Development Level

Tbio 224 | 11,651
Tchem 31 | 1,388
Tdark 10 | 6,593
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 13 | 979
preweaning lethality, incomple... 6 | 499
decreased total body fat amoun... 5 | 207
embryonic lethality prior to t... 5 | 278
abnormal embryo size 4 | 220
decreased body weight 4 | 161
decreased vertical activity 4 | 208
embryonic growth retardation 4 | 106
decreased bone mineral content 3 | 151
decreased lean body mass 3 | 135
decreased neutrophil cell numb... 3 | 42
enlarged heart 3 | 210
increased circulating choleste... 3 | 66
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal coat-hair pigmentatio... 2 | 64
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal sleep behavior 2 | 70
abnormal tooth morphology 2 | 24
decreased body length 2 | 101
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased circulating phosphat... 2 | 27
decreased circulating serum al... 2 | 82
decreased eosinophil cell numb... 2 | 24
decreased erythrocyte cell num... 2 | 62
decreased grip strength 2 | 116
decreased leukocyte cell numbe... 2 | 73
decreased red blood cell distr... 2 | 41
embryonic lethality prior to o... 2 | 239
enlarged lymph nodes 2 | 37
enlarged spleen 2 | 41
impaired righting response 2 | 26
increased body length 2 | 32
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased circulating bilirubi... 2 | 16
increased circulating triglyce... 2 | 42
increased fasted circulating g... 2 | 76
increased heart weight 2 | 62
increased hemoglobin content 2 | 45
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 36
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
pallor 2 | 34
short tibia 2 | 97
abnormal behavioral response t... 1 | 66
abnormal cranium morphology 1 | 36
abnormal esophagus morphology 1 | 5
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal pancreas morphology 1 | 13
abnormal pericardium morpholog... 1 | 26
abnormal skin coloration 1 | 25
abnormal snout morphology 1 | 23
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
abnormal thyroid gland morphol... 1 | 3
abnormal trachea morphology 1 | 3
absent lymph nodes 1 | 3
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
convulsive seizures 1 | 13
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased circulating chloride... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating sodium l... 1 | 22
decreased fasted circulating g... 1 | 65
decreased mean corpuscular hem... 1 | 31
dilated heart left ventricle 1 | 11
edema 1 | 59
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased aggression 1 | 4
increased blood urea nitrogen ... 1 | 48
increased blood uric acid leve... 1 | 5
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased exploration in new e... 1 | 8
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased vertical activity 1 | 24
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
shortened RR interval 1 | 17
thrombocytosis 1 | 27

