Development Level

Tbio 33 | 11,445
Tchem 26 | 1,598
Tclin 13 | 613
Tdark 1 | 6,588

Collection

Ion Channel: IDG Consortium (T... 2 | 99
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

hypoactivity 5 | 132
preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal seminal vesicle morph... 3 | 114
decreased circulating HDL chol... 3 | 68
decreased lymphocyte cell numb... 3 | 83
increased monocyte cell number 3 | 63
abnormal bone structure 2 | 187
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating LDL chol... 2 | 38
decreased circulating choleste... 2 | 93
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
abnormal coat-hair pigmentatio... 1 | 64
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal maxilla morphology 1 | 17
abnormal retinal inner nuclear... 1 | 8
abnormal sensory capabilities-... 1 | 8
abnormal testis morphology 1 | 43
abnormal urinary bladder morph... 1 | 11
abnormal vertebrae morphology 1 | 18
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating potassiu... 1 | 20
decreased eosinophil cell numb... 1 | 24
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged seminal vesicle 1 | 10
enlarged spleen 1 | 41
hydrometra 1 | 53
increased CD4-positive, alpha ... 1 | 4
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased spleen weight 1 | 10
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
increased total retina thickne... 1 | 4
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Carcinoma 60 | 11,493
osteosarcoma 55 | 7,950
ovarian cancer 46 | 8,520
medulloblastoma, large-cell 38 | 6,241
Cancer 37 | 2,499
glioblastoma 33 | 5,792
psoriasis 31 | 6,694
ependymoma 29 | 4,679
atypical teratoid / rhabdoid tumor 28 | 5,112
oligodendroglioma 24 | 2,850
adult high grade glioma 23 | 3,801
invasive ductal carcinoma 23 | 2,951
Astrocytoma, Pilocytic 22 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
lung cancer 22 | 4,740
lung carcinoma 22 | 2,843
pancreatic cancer 22 | 2,398
Kidney cancer 21 | 2,613
group 3 medulloblastoma 21 | 4,104
interstitial cystitis 21 | 2,312
non-small cell lung cancer 21 | 2,890
subependymal giant cell astrocytoma 20 | 2,287
Breast cancer 19 | 3,578
primitive neuroectodermal tumor 19 | 3,035
Blastic phase chronic myeloid leukemia 18 | 58
Chronic Myelocytic Leukemia Accelerated Phase 18 | 59
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
Chronic phase chronic myeloid leukemia 16 | 45
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 16 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 16 | 47
juvenile dermatomyositis 16 | 1,187
malignant mesothelioma 16 | 3,232
ulcerative colitis 15 | 1,819
lung adenocarcinoma 14 | 2,716
tuberculosis 14 | 2,010
Pick disease 13 | 1,894
Rheumatoid arthritis 13 | 1,191
astrocytic glioma 13 | 2,597
ductal carcinoma in situ 13 | 1,745
primary Sjogren syndrome 12 | 735
group 4 medulloblastoma 11 | 1,855
astrocytoma 10 | 1,146
cutaneous lupus erythematosus 10 | 1,057
pituitary cancer 10 | 1,972
adrenocortical carcinoma 9 | 1,428
cystic fibrosis 9 | 1,696
diabetes mellitus 9 | 1,728
Atopic dermatitis 8 | 952
Liver Cirrhosis, Experimental 8 | 769
breast carcinoma 8 | 1,638
colon cancer 8 | 1,478
dermatomyositis 8 | 966
pancreatic carcinoma 8 | 562
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
pediatric high grade glioma 8 | 1,064
primary pancreatic ductal adenocarcinoma 8 | 1,109
spina bifida 8 | 1,074
Alzheimer's disease 7 | 658
Down syndrome 7 | 499
Schizophrenia 7 | 1,160
acute quadriplegic myopathy 7 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
gastric carcinoma 7 | 807
Autosomal recessive predisposition 6 | 1,442
Bipolar Disorder 6 | 666
Chronic Lymphocytic Leukemia 6 | 262
Chronic graft-versus-host disease 6 | 6
Chronic lymphoid leukemia, disease 6 | 13
Depressive disorder 6 | 409
Diarrhea 6 | 253
Immune system cancer 6 | 140
Lymphoid leukemia 6 | 160
Mantle cell lymphoma 6 | 23
Multiple myeloma 6 | 1,332
Waldenström macroglobulinemia 6 | 6
esophageal adenocarcinoma 6 | 737
mucosa-associated lymphoid tissue lymphoma 6 | 484
Agammaglobulinemia 5 | 34
Amyotrophic lateral sclerosis 5 | 451
Anemia 5 | 365
Duchenne muscular dystrophy 5 | 601
Epilepsy 5 | 792
Failure to gain weight 5 | 365
Melanoma 5 | 711
Pediatric failure to thrive 5 | 365
Polycythemia vera 5 | 27
Splenomegaly 5 | 190
Stomach Neoplasms 5 | 300
Waldenstrons macroglobulinemia 5 | 765
urothelial carcinoma 5 | 318
Arthritis 4 | 290
Arthritis, Rheumatoid 4 | 174
Diabetes Mellitus, Non-Insulin-Dependent 4 | 145
Endometriosis 4 | 540
Hepatomegaly 4 | 285
Mental Depression 4 | 333
Polycystic ovary syndrome 4 | 360
acute myeloid leukemia 4 | 783
nasopharyngeal carcinoma 4 | 1,058

Tissue

Blood and immune system 73 | 16,909
Endocrine System 73 | 18,159
Female tissues 73 | 17,400
Liver and Pancreas 73 | 16,750
Male tissues 73 | 17,142
Skin and soft tissues 73 | 17,230
Digestive Tract 72 | 17,369
Respiratory system 72 | 16,393
Urinary Tract 72 | 16,678
Nervous System 71 | 16,725
Cardiovascular System 69 | 15,192

Target Family

Kinase 34 | 634
Non-IDG 27 | 12,091
Enzyme 7 | 4,145
Ion Channel 3 | 344
GPCR 1 | 408
Transporter 1 | 473

GO Component

extrinsic component of cytopla... 73 | 73
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sorting nexin-5 SNX5 Tbio Non-IDG -1.23706 20.8 141
Tyrosine-protein kinase Fer FER Tchem Kinase -1.86307 55.4 414
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
Sorting nexin-18 SNX18 Tbio Non-IDG -0.76724 7.20 156
Abelson tyrosine-protein kinase 2 ABL2 Tchem Kinase -1.86293 71.2 358
Tyrosine-protein kinase FRK FRK Tchem Kinase -1.68365 49.2 394
Megakaryocyte-associated tyrosine-protein kinase MATK Tbio Kinase -2.98596 792.3 265
Tyrosine-protein kinase TXK TXK Tchem Kinase -2.28365 191.1 194
GRB2-related adapter protein GRAP Tbio Non-IDG -1.51362 31.8 124
FERM, ARHGEF and pleckstrin domain-containing protein 1 FARP1 Tbio Non-IDG -1.56544 38.3 153