Development Level

Tbio 1,896 | 10,625
Tchem 454 | 1,890
Tdark 290 | 7,003
Tclin 118 | 602

Collection

Eligible Ion Channel Proteins 14 | 117
Eligible Kinase Proteins 7 | 134
Eligible non-olfactory GPCR Proteins 5 | 143

IMPC Term

preweaning lethality, complete... 107 | 633
abnormal behavior 46 | 226
preweaning lethality, incomple... 43 | 260
decreased lean body mass 42 | 195
embryonic lethality prior to t... 39 | 187
decreased total body fat amoun... 36 | 186
embryonic lethality prior to o... 32 | 148
decreased bone mineral content 30 | 157
decreased grip strength 28 | 123
increased circulating alkaline... 28 | 119
increased or absent threshold ... 27 | 128
decreased body weight 25 | 174
enlarged heart 25 | 111
abnormal bone structure 24 | 131
decreased bone mineral density 24 | 126
decreased body length 23 | 108
abnormal embryo size 21 | 112
hyperactivity 21 | 108
hypoactivity 21 | 89
increased mean corpuscular vol... 21 | 91
short tibia 20 | 82
abnormal retina morphology 19 | 100
decreased circulating insulin ... 19 | 75
increased mean corpuscular hem... 19 | 93
abnormal lens morphology 16 | 73
decreased mean corpuscular vol... 16 | 50
impaired glucose tolerance 16 | 52
increased bone mineral content 16 | 92
increased lean body mass 16 | 107
decreased circulating glucose ... 15 | 121
decreased circulating triglyce... 14 | 83
decreased circulating HDL chol... 13 | 77
decreased hemoglobin content 13 | 53
improved glucose tolerance 13 | 56
increased exploration in new e... 13 | 56
increased fasted circulating g... 13 | 68
abnormal bone mineralization 12 | 55
abnormal retinal pigmentation 12 | 61
abnormal seminal vesicle morph... 12 | 47
decreased leukocyte cell numbe... 12 | 54
increased blood urea nitrogen ... 12 | 44
increased grip strength 12 | 83
decreased circulating serum al... 11 | 79
decreased erythrocyte cell num... 11 | 43
decreased startle reflex 11 | 48
decreased circulating choleste... 10 | 85
increased circulating sodium l... 10 | 71
male infertility 10 | 62
prenatal lethality prior to he... 10 | 64
abnormal QRS complex 9 | 25
abnormal heart morphology 9 | 51
abnormal neural tube closure 9 | 37
decreased circulating alkaline... 9 | 41
decreased heart weight 9 | 44
decreased mean corpuscular hem... 9 | 34
decreased threshold for audito... 9 | 32
increased bone mineral density 9 | 52
cardiovascular system phenotyp... 8 | 35
decreased caudal vertebrae num... 8 | 49
decreased eosinophil cell numb... 8 | 41
decreased lumbar vertebrae num... 8 | 62
decreased prepulse inhibition 8 | 52
decreased rib number 8 | 59
enlarged epididymis 8 | 27
increased circulating chloride... 8 | 43
increased hematocrit 8 | 36
increased leukocyte cell numbe... 8 | 37
increased sacral vertebrae num... 8 | 62
small testis 8 | 37
abnormal cranium morphology 7 | 32
abnormal kidney morphology 7 | 30
corneal opacity 7 | 25
decreased circulating alanine ... 7 | 53
decreased circulating total pr... 7 | 41
increased hemoglobin content 7 | 45
increased red blood cell distr... 7 | 21
increased total body fat amoun... 7 | 57
thrombocytopenia 7 | 46
abnormal cornea morphology 6 | 24
abnormal epididymis morphology 6 | 31
abnormal skin morphology 6 | 23
abnormal sleep behavior 6 | 63
abnormal testis morphology 6 | 30
decreased circulating free fat... 6 | 39
decreased circulating fructosa... 6 | 31
decreased circulating glycerol... 6 | 19
decreased fasted circulating g... 6 | 49
decreased neutrophil cell numb... 6 | 37
enlarged lymph nodes 6 | 27
enlarged spleen 6 | 26
immune system phenotype 6 | 17
increased body weight 6 | 42
increased circulating HDL chol... 6 | 63
increased circulating iron lev... 6 | 25
increased heart weight 6 | 37
abnormal coat/hair pigmentatio... 5 | 54
abnormal gait 5 | 51
abnormal lung morphology 5 | 15
increased circulating potassiu... 5 | 31
increased circulating total pr... 5 | 20

