Development Level

Tbio 146 | 11,651
Tclin 41 | 612
Tdark 33 | 6,593
Tchem 27 | 1,388

Collection

GPCR: IDG Consortium (Targets) 2 | 126
RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Complete... 1 | 25
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, incomple... 8 | 499
decreased vertical activity 6 | 208
embryonic lethality prior to t... 6 | 278
abnormal seminal vesicle morph... 5 | 114
enlarged heart 5 | 210
preweaning lethality, complete... 5 | 979
embryonic lethality prior to o... 4 | 239
small superior vagus ganglion 4 | 74
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
abnormal heart morphology 3 | 162
decreased heart weight 3 | 27
embryonic growth retardation 3 | 106
increased bone mineral content 3 | 108
abnormal epididymis morphology 2 | 42
abnormal lung morphology 2 | 26
abnormal skin morphology 2 | 50
abnormal spleen morphology 2 | 55
decreased bone mineral content 2 | 151
decreased lymphocyte cell numb... 2 | 83
decreased neutrophil cell numb... 2 | 42
decreased total body fat amoun... 2 | 207
enlarged uterus 2 | 11
hydrometra 2 | 53
increased anti-nuclear antigen... 2 | 19
increased bone mineral density 2 | 72
increased circulating HDL chol... 2 | 80
increased circulating iron lev... 2 | 30
increased circulating triglyce... 2 | 42
increased neutrophil cell numb... 2 | 46
prolonged ST segment 2 | 36
abnormal anxiety-related respo... 1 | 1
abnormal bone structure 1 | 187
abnormal cecum morphology 1 | 7
abnormal colon morphology 1 | 3
abnormal duodenum morphology 1 | 4
abnormal eye anterior chamber ... 1 | 9
abnormal liver morphology 1 | 17
abnormal pancreas morphology 1 | 13
abnormal pelvic girdle bone mo... 1 | 12
abnormal social-conspecific in... 1 | 3
abnormal vertebrae morphology 1 | 18
absent vibrissae 1 | 12
cataract 1 | 92
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating unsatura... 1 | 2
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased monocyte cell number 1 | 8
decreased startle reflex 1 | 75
enlarged cecum 1 | 5
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
female infertility 1 | 60
hyperactivity 1 | 148
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased CD4-positive, alpha ... 1 | 4
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased eosinophil cell numb... 1 | 11
increased erythrocyte cell num... 1 | 39
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased spleen weight 1 | 10
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
male infertility 1 | 123
prolonged PR interval 1 | 15
prolonged QT interval 1 | 38
short tibia 1 | 97
tremors 1 | 39

