Development Level

Tbio 29 | 11,445
Tdark 12 | 6,588
Tchem 4 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal embryo size 2 | 220
decreased circulating alanine ... 2 | 47
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased lean body mass 2 | 172
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
decreased circulating choleste... 1 | 93
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating magnesiu... 1 | 10
increased grip strength 1 | 41
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
male infertility 1 | 123
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

ovarian cancer 28 | 8,520
medulloblastoma, large-cell 25 | 6,241
Carcinoma 23 | 11,493
glioblastoma 21 | 5,792
atypical teratoid / rhabdoid tumor 20 | 5,112
osteosarcoma 20 | 7,950
psoriasis 13 | 6,694
ependymoma 11 | 4,679
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Astrocytoma, Pilocytic 9 | 3,081
Breast cancer 9 | 3,578
Rheumatoid arthritis 8 | 1,191
adult high grade glioma 8 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
lung adenocarcinoma 8 | 2,716
malignant mesothelioma 8 | 3,232
oligodendroglioma 8 | 2,850
astrocytic glioma 7 | 2,597
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
primitive neuroectodermal tumor 7 | 3,035
Pick disease 6 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung cancer 6 | 4,740
pituitary cancer 6 | 1,972
active Crohn's disease 5 | 922
active ulcerative colitis 5 | 764
interstitial cystitis 5 | 2,312
lung carcinoma 5 | 2,843
non-small cell lung cancer 5 | 2,890
tuberculosis 5 | 2,010
ulcerative colitis 5 | 1,819
Autosomal recessive predisposition 4 | 1,442
astrocytoma 4 | 1,146
group 4 medulloblastoma 4 | 1,855
invasive ductal carcinoma 4 | 2,951
Cognitive delay 3 | 608
Epilepsy 3 | 792
Global developmental delay 3 | 608
Kidney cancer 3 | 2,613
Melanoma 3 | 711
Mental and motor retardation 3 | 608
Multiple myeloma 3 | 1,332
Muscular dystrophy 3 | 75
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
gastric carcinoma 3 | 807
juvenile dermatomyositis 3 | 1,187
pediatric high grade glioma 3 | 1,064
primary Sjogren syndrome 3 | 735
progressive supranuclear palsy 3 | 676
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
Agenesis of corpus callosum 2 | 83
Alagille syndrome 2 | 15
Cancer 2 | 2,499
Cerebellar Hypoplasia 2 | 61
Chronic Lymphocytic Leukemia 2 | 262
Cobblestone Lissencephaly 2 | 8
Congenital muscular dystrophy 2 | 29
Creatine phosphokinase serum increased 2 | 110
Dandy-Walker Syndrome 2 | 39
Dull intelligence 2 | 645
Elevated creatine kinase 2 | 110
Farber lipogranulomatosis 2 | 9
Hydrocephalus 2 | 152
Hypoplasia of corpus callosum 2 | 90
Hypoplasia of the brainstem 2 | 22
Hypotonia, severe 2 | 33
Intellectual disability 2 | 1,016
Kyphosis deformity of spine 2 | 114
Lissencephaly 2 | 69
Liver neoplasms 2 | 130
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Muscle biopsy shows dystrophic changes 2 | 39
Muscular Dystrophy-Dystroglycanopathy (Congenital With Brain and Eye Anomalies), Type A, 1 2 | 6
Poor school performance 2 | 645
Posterior amorphous corneal dystrophy 2 | 9
Retinal Dysplasia 2 | 11
Seizures 2 | 596
Short stature 2 | 531
Small head 2 | 374
Waldenstrons macroglobulinemia 2 | 765
Walker-Warburg congenital muscular dystrophy 2 | 14
Walker-Warburg syndrome 2 | 20
Weight Gain 2 | 100
aldosterone-producing adenoma 2 | 665
colon cancer 2 | 1,478
diabetes mellitus 2 | 1,728
fibroadenoma 2 | 559
hepatocellular carcinoma 2 | 547
medulloblastoma 2 | 720
pancreatic cancer 2 | 2,398
tuberculosis and treatment for 3 months 2 | 179
Epilepsies, Myoclonic 1 | 32
Melancholia 1 | 10
Splenic abscess 1 | 2
Wolcott-Rallison syndrome 1 | 10

Tissue

Endocrine System 43 | 18,159
Nervous System 43 | 16,725
Cardiovascular System 42 | 15,192
Digestive Tract 42 | 17,369
Female tissues 42 | 17,400
Liver and Pancreas 42 | 16,750
Male tissues 42 | 17,142
Respiratory system 42 | 16,393
Skin and soft tissues 42 | 17,230
Urinary Tract 42 | 16,678
Blood and immune system 41 | 16,909

Target Family

Enzyme 25 | 4,145
Non-IDG 14 | 12,091
Transporter 5 | 473
Transcription Factor 1 | 1,400

GO Component

integral component of Golgi me... 45 | 45
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,3-N-acetylglucosaminyltransferase radical fringe RFNG Tdark Enzyme -0.37913 1.57 92
UbiA prenyltransferase domain-containing protein 1 UBIAD1 Tbio Enzyme -1.59893 42.5 50
Phosphatidylcholine:ceramide cholinephosphotransferase 1 SGMS1 Tchem Enzyme -1.61164 41.6 0
Alkaline ceramidase 3 ACER3 Tbio Enzyme -2.07938 117.1 95
Protein CASP CUX1 Tbio Transcription Factor -2.43505 487.9 295
Golgi apparatus membrane protein TVP23 homolog B TVP23B Tdark Non-IDG 0.15 1.13 24
Protein unc-50 homolog UNC50 Tdark Non-IDG -0.96776 11.0 38
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe LFNG Tbio Enzyme -1.50535 29.8 220
UDP-xylose and UDP-N-acetylglucosamine transporter SLC35B4 Tbio Transporter -1.26168 16.6 19
Golgi-associated olfactory signaling regulator GFY Tdark Non-IDG -1.10551 13.3 0