Development Level

Tbio 1,166 | 11,651
Tdark 393 | 6,593
Tchem 198 | 1,388
Tclin 76 | 612

Collection

RFA-RM-18-021 5 | 328
GPCR: IDG Consortium (Targets) 2 | 126
Kinase: IDG Consortium (Target... 2 | 125
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 54 | 979
preweaning lethality, incomple... 49 | 499
decreased vertical activity 41 | 208
enlarged heart 32 | 210
abnormal heart morphology 24 | 162
abnormal seminal vesicle morph... 22 | 114
decreased total body fat amoun... 18 | 207
abnormal behavior 17 | 298
decreased bone mineral content 16 | 151
embryonic lethality prior to t... 16 | 278
decreased circulating glucose ... 15 | 126
hypoactivity 14 | 132
increased total body fat amoun... 14 | 134
increased lean body mass 13 | 172
short tibia 13 | 97
abnormal embryo size 12 | 220
abnormal kidney morphology 12 | 65
decreased circulating choleste... 12 | 93
abnormal bone structure 10 | 187
cataract 10 | 92
decreased lean body mass 10 | 135
decreased mean corpuscular vol... 10 | 79
improved glucose tolerance 10 | 79
increased bone mineral content 10 | 108
increased circulating alkaline... 10 | 122
prolonged ST segment 10 | 36
abnormal testis morphology 9 | 43
decreased bone mineral density 9 | 126
impaired glucose tolerance 9 | 75
small superior vagus ganglion 9 | 74
decreased circulating HDL chol... 8 | 68
decreased circulating insulin ... 8 | 76
decreased circulating serum al... 8 | 82
decreased fasted circulating g... 8 | 65
decreased grip strength 8 | 116
decreased lymphocyte cell numb... 8 | 83
decreased startle reflex 8 | 75
embryonic growth retardation 8 | 106
increased bone mineral density 8 | 72
increased circulating HDL chol... 8 | 80
increased startle reflex 8 | 112
small testis 8 | 58
decreased circulating triglyce... 7 | 79
embryonic lethality prior to o... 7 | 239
hydrometra 7 | 53
hyperactivity 7 | 148
increased blood urea nitrogen ... 7 | 48
increased circulating choleste... 7 | 66
increased leukocyte cell numbe... 7 | 47
increased monocyte cell number 7 | 63
increased or absent threshold ... 7 | 101
abnormal coat-hair pigmentatio... 6 | 64
abnormal eye morphology 6 | 68
abnormal retina morphology 6 | 71
abnormal sleep behavior 6 | 70
decreased body length 6 | 101
decreased body weight 6 | 161
decreased circulating creatini... 6 | 39
decreased neutrophil cell numb... 6 | 42
decreased prepulse inhibition 6 | 82
increased circulating total pr... 6 | 28
increased heart weight 6 | 62
increased mean corpuscular vol... 6 | 92
increased neutrophil cell numb... 6 | 46
limb grasping 6 | 41
prolonged QT interval 6 | 38
abnormal gait 5 | 69
abnormal lens morphology 5 | 81
abnormal tail morphology 5 | 25
abnormal tooth morphology 5 | 24
decreased blood urea nitrogen ... 5 | 51
decreased circulating total pr... 5 | 49
decreased erythrocyte cell num... 5 | 62
decreased hematocrit 5 | 46
decreased leukocyte cell numbe... 5 | 73
decreased mean corpuscular hem... 5 | 31
edema 5 | 59
enlarged lymph nodes 5 | 37
increased circulating triglyce... 5 | 42
increased fasted circulating g... 5 | 76
increased hemoglobin content 5 | 45
increased lymphocyte cell numb... 5 | 32
increased mean corpuscular hem... 5 | 96
male infertility 5 | 123
persistence of hyaloid vascula... 5 | 33
thrombocytopenia 5 | 56
abnormal retinal vasculature m... 4 | 27
abnormal skin morphology 4 | 50
abnormal vibrissa morphology 4 | 25
decreased circulating alanine ... 4 | 47
decreased circulating amylase ... 4 | 28
decreased circulating bilirubi... 4 | 19
decreased circulating sodium l... 4 | 22
decreased eosinophil cell numb... 4 | 24
decreased hemoglobin content 4 | 68
impaired righting response 4 | 26
increased circulating iron lev... 4 | 30
increased grip strength 4 | 41
increased hematocrit 4 | 46
increased prepulse inhibition 4 | 32