Disease

Carcinoma 132 | 11,493
osteosarcoma 119 | 7,950
psoriasis 119 | 6,694
Cancer 110 | 2,499
lung cancer 96 | 4,740
lung carcinoma 89 | 2,843
ovarian cancer 89 | 8,520
interstitial cystitis 84 | 2,312
glioblastoma 82 | 5,792
medulloblastoma, large-cell 74 | 6,241
tuberculosis 74 | 2,010
non-small cell lung cancer 71 | 2,890
lung adenocarcinoma 68 | 2,716
ulcerative colitis 68 | 1,819
Breast cancer 66 | 3,578
invasive ductal carcinoma 63 | 2,951
cutaneous lupus erythematosus 58 | 1,057
ependymoma 58 | 4,679
malignant mesothelioma 58 | 3,232
Rheumatoid arthritis 55 | 1,191
atypical teratoid / rhabdoid tumor 55 | 5,112
Astrocytoma, Pilocytic 54 | 3,081
Hypersensitivity reaction type II disease 53 | 253
diabetes mellitus 52 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 50 | 2,989
pancreatic cancer 49 | 2,398
adult high grade glioma 48 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 47 | 3,291
Multiple Sclerosis 46 | 540
intraductal papillary-mucinous adenoma (IPMA) 44 | 2,955
Autosomal recessive predisposition 43 | 1,442
cystic fibrosis 39 | 1,696
Asthma 37 | 385
Schizophrenia 37 | 1,160
ductal carcinoma in situ 35 | 1,745
Liver Cirrhosis, Experimental 34 | 769
primary Sjogren syndrome 34 | 735
Arthritis 33 | 290
Kidney cancer 31 | 2,613
Kidney disease 31 | 430
subependymal giant cell astrocytoma 31 | 2,287
Human immunodeficiency virus infectious disease 30 | 138
pituitary cancer 30 | 1,972
Anemia 29 | 365
sarcoidosis 29 | 370
Atherosclerosis 28 | 291
colon cancer 28 | 1,478
group 3 medulloblastoma 28 | 4,104
group 4 medulloblastoma 28 | 1,855
Vascular disease 27 | 319
juvenile dermatomyositis 26 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 26 | 1,962
periodontitis 26 | 293
primitive neuroectodermal tumor 25 | 3,035
Allergic hypersensitivity disease 24 | 126
Alzheimer's disease 24 | 658
Dermatitis 24 | 157
Inflammatory bowel disease 24 | 151
Pneumonia 24 | 174
mucosa-associated lymphoid tissue lymphoma 24 | 484
primary pancreatic ductal adenocarcinoma 24 | 1,109
Liver disease 23 | 237
Lung disease 23 | 142
Splenomegaly 23 | 190
breast carcinoma 23 | 1,638
nasopharyngeal carcinoma 23 | 1,058
Coronary artery disease 22 | 268
Duchenne muscular dystrophy 22 | 601
acute quadriplegic myopathy 22 | 1,158
adrenocortical carcinoma 22 | 1,428
gastric carcinoma 22 | 807
oligodendroglioma 22 | 2,850
Bipolar Disorder 21 | 666
Hepatomegaly 21 | 285
Influenza 21 | 142
Lymphoproliferative syndrome 21 | 58
Multiple myeloma 21 | 1,332
Diarrhea 20 | 253
Hypertension 20 | 396
astrocytoma 20 | 1,146
head and neck cancer and chronic obstructive pulmonary disease 20 | 239
Arthritis, Rheumatoid 19 | 174
Atopic dermatitis 19 | 952
Malaria 19 | 160
Thrombocytopenia 19 | 197
Vasculitis 19 | 80
astrocytic glioma 19 | 2,597
dermatomyositis 19 | 966
pediatric high grade glioma 19 | 1,064
Melanoma 18 | 711
Cerebrovascular disease 17 | 238
Fever 17 | 138
Heart disease 17 | 306
Hypereosinophilic syndrome 17 | 71
Hypertensive disease 17 | 292
Immunologic Deficiency Syndromes 17 | 113
Tetanus 17 | 68
autosomal dominant Emery-Dreifuss muscular dystrophy 17 | 510
Down syndrome 16 | 499
pancreatic carcinoma 16 | 562

Tissue

Endocrine System 198 | 18,159
Digestive Tract 195 | 17,369
Female tissues 194 | 17,400
Skin and soft tissues 194 | 17,230
Blood and immune system 193 | 16,909
Liver and Pancreas 191 | 16,750
Male tissues 190 | 17,142
Urinary Tract 189 | 16,678
Respiratory system 186 | 16,393
Nervous System 183 | 16,725
Cardiovascular System 173 | 15,192

Target Family

Non-IDG 196 | 12,091
Ion Channel 15 | 344
Enzyme 14 | 4,145
GPCR 11 | 408
Kinase 7 | 634
Transporter 4 | 473

GO Component

external side of plasma membra... 247 | 247
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388
Integrin alpha-2 ITGA2 Tbio Non-IDG -2.58423 335.9 895
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Interleukin-6 receptor subunit beta IL6ST Tclin Non-IDG -1.72489 55.4 555