Development Level

Tbio 1,001 | 11,651
Tdark 167 | 6,593
Tchem 161 | 1,388
Tclin 51 | 612

Collection

Ion Channel: IDG Consortium (T... 2 | 99
GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 42 | 979
preweaning lethality, incomple... 38 | 499
enlarged heart 28 | 210
decreased vertical activity 25 | 208
abnormal heart morphology 21 | 162
embryonic lethality prior to t... 19 | 278
abnormal seminal vesicle morph... 14 | 114
decreased total body fat amoun... 13 | 207
short tibia 12 | 97
decreased bone mineral content 11 | 151
decreased lean body mass 11 | 135
increased total body fat amoun... 11 | 134
abnormal behavior 10 | 298
decreased circulating glucose ... 10 | 126
abnormal embryo size 9 | 220
abnormal kidney morphology 9 | 65
decreased grip strength 9 | 116
embryonic lethality prior to o... 9 | 239
hypoactivity 9 | 132
increased bone mineral content 9 | 108
cataract 8 | 92
decreased bone mineral density 8 | 126
decreased circulating choleste... 8 | 93
decreased fasted circulating g... 8 | 65
small superior vagus ganglion 8 | 74
abnormal eye morphology 7 | 68
decreased body weight 7 | 161
embryonic growth retardation 7 | 106
impaired glucose tolerance 7 | 75
improved glucose tolerance 7 | 79
increased bone mineral density 7 | 72
increased circulating alkaline... 7 | 122
increased fasted circulating g... 7 | 76
increased hematocrit 7 | 46
increased startle reflex 7 | 112
abnormal bone structure 6 | 187
abnormal sleep behavior 6 | 70
decreased circulating insulin ... 6 | 76
decreased neutrophil cell numb... 6 | 42
hydrometra 6 | 53
increased mean corpuscular hem... 6 | 96
increased mean corpuscular vol... 6 | 92
limb grasping 6 | 41
prolonged ST segment 6 | 36
abnormal retina morphology 5 | 71
decreased circulating HDL chol... 5 | 68
decreased circulating aspartat... 5 | 34
decreased circulating serum al... 5 | 82
decreased circulating triglyce... 5 | 79
decreased erythrocyte cell num... 5 | 62
decreased mean corpuscular vol... 5 | 79
hyperactivity 5 | 148
increased heart weight 5 | 62
increased lean body mass 5 | 172
increased leukocyte cell numbe... 5 | 47
male infertility 5 | 123
prenatal lethality prior to he... 5 | 87
prolonged QT interval 5 | 38
abnormal coat-hair pigmentatio... 4 | 64
abnormal cranium morphology 4 | 36
abnormal gait 4 | 69
abnormal lens morphology 4 | 81
abnormal lung morphology 4 | 26
abnormal tail morphology 4 | 25
abnormal testis morphology 4 | 43
cardiovascular system phenotyp... 4 | 36
decreased blood urea nitrogen ... 4 | 51
decreased body length 4 | 101
decreased circulating bilirubi... 4 | 19
decreased eosinophil cell numb... 4 | 24
decreased hematocrit 4 | 46
decreased mean corpuscular hem... 4 | 31
decreased startle reflex 4 | 75
edema 4 | 59
female infertility 4 | 60
impaired righting response 4 | 26
increased blood urea nitrogen ... 4 | 48
increased lymphocyte cell numb... 4 | 32
increased mean corpuscular hem... 4 | 36
increased monocyte cell number 4 | 63
abnormal epididymis morphology 3 | 42
abnormal liver morphology 3 | 17
abnormal neural tube closure 3 | 46
abnormal retinal vasculature m... 3 | 27
abnormal skin morphology 3 | 50
abnormal snout morphology 3 | 23
abnormal tooth morphology 3 | 24
decreased circulating creatini... 3 | 39
decreased circulating free fat... 3 | 31
decreased circulating iron lev... 3 | 32
decreased circulating sodium l... 3 | 22
decreased circulating total pr... 3 | 49
decreased prepulse inhibition 3 | 82
increased body length 3 | 32
increased circulating HDL chol... 3 | 80
increased circulating choleste... 3 | 66
increased circulating sodium l... 3 | 71
increased circulating triglyce... 3 | 42
increased hemoglobin content 3 | 45
increased or absent threshold ... 3 | 101

