Development Level

Tbio 880 | 10,625
Tchem 243 | 1,890
Tdark 134 | 7,003
Tclin 47 | 602

Collection

GPCR: IDG Consortium (Complete/Control) 1 | 26
GPCR: IDG Consortium (Targets) 1 | 127
Kinase: IDG Consortium (Complete/Control) 1 | 37
Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, complete... 34 | 633
enlarged heart 21 | 111
preweaning lethality, incomple... 19 | 260
decreased lean body mass 14 | 195
embryonic lethality prior to t... 12 | 187
abnormal heart morphology 11 | 51
decreased total body fat amoun... 11 | 186
decreased bone mineral content 10 | 157
decreased bone mineral density 9 | 126
decreased circulating insulin ... 9 | 75
abnormal bone structure 8 | 131
decreased body weight 8 | 174
decreased grip strength 8 | 123
increased bone mineral content 8 | 92
increased circulating alkaline... 8 | 119
abnormal embryo size 7 | 112
abnormal retina morphology 7 | 100
abnormal seminal vesicle morph... 7 | 47
increased mean corpuscular vol... 7 | 91
short tibia 7 | 82
abnormal behavior 6 | 226
abnormal lens morphology 6 | 73
decreased body length 6 | 108
decreased circulating glucose ... 6 | 121
embryonic lethality prior to o... 6 | 148
impaired glucose tolerance 6 | 52
increased bone mineral density 6 | 52
increased total body fat amoun... 6 | 57
abnormal kidney morphology 5 | 30
abnormal sleep behavior 5 | 63
decreased circulating triglyce... 5 | 83
decreased monocyte cell number 5 | 28
improved glucose tolerance 5 | 56
increased fasted circulating g... 5 | 68
increased hematocrit 5 | 36
increased startle reflex 5 | 38
abnormal behavioral response t... 4 | 52
abnormal epididymis morphology 4 | 31
cataract 4 | 26
decreased circulating serum al... 4 | 79
decreased fasted circulating g... 4 | 49
decreased heart weight 4 | 44
decreased threshold for audito... 4 | 32
enlarged epididymis 4 | 27
female infertility 4 | 34
hypoactivity 4 | 89
increased circulating HDL chol... 4 | 63
increased circulating sodium l... 4 | 71
increased exploration in new e... 4 | 56
increased hemoglobin content 4 | 45
increased mean corpuscular hem... 4 | 93
increased or absent threshold ... 4 | 128
limb grasping 4 | 35
male infertility 4 | 62
abnormal coat-hair pigmentatio... 3 | 54
abnormal coping response 3 | 12
abnormal lung morphology 3 | 15
abnormal neural tube closure 3 | 37
abnormal neural tube morpholog... 3 | 8
abnormal retinal pigmentation 3 | 61
abnormal testis morphology 3 | 30
decreased B cell number 3 | 30
decreased caudal vertebrae num... 3 | 49
decreased circulating alanine ... 3 | 53
decreased circulating bilirubi... 3 | 14
decreased circulating choleste... 3 | 85
decreased circulating free fat... 3 | 39
decreased circulating sodium l... 3 | 18
decreased lumbar vertebrae num... 3 | 62
decreased mean corpuscular hem... 3 | 19
decreased startle reflex 3 | 48
embryonic growth retardation 3 | 28
hydrops fetalis 3 | 22
impaired righting response 3 | 19
increased grip strength 3 | 83
increased lean body mass 3 | 107
prenatal lethality prior to he... 3 | 64
small testis 3 | 37
straub tail 3 | 26
abnormal body wall morphology 2 | 7
abnormal coat appearance 2 | 25
abnormal cranium morphology 2 | 32
abnormal embryo turning 2 | 15
abnormal tooth morphology 2 | 24
convulsive seizures 2 | 11
decreased circulating calcium ... 2 | 33
decreased circulating chloride... 2 | 32
decreased circulating iron lev... 2 | 25
decreased eosinophil cell numb... 2 | 41
decreased hemoglobin content 2 | 53
decreased mean corpuscular vol... 2 | 50
decreased rib number 2 | 59
enlarged spleen 2 | 26
increased body length 2 | 20
increased circulating bilirubi... 2 | 16
increased circulating choleste... 2 | 53
increased eosinophil cell numb... 2 | 9
increased heart weight 2 | 37
increased sacral vertebrae num... 2 | 62
thrombocytopenia 2 | 46

