Development Level

Tbio 98 | 11,445
Tchem 14 | 1,598
Tdark 14 | 6,588
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 13 | 979
embryonic lethality prior to t... 5 | 278
preweaning lethality, incomple... 5 | 499
abnormal embryo size 3 | 220
abnormal behavior 2 | 298
abnormal heart morphology 2 | 162
decreased circulating sodium l... 2 | 22
embryonic growth retardation 2 | 106
enlarged heart 2 | 210
abnormal bone structure 1 | 187
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal locomotor behavior 1 | 24
abnormal maxilla morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal posture 1 | 2
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal tooth morphology 1 | 24
anophthalmia 1 | 33
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased cornea thickness 1 | 2
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged pancreas 1 | 2
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased aggression 1 | 4
increased bone mineral content 1 | 108
increased cardiac muscle contr... 1 | 8
increased caudal vertebrae num... 1 | 7
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating insulin ... 1 | 3
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged QRS complex duration 1 | 8
short tibia 1 | 97

Disease

Carcinoma 90 | 11,493
ovarian cancer 67 | 8,520
osteosarcoma 64 | 7,950
lung cancer 51 | 4,740
medulloblastoma, large-cell 51 | 6,241
psoriasis 50 | 6,694
glioblastoma 43 | 5,792
group 3 medulloblastoma 39 | 4,104
atypical teratoid / rhabdoid tumor 36 | 5,112
adult high grade glioma 33 | 3,801
malignant mesothelioma 31 | 3,232
ependymoma 30 | 4,679
Cancer 29 | 2,499
Breast cancer 27 | 3,578
primitive neuroectodermal tumor 26 | 3,035
invasive ductal carcinoma 25 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
lung carcinoma 23 | 2,843
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
Astrocytoma, Pilocytic 19 | 3,081
lung adenocarcinoma 19 | 2,716
subependymal giant cell astrocytoma 18 | 2,287
non-small cell lung cancer 17 | 2,890
oligodendroglioma 17 | 2,850
astrocytic glioma 15 | 2,597
colon cancer 15 | 1,478
group 4 medulloblastoma 15 | 1,855
juvenile dermatomyositis 15 | 1,187
acute quadriplegic myopathy 14 | 1,158
cutaneous lupus erythematosus 14 | 1,057
tuberculosis 14 | 2,010
Kidney cancer 13 | 2,613
Multiple myeloma 13 | 1,332
interstitial cystitis 13 | 2,312
pancreatic cancer 13 | 2,398
pituitary cancer 12 | 1,972
Waldenstrons macroglobulinemia 11 | 765
astrocytoma 11 | 1,146
breast carcinoma 11 | 1,638
cystic fibrosis 11 | 1,696
diabetes mellitus 11 | 1,728
Pick disease 10 | 1,894
ductal carcinoma in situ 10 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
primary Sjogren syndrome 10 | 735
Amyotrophic lateral sclerosis 9 | 451
Cognitive delay 9 | 608
Global developmental delay 9 | 608
Mental and motor retardation 9 | 608
active Crohn's disease 9 | 922
pediatric high grade glioma 9 | 1,064
Autosomal recessive predisposition 8 | 1,442
Intellectual disability 8 | 1,016
Prostatic Neoplasms 8 | 495
Rheumatoid arthritis 8 | 1,191
gastric carcinoma 8 | 807
ulcerative colitis 8 | 1,819
adrenocortical carcinoma 7 | 1,428
aldosterone-producing adenoma 7 | 665
nasopharyngeal carcinoma 7 | 1,058
primary pancreatic ductal adenocarcinoma 7 | 1,109
Liver Cirrhosis, Experimental 6 | 769
Schizophrenia 6 | 1,160
active ulcerative colitis 6 | 764
dermatomyositis 6 | 966
spina bifida 6 | 1,074
Adenocarcinoma of lung 5 | 142
Atopic dermatitis 5 | 952
Cryptorchidism 5 | 296
Disease Models, Animal 5 | 155
Duchenne muscular dystrophy 5 | 601
Dull intelligence 5 | 645
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Muscle hypotonia 5 | 571
Obesity 5 | 678
Poor school performance 5 | 645
Short stature 5 | 531
Small head 5 | 374
Systemic scleroderma 5 | 60
acute myeloid leukemia 5 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
esophageal adenocarcinoma 5 | 737
inflammatory breast cancer 5 | 286
interstitial lung disease 5 | 298
medulloblastoma 5 | 720
non primary Sjogren syndrome sicca 5 | 891
sonic hedgehog group medulloblastoma 5 | 467
Broad flat nasal bridge 4 | 236
Crohn's disease 4 | 321
Epilepsy 4 | 792
Failure to gain weight 4 | 365
Fetal Growth Retardation 4 | 189
Infant, Small for Gestational Age 4 | 176
Intrauterine retardation 4 | 176
Strabismus 4 | 270
mucosa-associated lymphoid tissue lymphoma 4 | 484
progressive supranuclear palsy 4 | 676

Tissue

Female tissues 128 | 17,400
Digestive Tract 127 | 17,369
Endocrine System 127 | 18,159
Male tissues 127 | 17,142
Skin and soft tissues 127 | 17,230
Blood and immune system 126 | 16,909
Liver and Pancreas 126 | 16,750
Nervous System 126 | 16,725
Respiratory system 126 | 16,393
Urinary Tract 126 | 16,678
Cardiovascular System 123 | 15,192

Target Family

Non-IDG 72 | 12,091
Enzyme 24 | 4,145
Transcription Factor 19 | 1,400
Kinase 7 | 634
Epigenetic 3 | 242
Ion Channel 1 | 344
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

GO Component

fibrillar center 128 | 128
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitochondrial import inner membrane translocase subunit Tim13 TIMM13 Tbio Enzyme -1.90930 75.7 32
Leucine-rich repeat-containing protein 26 LRRC26 Tbio Ion Channel -1.02699 11.3 81
Paraspeckle component 1 PSPC1 Tbio Non-IDG -1.75415 48.3 19
Methylthioribose-1-phosphate isomerase MRI1 Tbio Enzyme -2.37285 221.6 146
Ribosomal protein S6 kinase alpha-6 RPS6KA6 Tchem Kinase -1.26563 21.6 158
Juxtaposed with another zinc finger protein 1 JAZF1 Tbio Non-IDG -1.61585 42.8 94
Sestrin-1 SESN1 Tbio Non-IDG -1.95681 82.0 172
Y-box-binding protein 2 YBX2 Tbio Transcription Factor -1.99119 94.8 236
Krueppel-like factor 6 KLF6 Tbio Transcription Factor -2.37304 253.6 161
BTB/POZ domain-containing protein 10 BTBD10 Tbio Non-IDG -0.47192 5.30 152