Development Level

Tbio 131 | 10,625
Tchem 33 | 1,890
Tclin 23 | 602
Tdark 21 | 7,003

Collection

Eligible Kinase Proteins 2 | 134
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 13 | 633
decreased grip strength 5 | 123
decreased bone mineral content 4 | 157
decreased total body fat amoun... 4 | 186
embryonic lethality prior to t... 4 | 187
preweaning lethality, incomple... 4 | 260
abnormal behavior 3 | 226
abnormal sleep behavior 3 | 63
decreased circulating triglyce... 3 | 83
decreased fasted circulating g... 3 | 49
decreased lean body mass 3 | 195
increased circulating alkaline... 3 | 119
increased mean corpuscular hem... 3 | 93
limb grasping 3 | 35
abnormal bone structure 2 | 131
abnormal coping response 2 | 12
abnormal embryo size 2 | 112
abnormal kidney morphology 2 | 30
abnormal lens morphology 2 | 73
decreased NK T cell number 2 | 28
decreased blood urea nitrogen ... 2 | 31
decreased bone mineral density 2 | 126
decreased circulating alkaline... 2 | 41
decreased circulating insulin ... 2 | 75
decreased leukocyte cell numbe... 2 | 54
enlarged heart 2 | 111
impaired glucose tolerance 2 | 52
increased blood urea nitrogen ... 2 | 44
increased bone mineral content 2 | 92
increased fasted circulating g... 2 | 68
increased hematocrit 2 | 36
increased or absent threshold ... 2 | 128
abnormal QRS complex 1 | 25
abnormal behavioral response t... 1 | 52
abnormal body wall morphology 1 | 7
abnormal coat/hair pigmentatio... 1 | 54
abnormal digit morphology 1 | 13
abnormal epididymis morphology 1 | 31
abnormal gait 1 | 51
abnormal hair growth 1 | 8
abnormal heart morphology 1 | 51
abnormal limb bud morphology 1 | 15
abnormal pericardium morpholog... 1 | 11
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
abnormal testis morphology 1 | 30
absent vibrissae 1 | 14
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
decreased NK cell number 1 | 16
decreased body length 1 | 108
decreased brain size 1 | 4
decreased circulating bilirubi... 1 | 14
decreased circulating iron lev... 1 | 25
decreased kidney weight 1 | 7
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
decreased prepulse inhibition 1 | 52
decreased rib number 1 | 59
decreased threshold for audito... 1 | 32
embryonic lethality prior to o... 1 | 148
enlarged heart atrium 1 | 2
enlarged spleen 1 | 26
hypoactivity 1 | 89
impaired righting response 1 | 19
improved glucose tolerance 1 | 56
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
increased erythrocyte cell num... 1 | 26
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular vol... 1 | 91
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
no abnormal phenotype detected 1 | 3
pallor 1 | 13
persistence of hyaloid vascula... 1 | 22
premature death 1 | 5
shortened RR interval 1 | 19
small heart 1 | 8
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 11
small stomach 1 | 3
small thymus 1 | 11
stereotypic behavior 1 | 3
tremors 1 | 34
trunk curl 1 | 15
vertebral transformation 1 | 12