Disease

Carcinoma 875 | 11,493
psoriasis 780 | 6,694
ovarian cancer 699 | 8,520
osteosarcoma 605 | 7,950
lung cancer 540 | 4,740
glioblastoma 534 | 5,792
medulloblastoma, large-cell 472 | 6,241
Cancer 458 | 2,499
atypical teratoid / rhabdoid tumor 411 | 5,112
ependymoma 402 | 4,679
Breast cancer 397 | 3,578
lung adenocarcinoma 390 | 2,716
lung carcinoma 385 | 2,843
non-small cell lung cancer 377 | 2,890
Astrocytoma, Pilocytic 371 | 3,081
malignant mesothelioma 367 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 364 | 3,291
pancreatic cancer 360 | 2,398
invasive ductal carcinoma 356 | 2,951
adult high grade glioma 352 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 351 | 2,955
interstitial cystitis 345 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 328 | 2,989
diabetes mellitus 300 | 1,728
group 3 medulloblastoma 296 | 4,104
cystic fibrosis 291 | 1,696
ulcerative colitis 288 | 1,819
pituitary cancer 258 | 1,972
tuberculosis 257 | 2,010
oligodendroglioma 249 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 236 | 1,962
breast carcinoma 231 | 1,638
Kidney cancer 227 | 2,613
Autosomal recessive predisposition 220 | 1,442
subependymal giant cell astrocytoma 220 | 2,287
ductal carcinoma in situ 214 | 1,745
primitive neuroectodermal tumor 212 | 3,035
astrocytic glioma 199 | 2,597
cutaneous lupus erythematosus 193 | 1,057
colon cancer 185 | 1,478
Atopic dermatitis 174 | 952
Schizophrenia 174 | 1,160
primary pancreatic ductal adenocarcinoma 167 | 1,109
adrenocortical carcinoma 166 | 1,428
Liver Cirrhosis, Experimental 163 | 769
Kidney disease 153 | 430
juvenile dermatomyositis 151 | 1,187
gastric carcinoma 149 | 807
group 4 medulloblastoma 146 | 1,855
Obesity 144 | 678
Hypertension 143 | 396
Duchenne muscular dystrophy 140 | 601
nasopharyngeal carcinoma 136 | 1,058
Atherosclerosis 133 | 291
Rheumatoid arthritis 133 | 1,191
esophageal adenocarcinoma 130 | 737
Pick disease 126 | 1,894
astrocytoma 126 | 1,146
active Crohn's disease 119 | 922
Melanoma 114 | 711
Coronary artery disease 113 | 268
Multiple myeloma 112 | 1,332
acute quadriplegic myopathy 110 | 1,158
fibroadenoma 109 | 559
Arthritis 107 | 290
autosomal dominant Emery-Dreifuss muscular dystrophy 105 | 510
Bipolar Disorder 103 | 666
active ulcerative colitis 103 | 764
pediatric high grade glioma 103 | 1,064
Asthma 102 | 385
Alzheimer's disease 100 | 658
Multiple Sclerosis 100 | 540
dermatomyositis 99 | 966
primary Sjogren syndrome 97 | 735
Vascular disease 96 | 319
Depressive disorder 95 | 409
Prostatic Neoplasms 94 | 495
mucosa-associated lymphoid tissue lymphoma 94 | 484
Osteoporosis 92 | 363
Breast Neoplasms 90 | 445
Cerebrovascular disease 89 | 238
Mammary Neoplasms 89 | 425
Endometriosis 87 | 540
Hypertensive disease 87 | 292
Heart disease 86 | 306
Skin cancer 83 | 469
non primary Sjogren syndrome sicca 82 | 891
Waldenstrons macroglobulinemia 79 | 765
periodontitis 79 | 293
Intellectual disability 78 | 1,016
Liver disease 78 | 237
Lung disease 78 | 142
Anemia 72 | 365
Seizures 72 | 596
Short stature 72 | 531
limb girdle muscular dystrophy 2A 72 | 213
Epilepsy 71 | 792
spina bifida 71 | 1,074
Down syndrome 70 | 499
Hypersensitivity reaction type II disease 70 | 253

Tissue

Endocrine System 1,589 | 18,159
Digestive Tract 1,561 | 17,369
Female tissues 1,550 | 17,400
Skin and soft tissues 1,527 | 17,230
Male tissues 1,519 | 17,142
Blood and immune system 1,494 | 16,909
Liver and Pancreas 1,467 | 16,750
Urinary Tract 1,449 | 16,678
Nervous System 1,399 | 16,725
Respiratory system 1,391 | 16,393
Cardiovascular System 1,222 | 15,192

Target Family

Non-IDG 1,381 | 12,091
Enzyme 394 | 4,145
Kinase 34 | 634
GPCR 9 | 408
Transcription Factor 9 | 1,400
Epigenetic 3 | 242
Ion Channel 2 | 344
Nuclear Receptor 1 | 48

GO Component

extracellular region 1,833 | 1,833
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-9 IL9 Tbio Non-IDG -2.50811 334.4 459
Relaxin-3 RLN3 Tbio Non-IDG -1.88808 92.6 93
Kallikrein-9 KLK9 Tbio Enzyme -0.89030 8.64 143
Kallikrein-12 KLK12 Tbio Enzyme -0.99694 11.0 111
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
Cytoplasmic FMR1-interacting protein 1 CYFIP1 Tbio Non-IDG -1.46134 28.5 64
Neuroendocrine secretory protein 55 GNAS Tbio Non-IDG -2.63356 1389.7 509
Proprotein convertase subtilisin/kexin type 6 PCSK6 Tchem Enzyme -2.33983 216.4 239
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607