Disease

ovarian cancer 1,559 | 8,484
osteosarcoma 1,203 | 7,933
psoriasis 1,189 | 6,685
medulloblastoma, large-cell 956 | 6,234
glioblastoma 948 | 5,572
lung cancer 945 | 4,466
intraductal papillary-mucinous neoplasm (IPMN) 692 | 3,289
atypical teratoid / rhabdoid tumor 674 | 4,369
invasive ductal carcinoma 625 | 2,950
intraductal papillary-mucinous adenoma (IPMA) 619 | 2,956
Breast cancer 615 | 3,094
pancreatic cancer 613 | 2,300
Cancer 611 | 2,346
intraductal papillary-mucinous carcinoma (IPMC) 609 | 2,988
malignant mesothelioma 608 | 3,162
lung adenocarcinoma 602 | 2,713
non-small cell lung cancer 589 | 2,798
lung carcinoma 582 | 2,844
pilocytic astrocytoma 567 | 3,086
interstitial cystitis 480 | 2,299
ulcerative colitis 475 | 2,087
pediatric high grade glioma 468 | 2,712
pancreatic ductal adenocarcinoma liver metastasis 458 | 1,795
oligodendroglioma 453 | 2,849
primitive neuroectodermal tumor 447 | 3,031
subependymal giant cell astrocytoma 431 | 2,287
Multiple myeloma 420 | 1,327
ependymoma 415 | 2,514
diabetes mellitus 404 | 1,663
breast carcinoma 384 | 1,614
ductal carcinoma in situ 381 | 1,745
cystic fibrosis 375 | 1,665
primary pancreatic ductal adenocarcinoma 363 | 1,271
tuberculosis 346 | 1,557
astrocytoma 341 | 1,493
colon cancer 337 | 1,475
Carcinoma 334 | 2,147
pituitary cancer 333 | 1,972
astrocytic glioma 331 | 2,241
Pick disease 324 | 1,893
adult high grade glioma 315 | 2,148
group 3 medulloblastoma 299 | 2,254
group 4 medulloblastoma 294 | 1,875
posterior fossa group A ependymoma 273 | 1,511
acute quadriplegic myopathy 268 | 1,157
juvenile dermatomyositis 267 | 1,189
adrenocortical carcinoma 254 | 1,427
Waldenstrons macroglobulinemia 252 | 765
esophageal adenocarcinoma 247 | 737
sonic hedgehog group medulloblastoma 238 | 1,482
medulloblastoma 237 | 1,524
dermatomyositis 234 | 933
Duchenne muscular dystrophy 232 | 602
nasopharyngeal carcinoma 232 | 1,056
cutaneous lupus erythematosus 224 | 1,056
Rheumatoid Arthritis 219 | 1,160
Atopic dermatitis 214 | 944
gastric carcinoma 212 | 832
spina bifida 192 | 1,064
active Crohn's disease 186 | 918
posterior fossa group B ependymoma 176 | 1,530
atypical teratoid/rhabdoid tumor 172 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 168 | 499
Prostatic Neoplasms 152 | 471
acute myeloid leukemia 150 | 780
non primary Sjogren syndrome sicca 148 | 840
Down syndrome 147 | 548
primary Sjogren syndrome 146 | 789
Kidney disease 137 | 396
Alzheimer's disease 135 | 644
Obesity 134 | 616
fibroadenoma 128 | 557
aldosterone-producing adenoma 127 | 664
mucosa-associated lymphoid tissue lymphoma 126 | 480
IGA Glomerulonephritis 124 | 454
nephrosclerosis 120 | 329
active ulcerative colitis 119 | 477
pancreatic carcinoma 116 | 567
progressive supranuclear palsy 115 | 674
non-small cell lung carcinoma 104 | 413
Endometriosis 101 | 535
Multiple Sclerosis 101 | 498
tuberculosis and treatment for 6 months 96 | 686
Neurodegenerative disease 94 | 383
Becker muscular dystrophy 93 | 187
Hypertension 93 | 287
Mammary Neoplasms 91 | 410
Vascular disease 91 | 281
Atherosclerosis 89 | 275
Intellectual disability 89 | 573
chronic rhinosinusitis 89 | 512
Polycystic Ovary Syndrome 85 | 332
Stomach Neoplasms 84 | 282
hepatocellular carcinoma 84 | 532
Anemia 81 | 252
Coronary artery disease 81 | 240
Liver carcinoma 81 | 217
Osteoporosis 81 | 257
Schizophrenia 81 | 501
periodontitis 77 | 269

Tissue

Digestive Tract 2,713 | 18,473
Female tissues 2,713 | 18,647
Nervous System 2,709 | 18,561
Liver and Pancreas 2,707 | 18,136
Urinary Tract 2,707 | 18,444
Blood and immune system 2,704 | 17,995
Endocrine System 2,703 | 18,512
Cardiovascular System 2,699 | 17,958
Male tissues 2,697 | 17,969
Respiratory system 2,684 | 17,484
Skin and soft tissues 2,673 | 18,115

Target Family

Non-IDG 1,611 | 11,971
Enzyme 899 | 4,146
Kinase 88 | 634
Transporter 77 | 473
Ion Channel 35 | 341
Transcription Factor 19 | 1,400
GPCR 14 | 406
Epigenetic 13 | 242
Nuclear Receptor 1 | 48
oGPCR 1 | 421

GO Component

extracellular exosome 2,758 | 2,758
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Immunoglobulin kappa variable 3-11 IGKV3-11 Tdark Non-IDG 0.00000 0
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160