Development Level

Tbio 160 | 11,445
Tclin 30 | 613
Tchem 27 | 1,598
Tdark 22 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 22 | 979
preweaning lethality, incomple... 8 | 499
abnormal behavior 6 | 298
embryonic lethality prior to t... 6 | 278
abnormal embryo size 5 | 220
decreased circulating insulin ... 4 | 76
enlarged heart 4 | 210
increased circulating alkaline... 4 | 122
increased fasted circulating g... 4 | 76
limb grasping 4 | 41
abnormal bone structure 3 | 187
abnormal seminal vesicle morph... 3 | 114
decreased bone mineral density 3 | 126
decreased circulating alkaline... 3 | 46
decreased fasted circulating g... 3 | 65
decreased grip strength 3 | 116
decreased large unstained cell... 3 | 11
decreased lymphocyte cell numb... 3 | 83
decreased mean corpuscular hem... 3 | 50
decreased prepulse inhibition 3 | 82
decreased total body fat amoun... 3 | 207
embryonic growth retardation 3 | 106
embryonic lethality prior to o... 3 | 239
increased bone mineral content 3 | 108
increased bone mineral density 3 | 72
increased circulating sodium l... 3 | 71
increased heart weight 3 | 62
increased startle reflex 3 | 112
increased total body fat amoun... 3 | 134
abnormal behavioral response t... 2 | 66
abnormal craniofacial morpholo... 2 | 33
abnormal epididymis morphology 2 | 42
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
abnormal neural tube closure 2 | 46
abnormal retina morphology 2 | 71
cataract 2 | 92
decreased body weight 2 | 161
decreased circulating lactate ... 2 | 3
decreased circulating triglyce... 2 | 79
decreased eosinophil cell numb... 2 | 24
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular vol... 2 | 79
decreased vertical activity 2 | 208
edema 2 | 59
enlarged epididymis 2 | 31
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
impaired pupillary reflex 2 | 26
increased circulating HDL chol... 2 | 80
increased circulating glucose ... 2 | 24
increased erythrocyte cell num... 2 | 39
increased heart rate 2 | 23
increased hematocrit 2 | 46
increased lean body mass 2 | 172
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
increased spleen weight 2 | 10
prolonged ST segment 2 | 36
small testis 2 | 58
small thymus 2 | 16
tremors 2 | 39
trunk curl 2 | 16
abnormal body wall morphology 1 | 9
abnormal cornea morphology 1 | 31
abnormal embryo turning 1 | 31
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal neural tube morpholog... 1 | 12
abnormal testis morphology 1 | 43
brachydactyly 1 | 19
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
enlarged spleen 1 | 41
hydrometra 1 | 53
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased circulating alanine ... 1 | 13
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased exploration in new e... 1 | 8
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
prenatal lethality 1 | 28
small spleen 1 | 19
small superior vagus ganglion 1 | 74
stereotypic behavior 1 | 3

