Development Level

Tbio 53 | 11,445
Tdark 9 | 6,588
Tchem 5 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to t... 3 | 278
abnormal embryo size 2 | 220
abnormal kidney morphology 2 | 65
abnormal limb bud morphology 2 | 17
embryonic growth retardation 2 | 106
pale yolk sac 2 | 25
pallor 2 | 34
preweaning lethality, incomple... 2 | 499
small testis 2 | 58
abnormal allantois morphology 1 | 8
abnormal blood vessel morpholo... 1 | 5
abnormal chorioallantoic fusio... 1 | 8
abnormal coat- hair morphology 1 | 19
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal left-right axis patte... 1 | 2
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal optic vesicle formati... 1 | 4
abnormal otic vesicle morpholo... 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal pharyngeal arch morph... 1 | 8
abnormal placenta size 1 | 20
abnormal seminal vesicle morph... 1 | 114
abnormal somite shape 1 | 5
abnormal tail bud morphology 1 | 8
abnormal testis morphology 1 | 43
abnormal urinary bladder morph... 1 | 11
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased circulating chloride... 1 | 30
decreased circulating sodium l... 1 | 22
decreased fasted circulating g... 1 | 65
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
enlarged seminal vesicle 1 | 10
hydroencephaly 1 | 14
increased B cell number 1 | 9
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112

Disease

ovarian cancer 43 | 8,520
osteosarcoma 36 | 7,950
Carcinoma 31 | 11,493
glioblastoma 29 | 5,792
medulloblastoma, large-cell 27 | 6,241
lung cancer 25 | 4,740
psoriasis 23 | 6,694
atypical teratoid / rhabdoid tumor 20 | 5,112
ependymoma 19 | 4,679
invasive ductal carcinoma 18 | 2,951
Multiple myeloma 16 | 1,332
Breast cancer 15 | 3,578
pancreatic cancer 15 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
non-small cell lung cancer 14 | 2,890
tuberculosis 14 | 2,010
Astrocytoma, Pilocytic 13 | 3,081
Cancer 13 | 2,499
group 4 medulloblastoma 13 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
lung adenocarcinoma 13 | 2,716
lung carcinoma 13 | 2,843
malignant mesothelioma 13 | 3,232
Autosomal recessive predisposition 12 | 1,442
adult high grade glioma 11 | 3,801
breast carcinoma 11 | 1,638
cutaneous lupus erythematosus 11 | 1,057
interstitial cystitis 11 | 2,312
astrocytoma 10 | 1,146
diabetes mellitus 10 | 1,728
juvenile dermatomyositis 10 | 1,187
cystic fibrosis 9 | 1,696
oligodendroglioma 9 | 2,850
Rheumatoid arthritis 8 | 1,191
active Crohn's disease 8 | 922
dermatomyositis 8 | 966
spina bifida 8 | 1,074
subependymal giant cell astrocytoma 8 | 2,287
Bipolar Disorder 7 | 666
Endometriosis 7 | 540
Schizophrenia 7 | 1,160
acute quadriplegic myopathy 7 | 1,158
esophageal adenocarcinoma 7 | 737
pancreatic carcinoma 7 | 562
pediatric high grade glioma 7 | 1,064
pituitary cancer 7 | 1,972
primitive neuroectodermal tumor 7 | 3,035
ulcerative colitis 7 | 1,819
Kidney cancer 6 | 2,613
Myocardial Ischemia 6 | 169
active ulcerative colitis 6 | 764
astrocytic glioma 6 | 2,597
group 3 medulloblastoma 6 | 4,104
Anemia 5 | 365
Epilepsy 5 | 792
Pick disease 5 | 1,894
Prostatic Neoplasms 5 | 495
Vascular disease 5 | 319
gastric carcinoma 5 | 807
mucosa-associated lymphoid tissue lymphoma 5 | 484
nephrosclerosis 5 | 333
non primary Sjogren syndrome sicca 5 | 891
primary pancreatic ductal adenocarcinoma 5 | 1,109
Atopic dermatitis 4 | 952
Bronchiectasis 4 | 64
Down syndrome 4 | 499
Intellectual disability 4 | 1,016
Liver Cirrhosis, Experimental 4 | 769
Liver disease 4 | 237
Melanoma 4 | 711
Pulmonary emphysema 4 | 48
Stomach Neoplasms 4 | 300
acute myeloid leukemia 4 | 783
chronic rhinosinusitis 4 | 512
colon cancer 4 | 1,478
ductal carcinoma in situ 4 | 1,745
fibroadenoma 4 | 559
interstitial lung disease 4 | 298
posterior fossa group A ependymoma 4 | 468
primary Sjogren syndrome 4 | 735
Cerebrovascular disease 3 | 238
Chronic otitis media 3 | 52
Duchenne muscular dystrophy 3 | 601
Factor VIII deficiency 3 | 10
Heart disease 3 | 306
Hypersensitivity reaction type II disease 3 | 253
Kidney disease 3 | 430
Nasal Polyps 3 | 10
Osteoporosis 3 | 363
Parkinson's disease 3 | 392
Polycystic ovary syndrome 3 | 360
Seizures 3 | 596
Venous Thrombosis 3 | 47
Warburg micro syndrome 3 | 18
aldosterone-producing adenoma 3 | 665
ear infection chronic 3 | 52
hepatocellular carcinoma 3 | 547
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Digestive Tract 66 | 17,369
Endocrine System 66 | 18,159
Female tissues 66 | 17,400
Nervous System 66 | 16,725
Blood and immune system 65 | 16,909
Male tissues 65 | 17,142
Skin and soft tissues 65 | 17,230
Urinary Tract 65 | 16,678
Liver and Pancreas 64 | 16,750
Respiratory system 64 | 16,393
Cardiovascular System 63 | 15,192

Target Family

Non-IDG 53 | 12,091
Enzyme 11 | 4,145
Ion Channel 2 | 344
Kinase 1 | 634
Transporter 1 | 473

GO Component

endoplasmic reticulum-Golgi in... 68 | 68
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 ERGIC2 Tbio Non-IDG -0.85082 8.58 126
Dipeptidyl peptidase 1 CTSC Tchem Enzyme -3.27566 1855.5 168
Lysosome-associated membrane glycoprotein 5 LAMP5 Tbio Non-IDG -0.81661 7.67 83
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303
Transmembrane emp24 domain-containing protein 5 TMED5 Tbio Non-IDG -0.27107 1.67 29
Transmembrane emp24 domain-containing protein 1 TMED1 Tdark Non-IDG -0.57403 3.74 106
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.74914 5601.8 1083
N-acetyltransferase 8 NAT8 Tbio Enzyme -1.74418 54.5 143
Transmembrane emp24 domain-containing protein 9 TMED9 Tdark Non-IDG -0.03714 0.58 112
Protein CLN8 CLN8 Tbio Non-IDG -1.61744 37.6 96