Development Level

Tbio 17 | 11,445
Tchem 5 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased total body fat amoun... 4 | 207
increased lean body mass 2 | 172
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
absent spleen 1 | 3
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased leukocyte cell numbe... 1 | 73
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
fusion of vertebral arches 1 | 7
increased body length 1 | 32
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating amylase ... 1 | 25
increased circulating creatini... 1 | 38
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

Carcinoma 18 | 11,493
osteosarcoma 14 | 7,950
ovarian cancer 12 | 8,520
Cancer 10 | 2,499
psoriasis 10 | 6,694
Kabuki syndrome 8 | 27
Kidney cancer 8 | 2,613
medulloblastoma, large-cell 8 | 6,241
atypical teratoid / rhabdoid tumor 7 | 5,112
glioblastoma 7 | 5,792
group 3 medulloblastoma 6 | 4,104
lung cancer 6 | 4,740
Breast cancer 5 | 3,578
Intellectual disability 5 | 1,016
malignant mesothelioma 5 | 3,232
oligodendroglioma 5 | 2,850
Bladder Neoplasm 4 | 112
Liver cancer 4 | 604
Pick disease 4 | 1,894
Schizophrenia 4 | 1,160
Urinary Bladder Neoplasms 4 | 114
adrenocortical carcinoma 4 | 1,428
astrocytic glioma 4 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
primitive neuroectodermal tumor 4 | 3,035
Alzheimer's disease 3 | 658
Birthmark 3 | 35
Byzanthine arch palate 3 | 194
Cafe-au-Lait Spots 3 | 37
Carcinoma, Hepatocellular 3 | 228
Carcinoma, Transitional Cell 3 | 32
Dull intelligence 3 | 645
Epilepsy 3 | 792
Esophageal Squamous Cell Carcinoma 3 | 77
Failure to gain weight 3 | 365
Leukemia 3 | 104
Liver carcinoma 3 | 240
Low intelligence 3 | 645
Lymphoid leukemia 3 | 160
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Muscle hypotonia 3 | 571
Pediatric failure to thrive 3 | 365
Poor school performance 3 | 645
Seizures 3 | 596
Short middle phalanges 3 | 12
Short stature 3 | 531
Squamous cell carcinoma of esophagus 3 | 77
Strabismus 3 | 270
ependymoma 3 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Adenoid Cystic Carcinoma 2 | 99
Atrial Septal Defects 2 | 85
Autoimmune thrombocytopenia 2 | 22
Blepharoptosis 2 | 231
Blue sclera 2 | 32
Broad flat nasal bridge 2 | 236
Carcinoma, Adenoid Cystic 2 | 99
Cerebral atrophy 2 | 178
Conductive hearing loss 2 | 123
Congenital deafness 2 | 185
DOID:2627 2 | 94
Deafness 2 | 198
Depressed nasal tip 2 | 11
Dilated ventricles (finding) 2 | 121
Endometrial cancer 2 | 311
Hearing Loss, Partial 2 | 185
Hip Dislocation, Congenital 2 | 48
Hirsutism 2 | 47
Hypodontia 2 | 81
Idiopathic thrombocytopenia 2 | 22
Immune thrombocytopenic purpura 2 | 24
Joint hyperflexibility 2 | 78
Large auricle 2 | 87
Large dysplastic ears 2 | 87
Large intestine cancer 2 | 126
Large pinnae 2 | 87
Large prominent ears 2 | 87
Large protruding ears 2 | 87
Large, floppy ears 2 | 87
Leukemia, Myelocytic, Acute 2 | 120
Long eyelashes 2 | 37
Macrotia 2 | 87
Malabsorption 2 | 82
Melanoma 2 | 711
Nasal bridge wide 2 | 236
Neurodevelopmental Disorders 2 | 70
Prominent ear 2 | 56
Protruding ears 2 | 56
Range of joint movement increased 2 | 32
Recurrent infections 2 | 48
Sensorineural Hearing Loss (disorder) 2 | 284
Stomach Neoplasms 2 | 300
hearing impairment 2 | 199

Tissue

Blood and immune system 23 | 16,909
Cardiovascular System 23 | 15,192
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678

Target Family

Epigenetic 11 | 242
Non-IDG 8 | 12,091
TF/Epigenetic 2 | 38
Enzyme 1 | 4,145
Transcription Factor 1 | 1,400

GO Component

histone methyltransferase comp... 23 | 23
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
PAXIP1-associated glutamate-rich protein 1 PAGR1 Tbio Non-IDG -1.03602 8.61 59
PR domain zinc finger protein 4 PRDM4 Tbio TF/Epigenetic -0.87918 7.84 221
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431
Histone-lysine N-methyltransferase SETD1A SETD1A Tbio Epigenetic -2.57679 365.2 125
Histone-lysine N-methyltransferase 2B KMT2B Tbio Epigenetic -1.93899 84.8 153
Menin MEN1 Tchem Non-IDG -3.23460 1803.0 382
Protein arginine N-methyltransferase 5 PRMT5 Tchem Epigenetic -2.18391 171.0 447
Histone-lysine N-methyltransferase 2C KMT2C Tbio Epigenetic -1.87625 76.5 68
Chromobox protein homolog 5 CBX5 Tbio Epigenetic -1.90801 83.4 624
Set1/Ash2 histone methyltransferase complex subunit ASH2 ASH2L Tbio Enzyme -1.56543 33.7 261