Disease

psoriasis 605 | 6,685
ovarian cancer 556 | 8,491
osteosarcoma 449 | 7,933
Cancer 422 | 2,346
lung cancer 414 | 4,473
glioblastoma 385 | 5,572
medulloblastoma, large-cell 361 | 6,234
lung carcinoma 330 | 2,844
intraductal papillary-mucinous adenoma (IPMA) 315 | 2,956
lung adenocarcinoma 314 | 2,714
pancreatic cancer 299 | 2,300
ulcerative colitis 299 | 2,087
intraductal papillary-mucinous neoplasm (IPMN) 292 | 3,289
invasive ductal carcinoma 291 | 2,950
non-small cell lung cancer 290 | 2,798
pilocytic astrocytoma 286 | 3,086
interstitial cystitis 285 | 2,299
malignant mesothelioma 285 | 3,163
Breast cancer 284 | 3,098
intraductal papillary-mucinous carcinoma (IPMC) 275 | 2,988
cystic fibrosis 271 | 1,670
atypical teratoid / rhabdoid tumor 253 | 4,369
diabetes mellitus 248 | 1,663
breast carcinoma 200 | 1,614
pediatric high grade glioma 194 | 2,712
pituitary cancer 187 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 180 | 1,795
ductal carcinoma in situ 179 | 1,745
tuberculosis 175 | 1,563
oligodendroglioma 174 | 2,849
posterior fossa group A ependymoma 173 | 1,511
primary pancreatic ductal adenocarcinoma 171 | 1,271
colon cancer 170 | 1,475
subependymal giant cell astrocytoma 166 | 2,287
adult high grade glioma 159 | 2,148
Atopic dermatitis 157 | 944
primitive neuroectodermal tumor 150 | 3,031
cutaneous lupus erythematosus 137 | 1,056
gastric carcinoma 133 | 832
Carcinoma 132 | 2,147
Kidney disease 130 | 397
adrenocortical carcinoma 129 | 1,427
astrocytic glioma 127 | 2,241
ependymoma 127 | 2,514
nasopharyngeal carcinoma 127 | 1,056
sonic hedgehog group medulloblastoma 127 | 1,482
Duchenne muscular dystrophy 120 | 602
group 4 medulloblastoma 119 | 1,875
Obesity 118 | 616
Rheumatoid Arthritis 118 | 1,170
juvenile dermatomyositis 117 | 1,189
Atherosclerosis 114 | 275
esophageal adenocarcinoma 113 | 737
Asthma 110 | 349
active Crohn's disease 107 | 918
astrocytoma 106 | 1,493
group 3 medulloblastoma 105 | 2,254
acute quadriplegic myopathy 100 | 1,157
Coronary artery disease 98 | 240
Pick disease 97 | 1,893
Arthritis 96 | 248
Hypertension 95 | 293
Prostatic Neoplasms 95 | 471
fibroadenoma 92 | 557
Endometriosis 90 | 535
posterior fossa group B ependymoma 90 | 1,530
Alzheimer's disease 89 | 644
mucosa-associated lymphoid tissue lymphoma 88 | 480
autosomal dominant Emery-Dreifuss muscular dystrophy 83 | 499
Vascular disease 82 | 281
Heart disease 81 | 279
Multiple Sclerosis 81 | 498
Lung disease 80 | 136
Mammary Neoplasms 78 | 410
Cerebrovascular disease 75 | 231
Multiple myeloma 75 | 1,327
primary Sjogren syndrome 74 | 788
dermatomyositis 73 | 966
spina bifida 73 | 1,064
Hypersensitivity reaction type II disease 69 | 235
non-small cell lung carcinoma 69 | 413
Liver disease 68 | 219
periodontitis 68 | 269
Down syndrome 67 | 548
atypical teratoid/rhabdoid tumor 67 | 1,095
Anemia 65 | 252
Hypertensive disease 65 | 193
Osteoporosis 65 | 259
aldosterone-producing adenoma 65 | 664
Stomach Neoplasms 61 | 282
medulloblastoma 61 | 1,524
active ulcerative colitis 58 | 477
Inflammatory bowel disease 57 | 142
Pneumonia 57 | 133
interstitial lung disease 56 | 292
non primary Sjogren syndrome sicca 56 | 840
Drug-Induced Liver Injury 55 | 118
limb girdle muscular dystrophy 2A 54 | 156
Inflammation 53 | 109
chronic rhinosinusitis 53 | 512

Tissue

Digestive Tract 1,250 | 18,472
Nervous System 1,246 | 18,560
Female tissues 1,243 | 18,646
Endocrine System 1,238 | 18,511
Urinary Tract 1,233 | 18,443
Skin and soft tissues 1,226 | 18,114
Liver and Pancreas 1,216 | 18,135
Blood and immune system 1,203 | 17,994
Cardiovascular System 1,199 | 17,957
Male tissues 1,190 | 17,968
Respiratory system 1,175 | 17,483

Target Family

Non-IDG 985 | 11,969
Enzyme 285 | 4,146
Kinase 14 | 634
Transcription Factor 7 | 1,400
Epigenetic 4 | 242
Ion Channel 4 | 341
GPCR 3 | 408
Transporter 2 | 473

GO Component

extracellular space 1,304 | 1,304
nucleus 5,106 | 5,106
cytoplasm 4,984 | 4,984
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,264 | 3,264
extracellular exosome 2,757 | 2,757
nucleoplasm 2,716 | 2,716
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 536 | 536
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-9 IL9 Tbio Non-IDG -2.46520 301.6 339
E-selectin SELE Tchem Non-IDG -3.43650 2598.8 820
Angiopoietin-related protein 2 ANGPTL2 Tbio Non-IDG -1.74019 67.9 132
Proto-oncogene Wnt-1 WNT1 Tbio Non-IDG -2.73870 492.7 294
Galectin-3 LGALS3 Tchem Non-IDG -3.33005 2249.5 911
Insulin-like growth factor-binding protein 3 IGFBP3 Tchem Non-IDG -3.34747 2121.3 411
Vascular endothelial growth factor receptor 1 FLT1 Tclin Kinase -3.36387 2061.0 806
CD40 ligand CD40LG Tchem Non-IDG -4.56976 36580.5 1095
Dipeptidyl peptidase 1 CTSC Tchem Enzyme -3.24582 1740.5 143
Serpin A9 SERPINA9 Tbio Non-IDG -1.93591 84.3 121