Disease

Carcinoma 175 | 11,493
ovarian cancer 166 | 8,520
psoriasis 135 | 6,694
glioblastoma 124 | 5,792
osteosarcoma 114 | 7,950
lung cancer 109 | 4,740
pancreatic cancer 103 | 2,398
Breast cancer 102 | 3,578
ependymoma 100 | 4,679
atypical teratoid / rhabdoid tumor 97 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 94 | 2,955
Astrocytoma, Pilocytic 92 | 3,081
medulloblastoma, large-cell 92 | 6,241
lung adenocarcinoma 89 | 2,716
Cancer 88 | 2,499
invasive ductal carcinoma 83 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 82 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 82 | 3,291
malignant mesothelioma 82 | 3,232
lung carcinoma 81 | 2,843
non-small cell lung cancer 74 | 2,890
adult high grade glioma 72 | 3,801
diabetes mellitus 71 | 1,728
ulcerative colitis 69 | 1,819
Duchenne muscular dystrophy 68 | 601
Kidney cancer 68 | 2,613
cystic fibrosis 68 | 1,696
primary pancreatic ductal adenocarcinoma 67 | 1,109
group 3 medulloblastoma 62 | 4,104
breast carcinoma 61 | 1,638
interstitial cystitis 59 | 2,312
gastric carcinoma 56 | 807
ductal carcinoma in situ 54 | 1,745
pituitary cancer 53 | 1,972
juvenile dermatomyositis 51 | 1,187
oligodendroglioma 50 | 2,850
primitive neuroectodermal tumor 49 | 3,035
autosomal dominant Emery-Dreifuss muscular dystrophy 48 | 510
colon cancer 48 | 1,478
subependymal giant cell astrocytoma 48 | 2,287
pancreatic ductal adenocarcinoma liver metastasis 46 | 1,962
Autosomal recessive predisposition 45 | 1,442
Multiple myeloma 43 | 1,332
acute quadriplegic myopathy 43 | 1,158
Liver Cirrhosis, Experimental 42 | 769
nasopharyngeal carcinoma 42 | 1,058
adrenocortical carcinoma 41 | 1,428
Atopic dermatitis 40 | 952
limb girdle muscular dystrophy 2A 37 | 213
astrocytic glioma 33 | 2,597
group 4 medulloblastoma 33 | 1,855
astrocytoma 32 | 1,146
fibroadenoma 32 | 559
Becker muscular dystrophy 31 | 191
Kidney disease 30 | 430
esophageal adenocarcinoma 30 | 737
pediatric high grade glioma 30 | 1,064
Atherosclerosis 29 | 291
Waldenstrons macroglobulinemia 29 | 765
Melanoma 28 | 711
Schizophrenia 28 | 1,160
dermatomyositis 28 | 966
non primary Sjogren syndrome sicca 27 | 891
Liver cancer 26 | 604
Osteoarthritis 26 | 184
interstitial lung disease 25 | 298
tuberculosis 25 | 2,010
Hypertension 24 | 396
Hypertensive disease 24 | 292
Breast Neoplasms 23 | 445
Coronary artery disease 23 | 268
Short stature 23 | 531
Mammary Neoplasms 22 | 425
Myopia 22 | 176
cutaneous lupus erythematosus 22 | 1,057
medulloblastoma 22 | 720
urothelial carcinoma 22 | 318
Degenerative polyarthritis 21 | 115
Prostatic Neoplasms 21 | 495
Skin cancer 21 | 469
sonic hedgehog group medulloblastoma 21 | 467
pterygium 20 | 76
Acquired scoliosis 19 | 281
Curvature of spine 19 | 282
Heart disease 19 | 306
Heart failure 19 | 162
Muscle hypotonia 19 | 571
Obesity 19 | 678
Osteoporosis 19 | 363
Rheumatoid arthritis 19 | 1,191
active Crohn's disease 19 | 922
active ulcerative colitis 19 | 764
Abortion, Spontaneous 18 | 109
Down syndrome 18 | 499
Glaucoma 18 | 239
Spontaneous abortion 18 | 113
mucosa-associated lymphoid tissue lymphoma 18 | 484
Liver Cirrhosis 17 | 181
Vascular disease 17 | 319
Intellectual disability 16 | 1,016

Tissue

Digestive Tract 264 | 17,369
Endocrine System 264 | 18,159
Female tissues 264 | 17,400
Skin and soft tissues 264 | 17,230
Liver and Pancreas 262 | 16,750
Urinary Tract 262 | 16,678
Male tissues 261 | 17,142
Blood and immune system 260 | 16,909
Nervous System 253 | 16,725
Respiratory system 253 | 16,393
Cardiovascular System 248 | 15,192

Target Family

Non-IDG 217 | 12,091
Enzyme 43 | 4,145
Kinase 3 | 634
Transporter 2 | 473
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

GO Component

extracellular matrix 267 | 267
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-complex protein 1 subunit zeta CCT6A Tbio Non-IDG -1.39880 26.2 90
Amelogenin, Y isoform AMELY Tbio Non-IDG -2.86429 712.3 22
Proprotein convertase subtilisin/kexin type 6 PCSK6 Tchem Enzyme -2.33983 216.4 239
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Secreted phosphoprotein 24 SPP2 Tbio Non-IDG -1.20992 21.1 29
Desmoglein-1 DSG1 Tbio Non-IDG -2.72159 516.2 406
EMILIN-1 EMILIN1 Tbio Non-IDG -1.54226 36.3 0
Retinoic acid receptor responder protein 2 RARRES2 Tbio Non-IDG -2.41772 314.1 196
Lysyl oxidase homolog 2 LOXL2 Tbio Enzyme -2.24186 173.0 274
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222