Development Level

Tbio 20 | 11,651
Tchem 3 | 1,388
Tclin 1 | 612

IMPC Phenotype

increased circulating alkaline... 2 | 122
increased circulating triglyce... 2 | 42
abnormal coat- hair morphology 1 | 19
abnormal embryo size 1 | 220
abnormal retina morphology 1 | 71
abnormal tooth morphology 1 | 24
decreased circulating HDL chol... 1 | 68
decreased circulating bilirubi... 1 | 19
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased food intake 1 | 13
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Atherosclerosis 15 | 291
Coronary artery disease 14 | 268
diabetes mellitus 12 | 1,728
psoriasis 12 | 6,694
Carcinoma 11 | 11,493
Lipid metabolism disorder 11 | 114
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
ovarian cancer 9 | 8,520
Hypercholesterolemia, Familial 8 | 23
Kidney disease 8 | 430
Obesity 8 | 678
ependymoma 8 | 4,679
lung cancer 8 | 4,740
oligodendroglioma 8 | 2,850
osteosarcoma 8 | 7,950
Amyloidosis 7 | 67
Cardiovascular system disease 7 | 246
Hyperlipoproteinemia Type II 7 | 12
Schizophrenia 7 | 1,160
invasive ductal carcinoma 7 | 2,951
lung carcinoma 7 | 2,843
Cerebrovascular disease 6 | 238
Hypertension 6 | 396
adrenocortical carcinoma 6 | 1,428
astrocytic glioma 6 | 2,597
malignant mesothelioma 6 | 3,232
medulloblastoma, large-cell 6 | 6,241
ductal carcinoma in situ 5 | 1,745
glioblastoma 5 | 5,792
group 3 medulloblastoma 5 | 4,104
subependymal giant cell astrocytoma 5 | 2,287
Age related macular degeneration 4 | 72
Alzheimer's disease 4 | 658
Anemia 4 | 365
Autosomal recessive predisposition 4 | 1,442
Cancer 4 | 2,499
Chemical and Drug Induced Liver Injury 4 | 195
Down syndrome 4 | 499
High density lipoprotein decreased 4 | 10
Hypercholesterolemia 4 | 44
Hyperlipidemia 4 | 43
Hypertriglyceridemia result 4 | 37
Hypoalphalipoproteinemias 4 | 10
Macular degeneration 4 | 65
Metabolic syndrome X 4 | 52
Splenomegaly 4 | 190
Type 2 diabetes mellitus 4 | 272
Vascular disease 4 | 319
atypical teratoid / rhabdoid tumor 4 | 5,112
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
juvenile dermatomyositis 4 | 1,187
non-small cell lung cancer 4 | 2,890
Amyotrophic lateral sclerosis 3 | 451
Arcus Senilis 3 | 11
Bipolar Disorder 3 | 666
Breast cancer 3 | 3,578
Cardiovascular Diseases 3 | 59
Clouding of corneal stroma 3 | 50
Corneal Opacity 3 | 53
Dyslipidemias 3 | 27
Hepatomegaly 3 | 285
Hypercholesterolemia, Autosomal Dominant, Type B 3 | 5
Hyperlipidemias 3 | 17
Hyperlipoproteinemia Type IIa 3 | 11
Hyperlipoproteinemias 3 | 5
Hypertensive disease 3 | 292
Hypertriglyceridemia 3 | 17
Liver Cirrhosis, Experimental 3 | 769
Lung Neoplasms 3 | 232
Nerve Degeneration 3 | 121
Neurodegenerative disease 3 | 414
Pediatric Obesity 3 | 4
Pick disease 3 | 1,894
Proteinuria 3 | 144
Rheumatoid arthritis 3 | 1,191
acute quadriplegic myopathy 3 | 1,158
esophageal adenocarcinoma 3 | 737
head and neck cancer and chronic obstructive pulmonary disease 3 | 239
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
nephrosclerosis 3 | 333
pediatric high grade glioma 3 | 1,064
Cerebrovascular accident 2 | 63
Cholestasis 2 | 155
Cognition Disorders 2 | 32
Dementia 2 | 175
Heart disease 2 | 306
Hemoglobin low 2 | 124
Kidney Failure 2 | 111
Parkinson's disease 2 | 392
Polycystic ovary syndrome 2 | 360
Renal Insufficiency 2 | 90
Renal failure in adulthood 2 | 76
Seizures 2 | 596
Toxic encephalopathy 2 | 141
active ulcerative colitis 2 | 764
breast carcinoma 2 | 1,638
nasopharyngeal carcinoma 2 | 1,058
tuberculosis 2 | 2,010

Tissue

Digestive Tract 24 | 17,369
Endocrine System 24 | 18,159
Female tissues 24 | 17,400
Liver and Pancreas 24 | 16,750
Male tissues 23 | 17,142
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678
Blood and immune system 22 | 16,909
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Cardiovascular System 18 | 15,192

Target Family

Non-IDG 20 | 12,091
Enzyme 3 | 4,145
Transporter 1 | 473

GO Component

high-density lipoprotein parti... 24 | 24
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388
Apolipoprotein F APOF Tbio Non-IDG -1.45156 33.3 232
Beta-2-glycoprotein 1 APOH Tbio Non-IDG -3.18007 1422.8 342
Serum paraoxonase/arylesterase 1 PON1 Tbio Enzyme -3.39345 2648.8 361
Apolipoprotein E APOE Tbio Non-IDG -4.20176 15904.9 976
Apolipoprotein A-II APOA2 Tbio Non-IDG -2.81123 595.2 420
Apolipoprotein A-I APOA1 Tbio Non-IDG -3.62534 3592.8 1151
Hepatic triacylglycerol lipase LIPC Tchem Enzyme -2.56840 389.0 258
Apolipoprotein L1 APOL1 Tbio Non-IDG -2.53525 361.2 280
Serum amyloid A-4 protein SAA4 Tbio Non-IDG -1.80199 61.7 157