Disease

Carcinoma 699 | 11,493
psoriasis 625 | 6,694
ovarian cancer 560 | 8,520
osteosarcoma 457 | 7,950
lung cancer 442 | 4,740
Cancer 435 | 2,499
glioblastoma 424 | 5,792
medulloblastoma, large-cell 365 | 6,241
Breast cancer 345 | 3,578
lung carcinoma 337 | 2,843
ependymoma 329 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 325 | 2,955
lung adenocarcinoma 322 | 2,716
malignant mesothelioma 319 | 3,232
pancreatic cancer 318 | 2,398
non-small cell lung cancer 314 | 2,890
atypical teratoid / rhabdoid tumor 304 | 5,112
invasive ductal carcinoma 304 | 2,951
interstitial cystitis 300 | 2,312
Astrocytoma, Pilocytic 299 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 296 | 3,291
adult high grade glioma 290 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 288 | 2,989
cystic fibrosis 276 | 1,696
ulcerative colitis 264 | 1,819
diabetes mellitus 260 | 1,728
group 3 medulloblastoma 218 | 4,104
breast carcinoma 206 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 204 | 1,962
pituitary cancer 201 | 1,972
tuberculosis 193 | 2,010
Autosomal recessive predisposition 190 | 1,442
ductal carcinoma in situ 189 | 1,745
oligodendroglioma 177 | 2,850
subependymal giant cell astrocytoma 175 | 2,287
colon cancer 170 | 1,478
astrocytic glioma 160 | 2,597
Atopic dermatitis 158 | 952
Kidney cancer 155 | 2,613
primary pancreatic ductal adenocarcinoma 155 | 1,109
primitive neuroectodermal tumor 155 | 3,035
Schizophrenia 147 | 1,160
Kidney disease 143 | 430
cutaneous lupus erythematosus 143 | 1,057
adrenocortical carcinoma 138 | 1,428
Liver Cirrhosis, Experimental 137 | 769
nasopharyngeal carcinoma 134 | 1,058
gastric carcinoma 133 | 807
Hypertension 126 | 396
Obesity 122 | 678
Rheumatoid arthritis 122 | 1,191
Duchenne muscular dystrophy 120 | 601
juvenile dermatomyositis 118 | 1,187
Atherosclerosis 116 | 291
esophageal adenocarcinoma 115 | 737
group 4 medulloblastoma 115 | 1,855
Asthma 111 | 385
Coronary artery disease 108 | 268
active Crohn's disease 107 | 922
Arthritis 105 | 290
acute quadriplegic myopathy 100 | 1,158
active ulcerative colitis 99 | 764
Pick disease 92 | 1,894
Prostatic Neoplasms 92 | 495
autosomal dominant Emery-Dreifuss muscular dystrophy 92 | 510
Endometriosis 91 | 540
Vascular disease 91 | 319
fibroadenoma 91 | 559
Multiple Sclerosis 87 | 540
mucosa-associated lymphoid tissue lymphoma 87 | 484
Alzheimer's disease 85 | 658
Bipolar Disorder 85 | 666
Heart disease 84 | 306
Hypertensive disease 84 | 292
Lung disease 82 | 142
Osteoporosis 82 | 363
astrocytoma 82 | 1,146
pediatric high grade glioma 82 | 1,064
Cerebrovascular disease 80 | 238
Anemia 79 | 365
Melanoma 78 | 711
Breast Neoplasms 77 | 445
periodontitis 77 | 293
Mammary Neoplasms 76 | 425
dermatomyositis 76 | 966
spina bifida 74 | 1,074
Liver disease 73 | 237
Hypersensitivity reaction type II disease 72 | 253
Multiple myeloma 70 | 1,332
Depressive disorder 68 | 409
non primary Sjogren syndrome sicca 67 | 891
primary Sjogren syndrome 67 | 735
Chemical and Drug Induced Liver Injury 65 | 195
Pneumonia 65 | 174
Inflammatory bowel disease 64 | 151
Liver Cirrhosis 64 | 181
limb girdle muscular dystrophy 2A 64 | 213
Diarrhea 63 | 253
Down syndrome 61 | 499
aldosterone-producing adenoma 61 | 665

Tissue

Endocrine System 1,238 | 18,159
Digestive Tract 1,224 | 17,369
Female tissues 1,217 | 17,400
Skin and soft tissues 1,195 | 17,230
Blood and immune system 1,172 | 16,909
Male tissues 1,169 | 17,142
Liver and Pancreas 1,168 | 16,750
Urinary Tract 1,151 | 16,678
Respiratory system 1,108 | 16,393
Nervous System 1,099 | 16,725
Cardiovascular System 953 | 15,192

Target Family

Non-IDG 1,061 | 12,091
Enzyme 282 | 4,145
Kinase 15 | 634
Ion Channel 7 | 344
Transcription Factor 7 | 1,400
Epigenetic 3 | 242
GPCR 3 | 408
Transporter 2 | 473

GO Component

extracellular space 1,380 | 1,380
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-9 IL9 Tbio Non-IDG -2.50811 334.4 459
Annexin A13 ANXA13 Tbio Non-IDG -1.19458 15.6 162
Kallikrein-12 KLK12 Tbio Enzyme -0.99694 11.0 111
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
Proprotein convertase subtilisin/kexin type 6 PCSK6 Tchem Enzyme -2.33983 216.4 239
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
C4b-binding protein alpha chain C4BPA Tbio Non-IDG -2.43425 244.7 172
A disintegrin and metalloproteinase with thrombospondin motifs 2 ADAMTS2 Tbio Enzyme -2.51717 1472.5 133
Protein arginine methyltransferase NDUFAF7, mitochondrial NDUFAF7 Tbio Enzyme -0.45102 2.70 64