Development Level

Tbio 214 | 11,445
Tchem 46 | 1,598
Tdark 19 | 6,588
Tclin 12 | 613

IMPC Phenotype

preweaning lethality, complete... 11 | 979
preweaning lethality, incomple... 11 | 499
abnormal seminal vesicle morph... 7 | 114
decreased bone mineral content 6 | 151
decreased total body fat amoun... 6 | 207
enlarged heart 6 | 210
increased total body fat amoun... 6 | 134
abnormal heart morphology 5 | 162
decreased circulating HDL chol... 5 | 68
short tibia 5 | 97
decreased circulating choleste... 4 | 93
embryonic lethality prior to t... 4 | 278
impaired glucose tolerance 4 | 75
increased circulating alkaline... 4 | 122
increased circulating triglyce... 4 | 42
increased startle reflex 4 | 112
abnormal embryo size 3 | 220
abnormal femur morphology 3 | 14
decreased body length 3 | 101
decreased body weight 3 | 161
decreased circulating glucose ... 3 | 126
decreased circulating insulin ... 3 | 76
decreased circulating serum al... 3 | 82
decreased circulating total pr... 3 | 49
decreased grip strength 3 | 116
decreased hemoglobin content 3 | 68
decreased lean body mass 3 | 135
decreased lymphocyte cell numb... 3 | 83
decreased mean corpuscular vol... 3 | 79
decreased vertical activity 3 | 208
embryonic lethality prior to o... 3 | 239
increased blood urea nitrogen ... 3 | 48
increased circulating HDL chol... 3 | 80
increased circulating choleste... 3 | 66
increased mean corpuscular hem... 3 | 36
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal coat-hair pigmentatio... 2 | 64
abnormal cranium morphology 2 | 36
abnormal eye morphology 2 | 68
abnormal humerus morphology 2 | 11
abnormal kidney morphology 2 | 65
abnormal liver morphology 2 | 17
abnormal lung morphology 2 | 26
abnormal radius morphology 2 | 8
abnormal skin morphology 2 | 50
abnormal snout morphology 2 | 23
abnormal testis morphology 2 | 43
abnormal tooth morphology 2 | 24
abnormal ulna morphology 2 | 8
decreased circulating amylase ... 2 | 28
decreased circulating bilirubi... 2 | 19
decreased circulating creatini... 2 | 39
decreased circulating fructosa... 2 | 30
decreased circulating iron lev... 2 | 32
decreased erythrocyte cell num... 2 | 62
decreased hematocrit 2 | 46
decreased mean corpuscular hem... 2 | 50
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
embryonic growth retardation 2 | 106
hypoactivity 2 | 132
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased erythrocyte cell num... 2 | 39
increased fasted circulating g... 2 | 76
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
increased monocyte cell number 2 | 63
increased or absent threshold ... 2 | 101
limb grasping 2 | 41
prolonged PR interval 2 | 15
small superior vagus ganglion 2 | 74
vertebral fusion 2 | 23
abnormal craniofacial morpholo... 1 | 33
abnormal ear morphology 1 | 9
abnormal lens morphology 1 | 81
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating calcium ... 1 | 36
decreased eosinophil cell numb... 1 | 24
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased large unstained cell... 1 | 5
increased red blood cell distr... 1 | 34
persistence of hyaloid vascula... 1 | 33
small testis 1 | 58
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 216 | 11,493
ovarian cancer 177 | 8,520
glioblastoma 138 | 5,792
psoriasis 134 | 6,694
osteosarcoma 132 | 7,950
atypical teratoid / rhabdoid tumor 115 | 5,112
lung cancer 115 | 4,740
medulloblastoma, large-cell 106 | 6,241
ependymoma 97 | 4,679
Astrocytoma, Pilocytic 94 | 3,081
pancreatic cancer 88 | 2,398
Breast cancer 87 | 3,578
malignant mesothelioma 87 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 82 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 80 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 80 | 3,291
invasive ductal carcinoma 79 | 2,951
diabetes mellitus 76 | 1,728
lung adenocarcinoma 75 | 2,716
Cancer 73 | 2,499
adult high grade glioma 73 | 3,801
non-small cell lung cancer 71 | 2,890
lung carcinoma 69 | 2,843
Kidney cancer 66 | 2,613
pancreatic ductal adenocarcinoma liver metastasis 65 | 1,962
cystic fibrosis 62 | 1,696
Autosomal recessive predisposition 60 | 1,442
interstitial cystitis 59 | 2,312
ulcerative colitis 58 | 1,819
pituitary cancer 56 | 1,972
primitive neuroectodermal tumor 55 | 3,035
group 3 medulloblastoma 53 | 4,104
tuberculosis 50 | 2,010
primary pancreatic ductal adenocarcinoma 49 | 1,109
subependymal giant cell astrocytoma 48 | 2,287
breast carcinoma 47 | 1,638
ductal carcinoma in situ 47 | 1,745
juvenile dermatomyositis 47 | 1,187
oligodendroglioma 47 | 2,850
adrenocortical carcinoma 44 | 1,428
Duchenne muscular dystrophy 42 | 601
active Crohn's disease 42 | 922
gastric carcinoma 42 | 807
group 4 medulloblastoma 40 | 1,855
Liver Cirrhosis, Experimental 39 | 769
Kidney disease 38 | 430
nasopharyngeal carcinoma 38 | 1,058
autosomal dominant Emery-Dreifuss muscular dystrophy 36 | 510
pediatric high grade glioma 36 | 1,064
esophageal adenocarcinoma 34 | 737
Atherosclerosis 33 | 291
Obesity 32 | 678
acute quadriplegic myopathy 32 | 1,158
Pick disease 31 | 1,894
astrocytoma 31 | 1,146
astrocytic glioma 30 | 2,597
Rheumatoid arthritis 29 | 1,191
colon cancer 29 | 1,478
Coronary artery disease 28 | 268
Hypertension 28 | 396
Liver disease 28 | 237
interstitial lung disease 28 | 298
Becker muscular dystrophy 26 | 191
Melanoma 26 | 711
Multiple myeloma 26 | 1,332
Prostatic Neoplasms 26 | 495
Schizophrenia 26 | 1,160
Skin cancer 25 | 469
non primary Sjogren syndrome sicca 25 | 891
Short stature 24 | 531
Atopic dermatitis 23 | 952
Alzheimer's disease 22 | 658
Hypertensive disease 22 | 292
Osteoporosis 22 | 363
active ulcerative colitis 22 | 764
cutaneous lupus erythematosus 22 | 1,057
dermatomyositis 22 | 966
fibroadenoma 22 | 559
Liver Cirrhosis 21 | 181
Myopia 21 | 176
Vascular disease 21 | 319
limb girdle muscular dystrophy 2A 21 | 213
medulloblastoma 21 | 720
Heart disease 20 | 306
urothelial carcinoma 20 | 318
Arthritis 19 | 290
Cataract 19 | 297
Cerebrovascular disease 19 | 238
Bipolar Disorder 18 | 666
Cardiovascular system disease 18 | 246
Degenerative polyarthritis 18 | 115
Hypoplastic mandible condyle 18 | 275
Liver cancer 18 | 604
Mandibular hypoplasia 18 | 275
Micrognathism 18 | 275
Seizures 18 | 596
Spontaneous abortion 18 | 113
Acquired scoliosis 17 | 281
Curvature of spine 17 | 282
Down syndrome 17 | 499

