Development Level

Tbio 57 | 11,651
Tchem 7 | 1,388
Tdark 4 | 6,593
Tclin 1 | 612

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
preweaning lethality, complete... 4 | 979
abnormal behavior 3 | 298
abnormal sleep behavior 2 | 70
hyperactivity 2 | 148
small testis 2 | 58
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal hair growth 1 | 10
abnormal iris morphology 1 | 13
abnormal iris pigmentation 1 | 4
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal stomach morphology 1 | 10
abnormal testis morphology 1 | 43
absent urinary bladder 1 | 1
absent vibrissae 1 | 12
decreased body length 1 | 101
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased grip strength 1 | 116
decreased spleen weight 1 | 10
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
female infertility 1 | 60
hydrometra 1 | 53
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased coping response 1 | 4
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased urine magnesium leve... 1 | 2
increased vertical activity 1 | 24
short tibia 1 | 97
thrombocytopenia 1 | 56

Disease

Carcinoma 54 | 11,493
ovarian cancer 47 | 8,520
medulloblastoma, large-cell 41 | 6,241
glioblastoma 40 | 5,792
ependymoma 38 | 4,679
osteosarcoma 38 | 7,950
atypical teratoid / rhabdoid tumor 35 | 5,112
psoriasis 34 | 6,694
lung cancer 30 | 4,740
Breast cancer 28 | 3,578
non-small cell lung cancer 25 | 2,890
Astrocytoma, Pilocytic 24 | 3,081
Cancer 24 | 2,499
adult high grade glioma 23 | 3,801
group 3 medulloblastoma 23 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,955
lung carcinoma 21 | 2,843
malignant mesothelioma 19 | 3,232
lung adenocarcinoma 18 | 2,716
primitive neuroectodermal tumor 18 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
oligodendroglioma 17 | 2,850
Kidney cancer 16 | 2,613
invasive ductal carcinoma 16 | 2,951
pancreatic cancer 16 | 2,398
astrocytic glioma 15 | 2,597
cystic fibrosis 15 | 1,696
group 4 medulloblastoma 15 | 1,855
tuberculosis 15 | 2,010
astrocytoma 14 | 1,146
interstitial cystitis 14 | 2,312
juvenile dermatomyositis 14 | 1,187
subependymal giant cell astrocytoma 14 | 2,287
breast carcinoma 13 | 1,638
colon cancer 13 | 1,478
ulcerative colitis 12 | 1,819
Pick disease 11 | 1,894
diabetes mellitus 11 | 1,728
ductal carcinoma in situ 11 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Duchenne muscular dystrophy 10 | 601
acute quadriplegic myopathy 10 | 1,158
dermatomyositis 10 | 966
pediatric high grade glioma 10 | 1,064
pituitary cancer 10 | 1,972
Autosomal recessive predisposition 9 | 1,442
Amyotrophic lateral sclerosis 8 | 451
Liver Cirrhosis, Experimental 8 | 769
Liver cancer 8 | 604
adrenocortical carcinoma 8 | 1,428
esophageal adenocarcinoma 8 | 737
Muscle hypotonia 7 | 571
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
gastric carcinoma 7 | 807
primary pancreatic ductal adenocarcinoma 7 | 1,109
spina bifida 7 | 1,074
Endometriosis 6 | 540
Multiple myeloma 6 | 1,332
Myopathy 6 | 185
Neuropathy 6 | 261
Schizophrenia 6 | 1,160
cutaneous lupus erythematosus 6 | 1,057
Becker muscular dystrophy 5 | 191
Cardiomyopathy 5 | 116
Cardiomyopathy, Dilated 5 | 83
Down syndrome 5 | 499
Intellectual disability 5 | 1,016
Polyhydramnios 5 | 108
Rheumatoid arthritis 5 | 1,191
active Crohn's disease 5 | 922
active ulcerative colitis 5 | 764
aldosterone-producing adenoma 5 | 665
medulloblastoma 5 | 720
nasopharyngeal carcinoma 5 | 1,058
primary Sjogren syndrome 5 | 735
progressive supranuclear palsy 5 | 676
Asthma 4 | 385
Big calvaria 4 | 147
Chronic Lymphocytic Leukemia 4 | 262
Cognitive delay 4 | 608
Creatine phosphokinase serum increased 4 | 110
Dilated cardiomyopathy 4 | 56
Dull intelligence 4 | 645
Elevated creatine kinase 4 | 110
Endometrial cancer 4 | 311
Global developmental delay 4 | 608
Hydrolethalus syndrome 4 | 128
Increased head circumference 4 | 147
Increased size of cranium 4 | 147
Increased size of skull 4 | 147
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Neurodegenerative disease 4 | 414
Nonsyndromic deafness 4 | 142
Poor school performance 4 | 645
Prenatal onset 4 | 139
chronic rhinosinusitis 4 | 512

Tissue

Female tissues 68 | 17,400
Blood and immune system 67 | 16,909
Digestive Tract 67 | 17,369
Endocrine System 67 | 18,159
Liver and Pancreas 67 | 16,750
Male tissues 67 | 17,142
Respiratory system 67 | 16,393
Skin and soft tissues 67 | 17,230
Urinary Tract 66 | 16,678
Nervous System 64 | 16,725
Cardiovascular System 63 | 15,192

Target Family

Non-IDG 54 | 12,091
Enzyme 9 | 4,145
Kinase 3 | 634
GPCR 1 | 408
Ion Channel 1 | 344
Transporter 1 | 473

GO Component

filopodium 69 | 69
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ezrin EZR Tbio Non-IDG -2.99865 981.3 1088
Cyclin-dependent-like kinase 5 CDK5 Tchem Kinase -3.06393 1238.4 694
Twinfilin-1 TWF1 Tbio Non-IDG -1.08655 12.4 211
Podoplanin PDPN Tbio Non-IDG -3.34579 2142.9 847
Abl interactor 2 ABI2 Tbio Non-IDG -1.37075 21.4 168
Lymphocyte antigen 6 complex locus protein G6d LY6G6D Tbio Non-IDG -1.42490 25.7 92
Myotubularin MTM1 Tbio Enzyme -2.72507 527.3 235
Ephrin type-A receptor 4 EPHA4 Tchem Kinase -2.37243 255.5 495
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Shootin-1 SHTN1 Tdark Non-IDG -1.03153 10.3 23