Development Level

Tbio 79 | 11,445
Tchem 34 | 1,598
Tclin 6 | 613
Tdark 5 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 10 | 979
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
decreased caudal vertebrae num... 2 | 53
decreased circulating choleste... 2 | 93
short tibia 2 | 97
abnormal QT variability 1 | 10
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
cataract 1 | 92
decreased circulating aspartat... 1 | 34
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased fasted circulating g... 1 | 65
decreased fluid intake 1 | 3
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased body temperature 1 | 9
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
long tibia 1 | 25
male infertility 1 | 123
premature death 1 | 5
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74

Disease

ovarian cancer 94 | 8,520
Carcinoma 76 | 11,493
osteosarcoma 63 | 7,950
lung cancer 62 | 4,740
psoriasis 52 | 6,694
glioblastoma 42 | 5,792
Cancer 41 | 2,499
medulloblastoma, large-cell 39 | 6,241
atypical teratoid / rhabdoid tumor 37 | 5,112
tuberculosis 37 | 2,010
Breast cancer 34 | 3,578
pancreatic cancer 34 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 33 | 3,291
Multiple myeloma 32 | 1,332
group 3 medulloblastoma 31 | 4,104
invasive ductal carcinoma 31 | 2,951
non-small cell lung cancer 31 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 31 | 1,962
ependymoma 30 | 4,679
Waldenstrons macroglobulinemia 29 | 765
lung adenocarcinoma 29 | 2,716
subependymal giant cell astrocytoma 28 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 27 | 2,989
malignant mesothelioma 27 | 3,232
diabetes mellitus 25 | 1,728
adult high grade glioma 24 | 3,801
interstitial cystitis 24 | 2,312
Astrocytoma, Pilocytic 23 | 3,081
astrocytoma 23 | 1,146
lung carcinoma 23 | 2,843
dermatomyositis 21 | 966
Autosomal recessive predisposition 20 | 1,442
juvenile dermatomyositis 20 | 1,187
oligodendroglioma 19 | 2,850
primary pancreatic ductal adenocarcinoma 19 | 1,109
cutaneous lupus erythematosus 18 | 1,057
ulcerative colitis 18 | 1,819
acute quadriplegic myopathy 17 | 1,158
breast carcinoma 17 | 1,638
Alzheimer's disease 16 | 658
adrenocortical carcinoma 16 | 1,428
esophageal adenocarcinoma 16 | 737
Liver Cirrhosis, Experimental 15 | 769
mucosa-associated lymphoid tissue lymphoma 15 | 484
astrocytic glioma 14 | 2,597
ductal carcinoma in situ 14 | 1,745
group 4 medulloblastoma 14 | 1,855
Kidney cancer 13 | 2,613
Rheumatoid arthritis 13 | 1,191
Schizophrenia 13 | 1,160
cystic fibrosis 13 | 1,696
primitive neuroectodermal tumor 13 | 3,035
Intellectual disability 12 | 1,016
Neoplasm Invasiveness 12 | 161
Pick disease 12 | 1,894
colon cancer 12 | 1,478
pituitary cancer 12 | 1,972
Breast Neoplasms 11 | 445
Mammary Neoplasms 11 | 425
Osteoporosis 11 | 363
Vascular disease 11 | 319
Arthritis 10 | 290
Atopic dermatitis 10 | 952
Dull intelligence 10 | 645
HIV Infections 10 | 102
Hepatomegaly 10 | 285
Low intelligence 10 | 645
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Poor school performance 10 | 645
gastric carcinoma 10 | 807
Duchenne muscular dystrophy 9 | 601
Neoplasm Metastasis 9 | 168
Obesity 9 | 678
Short stature 9 | 531
Splenomegaly 9 | 190
hepatocellular carcinoma 9 | 547
non primary Sjogren syndrome sicca 9 | 891
pancreatic carcinoma 9 | 562
primary Sjogren syndrome 9 | 735
Atherosclerosis 8 | 291
Carcinoma, Hepatocellular 8 | 228
Liver carcinoma 8 | 240
Prostatic Neoplasms 8 | 495
Stomach Neoplasms 8 | 300
fibroadenoma 8 | 559
periodontitis 8 | 293
posterior fossa group A ependymoma 8 | 468
Asthma 7 | 385
Bipolar Disorder 7 | 666
Cardiomyopathies 7 | 110
Hypertension 7 | 396
Liver diseases 7 | 87
Neurodegenerative disease 7 | 414
Squamous cell carcinoma 7 | 129
chronic lymphosyte leukemia 7 | 204
gastric cancer 7 | 459
interstitial lung disease 7 | 298
pediatric high grade glioma 7 | 1,064

Tissue

Blood and immune system 124 | 16,909
Digestive Tract 124 | 17,369
Endocrine System 124 | 18,159
Female tissues 124 | 17,400
Liver and Pancreas 124 | 16,750
Male tissues 124 | 17,142
Skin and soft tissues 124 | 17,230
Nervous System 123 | 16,725
Respiratory system 123 | 16,393
Urinary Tract 123 | 16,678
Cardiovascular System 122 | 15,192

Target Family

Enzyme 59 | 4,145
Non-IDG 56 | 12,091
Kinase 8 | 634
Transcription Factor 1 | 1,400

GO Component

ficolin-1-rich granule lumen 124 | 124
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Multiple myeloma tumor-associated protein 2 C1orf35 Tdark Non-IDG 0.00000 1.00 39
Deoxyribose-phosphate aldolase DERA Tbio Enzyme -2.21374 155.0 69
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.74914 5601.8 1083
Cystatin-C CST3 Tbio Non-IDG -3.52815 3278.8 866
ATP-citrate synthase ACLY Tchem Enzyme -2.82704 654.3 332
Signal recognition particle 14 kDa protein SRP14 Tbio Non-IDG -1.25810 14.5 106
Calmodulin-like protein 5 CALML5 Tbio Non-IDG -1.32968 24.4 111
Dynein light chain Tctex-type 1 DYNLT1 Tbio Non-IDG -2.30647 213.2 45
Actin-related protein 10 ACTR10 Tbio Non-IDG -0.75524 5.22 61
Actin-related protein 2 ACTR2 Tbio Non-IDG -1.88412 78.5 211