Disease

ovarian cancer 125 | 8,484
osteosarcoma 104 | 7,933
psoriasis 87 | 6,685
medulloblastoma, large-cell 77 | 6,234
glioblastoma 75 | 5,572
lung cancer 65 | 4,466
Cancer 51 | 2,346
atypical teratoid / rhabdoid tumor 51 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 48 | 2,956
pilocytic astrocytoma 46 | 3,086
Breast cancer 45 | 3,094
invasive ductal carcinoma 45 | 2,950
lung adenocarcinoma 44 | 2,713
oligodendroglioma 42 | 2,849
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,289
malignant mesothelioma 41 | 3,162
non-small cell lung cancer 40 | 2,798
lung carcinoma 39 | 2,844
intraductal papillary-mucinous carcinoma (IPMC) 38 | 2,988
pancreatic cancer 38 | 2,300
pediatric high grade glioma 38 | 2,712
subependymal giant cell astrocytoma 33 | 2,287
primitive neuroectodermal tumor 32 | 3,031
Carcinoma 31 | 2,147
Pick disease 31 | 1,893
ependymoma 31 | 2,514
diabetes mellitus 28 | 1,663
ulcerative colitis 27 | 2,087
Alzheimer's disease 26 | 644
astrocytic glioma 26 | 2,241
interstitial cystitis 26 | 2,299
adult high grade glioma 25 | 2,148
primary pancreatic ductal adenocarcinoma 25 | 1,271
tuberculosis 25 | 1,557
astrocytoma 24 | 1,493
ductal carcinoma in situ 24 | 1,745
group 4 medulloblastoma 24 | 1,875
Multiple myeloma 23 | 1,327
posterior fossa group B ependymoma 23 | 1,530
group 3 medulloblastoma 22 | 2,254
pituitary cancer 22 | 1,972
posterior fossa group A ependymoma 22 | 1,511
Rheumatoid Arthritis 21 | 1,160
acute quadriplegic myopathy 21 | 1,157
cystic fibrosis 21 | 1,665
juvenile dermatomyositis 21 | 1,189
sonic hedgehog group medulloblastoma 21 | 1,482
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,795
adrenocortical carcinoma 19 | 1,427
atypical teratoid/rhabdoid tumor 19 | 1,095
Down syndrome 18 | 548
breast carcinoma 18 | 1,614
Prostatic Neoplasms 17 | 471
cutaneous lupus erythematosus 17 | 1,056
gastric carcinoma 17 | 832
Kidney disease 16 | 396
esophageal adenocarcinoma 16 | 737
medulloblastoma 16 | 1,524
dermatomyositis 15 | 933
Neurodegenerative disease 14 | 383
spina bifida 14 | 1,064
colon cancer 13 | 1,475
tuberculosis and treatment for 6 months 13 | 686
Amyotrophic Lateral Sclerosis 12 | 431
mucosa-associated lymphoid tissue lymphoma 12 | 480
nasopharyngeal carcinoma 12 | 1,056
Hypertension 11 | 287
Schizophrenia 11 | 501
aldosterone-producing adenoma 11 | 664
fibroadenoma 11 | 557
Asthma 10 | 349
Colorectal Neoplasms 10 | 217
Duchenne muscular dystrophy 10 | 602
Mammary Neoplasms 10 | 410
Waldenstrons macroglobulinemia 10 | 765
active Crohn's disease 10 | 918
pancreatic carcinoma 10 | 567
primary Sjogren syndrome 10 | 789
progressive supranuclear palsy 10 | 674
Atopic dermatitis 9 | 944
Dementia 9 | 129
Intellectual disability 9 | 573
Stomach Neoplasms 9 | 282
non primary Sjogren syndrome sicca 9 | 840
Atherosclerosis 8 | 275
Endometriosis 8 | 535
Hypertensive disease 8 | 193
Multiple Sclerosis 8 | 498
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 499
chronic lymphosyte leukemia 8 | 232
hereditary spastic paraplegia 8 | 313
sarcoidosis 8 | 358
Craniofacial Abnormalities 7 | 147
Neoplasm Metastasis 7 | 138
Polycystic Ovary Syndrome 7 | 332
Toxic encephalopathy 7 | 131
chronic rhinosinusitis 7 | 512
non-small cell lung carcinoma 7 | 413
Migraine 6 | 79
nephrosclerosis 6 | 329

Tissue

Blood and immune system 207 | 17,995
Digestive Tract 207 | 18,473
Female tissues 207 | 18,647
Liver and Pancreas 207 | 18,136
Nervous System 207 | 18,561
Urinary Tract 207 | 18,444
Endocrine System 206 | 18,512
Male tissues 206 | 17,969
Respiratory system 206 | 17,484
Skin and soft tissues 206 | 18,115
Cardiovascular System 205 | 17,958

Target Family

Non-IDG 126 | 11,971
Enzyme 34 | 4,146
Kinase 17 | 634
GPCR 16 | 406
Transporter 10 | 473
Ion Channel 4 | 341
Transcription Factor 1 | 1,400

GO Component

endosome 208 | 208
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable phospholipid-transporting ATPase IIB ATP9B Tdark Transporter -0.57248 3.74 5
ATP-binding cassette sub-family A member 2 ABCA2 Tbio Transporter -1.41708 32.2 125
Interleukin-15 IL15 Tbio Non-IDG -3.01964 1248.2 612
Cytochrome b-245 light chain CYBA Tbio Non-IDG -2.56294 358.8 154
BET1-like protein BET1L Tbio Non-IDG 0.12 0.65 16
H(+)/Cl(-) exchange transporter 5 CLCN5 Tbio Ion Channel -2.29453 217.9 141
Transmembrane protein 184A TMEM184A Tdark Non-IDG -0.20412 2.16 46
Ras-related protein Rab-43 RAB43 Tbio Enzyme -1.56506 35.9 63
Rab11 family-interacting protein 4 RAB11FIP4 Tbio Non-IDG -0.60511 4.75 34
Toll-like receptor 7 TLR7 Tclin Non-IDG -2.92878 974.2 670