma 285 | 1,589
diabetes mellitus 280 | 1,683
Cancer 238 | 2,388
adrenocortical carcinoma 235 | 1,385
Autosomal recessive predisposition 221 | 1,407
active Crohn's disease 204 | 882
primary pancreatic ductal adenocarcinoma 202 | 1,071
pediatric high grade glioma 199 | 1,035
cutaneous lupus erythematosus 193 | 1,016
colon cancer 188 | 1,428
astrocytoma 186 | 1,113
active ulcerative colitis 183 | 736
Multiple myeloma 182 | 1,296
Rheumatoid arthritis 176 | 1,156
Schizophrenia 175 | 1,136
acute quadriplegic myopathy 164 | 1,133
spina bifida 164 | 1,053
juvenile dermatomyositis 163 | 1,147
non primary Sjogren syndrome sicca 159 | 861
nasopharyngeal carcinoma 153 | 1,024
Atopic dermatitis 152 | 915
gastric carcinoma 144 | 781
Epilepsy 132 | 775
primary Sjogren syndrome 130 | 710
Intellectual disability 128 | 998
medulloblastoma 127 | 702
Melanoma 126 | 689
esophageal adenocarcinoma 126 | 696
Liver Cirrhosis, Experimental 119 | 733
aldosterone-producing adenoma 117 | 646
Alzheimer's disease 115 | 640
Liver cancer 115 | 589
Multiple Sclerosis 113 | 527
fibroadenoma 112 | 538
Obesity 110 | 655
acute myeloid leukemia 110 | 760
dermatomyositis 109 | 941
posterior fossa group A ependymoma 105 | 456
Skin cancer 104 | 451
mucosa-associated lymphoid tissue lymphoma 104 | 473
Bipolar Disorder 102 | 646
pancreatic carcinoma 102 | 555
Duchenne muscular dystrophy 101 | 587
progressive supranuclear palsy 101 | 656
Seizures 94 | 584
Down syndrome 88 | 480
Muscle hypotonia 82 | 562
Endometriosis 81 | 521
Dull intelligence 80 | 634
Low intelligence 80 | 634
Mental Retardation 80 | 634
Mental deficiency 80 | 634
Poor school performance 80 | 634
sonic hedgehog group medulloblastoma 76 | 459
Cognitive delay 75 | 596
Global developmental delay 75 | 596
Mental and motor retardation 75 | 596
Neurodegenerative disease 75 | 402
autosomal dominant Emery-Dreifuss muscular dystrophy 74 | 492
Short stature 71 | 514
Waldenstrons macroglobulinemia 71 | 742
hepatocellular carcinoma 71 | 536
chronic rhinosinusitis 67 | 505
Prostatic Neoplasms 66 | 472

Tissue

Endocrine System 3,150 | 18,159
Female tissues 2,977 | 17,400
Digestive Tract 2,959 | 17,369
Male tissues 2,914 | 17,142
Skin and soft tissues 2,905 | 17,230
Blood and immune system 2,847 | 16,909
Urinary Tract 2,837 | 16,678
Liver and Pancreas 2,836 | 16,750
Nervous System 2,836 | 16,725
Respiratory system 2,745 | 16,393
Cardiovascular System 2,501 | 15,192

Target Family

Non-IDG 1,929 | 12,091
Enzyme 739 | 4,145
oGPCR 410 | 421
Transporter 249 | 473
GPCR 186 | 408
Ion Channel 100 | 344
Kinase 28 | 634
Transcription Factor 19 | 1,400
Epigenetic 3 | 242
Nuclear Receptor 2 | 48

GO Component

integral component of membrane 3,665 | 3,665
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane protein 256 TMEM256 Tdark Non-IDG 0.15 0.62 15
Beta-1,4-galactosyltransferase 7 B4GALT7 Tbio Enzyme -1.56894 38.8 65
Dystroglycan DAG1 Tbio Enzyme -2.77503 560.0 254
Taste receptor type 1 member 2 TAS1R2 Tchem GPCR -2.03403 100.4 150
T-lymphocyte activation antigen CD80 CD80 Tclin Non-IDG -3.39216 2405.6 1323
E3 ubiquitin-protein ligase MARCH6 MARCH6 Tbio Enzyme -1.67925 45.8 121
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 GCNT4 Tdark Enzyme -1.56850 33.7 45
Protein FAM189A1 FAM189A1 Tdark Non-IDG 0.11 0.69 20
Protein FAM87A FAM87A Tdark Non-IDG 0.00000 0
Secreted frizzled-related protein 5 SFRP5 Tbio Non-IDG -1.81796 74.9 180