Development Level

Tbio 114 | 10,625
Tchem 43 | 1,890
Tclin 37 | 602
Tdark 11 | 7,003

Collection

Eligible Ion Channel Proteins 2 | 117
Eligible non-olfactory GPCR Proteins 2 | 143

IMPC Term

preweaning lethality, incomple... 6 | 260
preweaning lethality, complete... 5 | 633
enlarged heart 4 | 111
increased bone mineral content 3 | 92
abnormal epididymis morphology 2 | 31
abnormal heart morphology 2 | 51
abnormal seminal vesicle morph... 2 | 47
absent vibrissae 2 | 14
increased exploration in new e... 2 | 56
abnormal anxiety-related respo... 1 | 1
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal liver morphology 1 | 5
abnormal lung morphology 1 | 15
abnormal pancreas morphology 1 | 6
abnormal pelvic girdle bone mo... 1 | 11
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
abnormal social/conspecific in... 1 | 3
abnormal spleen morphology 1 | 36
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating glycerol... 1 | 19
decreased circulating insulin ... 1 | 75
decreased fasted circulating g... 1 | 49
decreased leukocyte cell numbe... 1 | 54
decreased monocyte cell number 1 | 28
decreased rib number 1 | 59
decreased total body fat amoun... 1 | 186
embryonic lethality prior to t... 1 | 187
enlarged epididymis 1 | 27
enlarged spleen 1 | 26
hyperactivity 1 | 108
increased CD4-positive, alpha ... 1 | 15
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased fasted circulating g... 1 | 68
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased spleen weight 1 | 3
increased vertical activity 1 | 18
limb grasping 1 | 35
small superior vagus ganglion 1 | 20
straub tail 1 | 26
tremors 1 | 34

Disease

psoriasis 107 | 6,685
osteosarcoma 106 | 7,933
Cancer 100 | 2,346
lung carcinoma 80 | 2,844
lung cancer 79 | 4,466
ovarian cancer 77 | 8,484
glioblastoma 73 | 5,572
interstitial cystitis 73 | 2,299
medulloblastoma, large-cell 66 | 6,234
lung adenocarcinoma 63 | 2,713
ulcerative colitis 60 | 2,087
tuberculosis 59 | 1,557
non-small cell lung cancer 57 | 2,798
cutaneous lupus erythematosus 55 | 1,056
invasive ductal carcinoma 54 | 2,950
Rheumatoid Arthritis 51 | 1,160
pilocytic astrocytoma 50 | 3,086
Breast cancer 48 | 3,094
Hypersensitivity reaction type II disease 48 | 235
diabetes mellitus 45 | 1,663
malignant mesothelioma 45 | 3,162
atypical teratoid / rhabdoid tumor 44 | 4,369
Multiple Sclerosis 43 | 498
intraductal papillary-mucinous carcinoma (IPMC) 43 | 2,988
pancreatic cancer 42 | 2,300
intraductal papillary-mucinous neoplasm (IPMN) 40 | 3,289
pediatric high grade glioma 38 | 2,712
cystic fibrosis 37 | 1,665
intraductal papillary-mucinous adenoma (IPMA) 37 | 2,956
primary Sjogren syndrome 35 | 789
Asthma 33 | 349
ductal carcinoma in situ 33 | 1,745
subependymal giant cell astrocytoma 28 | 2,287
Kidney disease 27 | 396
pituitary cancer 27 | 1,972
posterior fossa group A ependymoma 27 | 1,511
Atherosclerosis 26 | 275
Anemia 25 | 252
sarcoidosis 25 | 358
Human immunodeficiency virus infectious disease 24 | 92
group 4 medulloblastoma 24 | 1,875
juvenile dermatomyositis 24 | 1,189
primitive neuroectodermal tumor 24 | 3,031
Allergic hypersensitivity disease 23 | 123
Arthritis 23 | 248
Carcinoma 23 | 2,147
adult high grade glioma 23 | 2,148
Inflammatory bowel disease 22 | 142
Lung disease 22 | 132
primary pancreatic ductal adenocarcinoma 22 | 1,271
Dermatitis 21 | 107
Liver disease 21 | 219
Vascular disease 21 | 281
colon cancer 21 | 1,475
gastric carcinoma 21 | 832
mucosa-associated lymphoid tissue lymphoma 21 | 480
nasopharyngeal carcinoma 21 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,795
Alzheimer's disease 20 | 644
Coronary artery disease 20 | 240
acute quadriplegic myopathy 20 | 1,157
breast carcinoma 20 | 1,614
non-small cell lung carcinoma 20 | 413
Influenza 19 | 142
ependymoma 19 | 2,514
oligodendroglioma 19 | 2,849
periodontitis 19 | 269
adrenocortical carcinoma 18 | 1,427
astrocytoma 18 | 1,493
dermatomyositis 18 | 933
group 3 medulloblastoma 18 | 2,254
sonic hedgehog group medulloblastoma 18 | 1,482
Cerebrovascular disease 17 | 231
Duchenne muscular dystrophy 17 | 602
Hypertension 17 | 287
Multiple myeloma 17 | 1,327
Thrombocytopenia 17 | 105
Acquired immunodeficiency syndrome 16 | 164
Atopic dermatitis 16 | 944
Heart disease 16 | 279
Pneumonia 16 | 133
Tetanus 16 | 66
active Crohn's disease 16 | 918
posterior fossa group B ependymoma 16 | 1,530
Down syndrome 15 | 548
Hypersensitivity 15 | 63
Malaria 15 | 140
Schizophrenia 15 | 501
Vasculitis 15 | 64
autosomal dominant Emery-Dreifuss muscular dystrophy 15 | 499
head and neck cancer and chronic obstructive pulmonary disease 15 | 237
Hepatitis B 14 | 103
Mammary Neoplasms 14 | 410
Obesity 14 | 616
astrocytic glioma 14 | 2,241
pancreatic carcinoma 14 | 567
Eosinophilia 13 | 65
Waldenstrons macroglobulinemia 13 | 765
acute myeloid leukemia 13 | 780
esophageal adenocarcinoma 13 | 737

Tissue

Female tissues 187 | 18,647
Urinary Tract 187 | 18,444
Digestive Tract 186 | 18,473
Nervous System 186 | 18,561
Respiratory system 186 | 17,484
Blood and immune system 185 | 17,995
Cardiovascular System 185 | 17,958
Endocrine System 185 | 18,512
Skin and soft tissues 185 | 18,115
Liver and Pancreas 184 | 18,136
Male tissues 184 | 17,969

Target Family

Non-IDG 159 | 11,971
Enzyme 13 | 4,146
Ion Channel 13 | 341
GPCR 11 | 406
Kinase 5 | 634
Transporter 4 | 473

GO Component

external side of plasma membra... 205 | 205
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Natural killer cell receptor 2B4 CD244 Tbio Non-IDG -2.27438 190.1 418
Solute carrier family 2, facilitated glucose transporter member 4 SLC2A4 Tchem Transporter -3.30074 2066.8 474
Fibrinogen alpha chain FGA Tbio Non-IDG -2.84597 716.2 457
Signal peptide, CUB and EGF-like domain-containing protein 1 SCUBE1 Tbio Non-IDG -1.25952 24.9 65
HLA class II histocompatibility antigen, DRB1-9 beta chain HLA-DRB1 Tbio Non-IDG 0.00000 0
Tumor necrosis factor receptor superfamily member 9 TNFRSF9 Tbio Non-IDG -2.71753 714.2 490
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.27492 2052.7 1794
Interleukin-2 receptor subunit beta IL2RB Tclin Non-IDG -2.08442 120.9 537