Tissue

Endocrine System 286 | 18,159
Female tissues 284 | 17,400
Digestive Tract 282 | 17,369
Male tissues 280 | 17,142
Liver and Pancreas 279 | 16,750
Skin and soft tissues 278 | 17,230
Urinary Tract 277 | 16,678
Blood and immune system 275 | 16,909
Nervous System 273 | 16,725
Respiratory system 266 | 16,393
Cardiovascular System 252 | 15,192

Target Family

Non-IDG 207 | 12,091
Enzyme 82 | 4,145
Kinase 1 | 634
Transporter 1 | 473

GO Component

endoplasmic reticulum lumen 291 | 291
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ceroid-lipofuscinosis neuronal protein 6 CLN6 Tbio Non-IDG -1.87357 0.00000 103
Peptidyl-prolyl cis-trans isomerase FKBP7 FKBP7 Tbio Enzyme -1.41965 24.7 112
Collagen alpha-1(XXIII) chain COL23A1 Tbio Non-IDG -0.49550 1.85 112
A disintegrin and metalloproteinase with thrombospondin motifs 7 ADAMTS7 Tbio Enzyme -1.43732 33.7 98
Arylsulfatase F ARSF Tbio Enzyme -0.44326 2.74 138
Protein Wnt-6 WNT6 Tbio Non-IDG -1.65830 46.6 186
Peptidyl-prolyl cis-trans isomerase FKBP14 FKBP14 Tbio Enzyme -1.72246 54.5 157
Dipeptidyl peptidase 1 CTSC Tchem Enzyme -3.27566 1855.5 168
Anoctamin-8 ANO8 Tbio Non-IDG -0.24444 1.60 13
Collagen alpha-1(XXI) chain COL21A1 Tbio Non-IDG -0.67130 4.90 89