Disease

Carcinoma 157 | 11,493
ovarian cancer 138 | 8,520
osteosarcoma 125 | 7,950
glioblastoma 98 | 5,792
psoriasis 96 | 6,694
medulloblastoma, large-cell 91 | 6,241
lung cancer 79 | 4,740
atypical teratoid / rhabdoid tumor 77 | 5,112
ependymoma 69 | 4,679
Breast cancer 59 | 3,578
Cancer 56 | 2,499
adult high grade glioma 54 | 3,801
malignant mesothelioma 54 | 3,232
Astrocytoma, Pilocytic 53 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 53 | 2,955
invasive ductal carcinoma 53 | 2,951
oligodendroglioma 49 | 2,850
intraductal papillary-mucinous neoplasm (IPMN) 46 | 3,291
lung adenocarcinoma 46 | 2,716
group 3 medulloblastoma 45 | 4,104
pancreatic cancer 45 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 44 | 2,989
Kidney cancer 43 | 2,613
non-small cell lung cancer 43 | 2,890
astrocytic glioma 42 | 2,597
primitive neuroectodermal tumor 41 | 3,035
tuberculosis 41 | 2,010
lung carcinoma 40 | 2,843
Pick disease 38 | 1,894
Schizophrenia 37 | 1,160
group 4 medulloblastoma 34 | 1,855
subependymal giant cell astrocytoma 34 | 2,287
diabetes mellitus 33 | 1,728
ulcerative colitis 30 | 1,819
interstitial cystitis 29 | 2,312
Rheumatoid arthritis 28 | 1,191
ductal carcinoma in situ 28 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 28 | 1,962
Multiple myeloma 27 | 1,332
juvenile dermatomyositis 27 | 1,187
Alzheimer's disease 26 | 658
Bipolar Disorder 26 | 666
pituitary cancer 26 | 1,972
breast carcinoma 25 | 1,638
Autosomal recessive predisposition 24 | 1,442
Liver Cirrhosis, Experimental 24 | 769
acute quadriplegic myopathy 23 | 1,158
Intellectual disability 21 | 1,016
cutaneous lupus erythematosus 21 | 1,057
cystic fibrosis 21 | 1,696
pediatric high grade glioma 20 | 1,064
adrenocortical carcinoma 19 | 1,428
astrocytoma 19 | 1,146
dermatomyositis 19 | 966
primary pancreatic ductal adenocarcinoma 19 | 1,109
Down syndrome 18 | 499
Dull intelligence 18 | 645
Low intelligence 18 | 645
Mental Retardation 18 | 645
Mental deficiency 18 | 645
Neurodegenerative disease 18 | 414
Poor school performance 18 | 645
gastric carcinoma 18 | 807
Prostatic Neoplasms 17 | 495
Amyotrophic lateral sclerosis 16 | 451
esophageal adenocarcinoma 16 | 737
spina bifida 15 | 1,074
Kidney disease 14 | 430
colon cancer 14 | 1,478
Duchenne muscular dystrophy 13 | 601
Hypertension 13 | 396
Melanoma 13 | 711
pancreatic carcinoma 13 | 562
primary Sjogren syndrome 13 | 735
Dementia 12 | 175
Depressive disorder 12 | 409
Hypertensive disease 12 | 292
Multiple Sclerosis 12 | 540
Waldenstrons macroglobulinemia 12 | 765
active Crohn's disease 12 | 922
aldosterone-producing adenoma 12 | 665
nasopharyngeal carcinoma 12 | 1,058
non primary Sjogren syndrome sicca 12 | 891
Asthma 11 | 385
Mental Depression 11 | 333
Obesity 11 | 678
Seizures 11 | 596
Short stature 11 | 531
mucosa-associated lymphoid tissue lymphoma 11 | 484
Breast Neoplasms 10 | 445
Colorectal Neoplasms 10 | 243
Epilepsy 10 | 792
Parkinson's disease 10 | 392
Skin cancer 10 | 469
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510
fibroadenoma 10 | 559
posterior fossa group A ependymoma 10 | 468
progressive supranuclear palsy 10 | 676
Cognitive delay 9 | 608
Global developmental delay 9 | 608

Tissue

Digestive Tract 237 | 17,369
Endocrine System 236 | 18,159
Skin and soft tissues 235 | 17,230
Female tissues 233 | 17,400
Male tissues 233 | 17,142
Liver and Pancreas 231 | 16,750
Nervous System 231 | 16,725
Urinary Tract 231 | 16,678
Blood and immune system 229 | 16,909
Respiratory system 228 | 16,393
Cardiovascular System 214 | 15,192

Target Family

Non-IDG 145 | 12,091
Enzyme 42 | 4,145
Kinase 20 | 634
GPCR 18 | 408
Transporter 10 | 473
Ion Channel 4 | 344

GO Component

endosome 239 | 239
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endosomal/lysosomal potassium channel TMEM175 TMEM175 Tbio Non-IDG -0.65375 3.76 42
WASH complex subunit 2C WASHC2C Tbio Non-IDG -0.83634 0.00000 45
Beta-nerve growth factor NGF Tchem Non-IDG -4.01592 10936.7 735
Vascular endothelial growth factor receptor 1 FLT1 Tclin Kinase -3.38913 2189.4 953
MAGE-like protein 2 MAGEL2 Tbio Non-IDG -1.95242 83.8 86
CAP-Gly domain-containing linker protein 1 CLIP1 Tbio Non-IDG -2.54943 343.7 221
V-type proton ATPase 116 kDa subunit a isoform 4 ATP6V0A4 Tbio Enzyme -2.84949 692.2 90
Coiled-coil domain-containing protein 115 CCDC115 Tbio Non-IDG -0.34252 2.11 56
Copine-6 CPNE6 Tbio Non-IDG -0.79740 6.43 129
Lysosomal-associated transmembrane protein 4B LAPTM4B Tbio Non-IDG -1.90763 86.1 91