Development Level

Tbio 68 | 11,445
Tdark 32 | 6,588
Tchem 4 | 1,598
Tclin 4 | 613

Collection

Kinase: IDG Consortium (Target... 3 | 125
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 7 | 979
preweaning lethality, incomple... 4 | 499
embryonic lethality prior to o... 3 | 239
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
increased circulating alkaline... 2 | 122
increased circulating phosphat... 2 | 26
increased mean corpuscular hem... 2 | 96
increased red blood cell distr... 2 | 34
increased startle reflex 2 | 112
thrombocytopenia 2 | 56
abnormal QT variability 1 | 10
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart left ventricle ... 1 | 16
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal stomach morphology 1 | 10
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating total pr... 1 | 49
decreased heart rate 1 | 18
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
embryonic growth retardation 1 | 106
enlarged seminal vesicle 1 | 10
enlarged uterus 1 | 11
female infertility 1 | 60
hydrometra 1 | 53
hyperactivity 1 | 148
increased circulating LDL chol... 1 | 13
increased circulating alanine ... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating aspartat... 1 | 15
increased circulating free fat... 1 | 20
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
microphthalmia 1 | 26
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
prolonged RR interval 1 | 8
small adrenal glands 1 | 16
small lymph nodes 1 | 1
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74

Disease

Carcinoma 64 | 11,493
osteosarcoma 50 | 7,950
ovarian cancer 47 | 8,520
medulloblastoma, large-cell 33 | 6,241
psoriasis 32 | 6,694
glioblastoma 30 | 5,792
atypical teratoid / rhabdoid tumor 29 | 5,112
ependymoma 28 | 4,679
lung cancer 25 | 4,740
invasive ductal carcinoma 23 | 2,951
adult high grade glioma 22 | 3,801
oligodendroglioma 22 | 2,850
Breast cancer 21 | 3,578
group 3 medulloblastoma 21 | 4,104
malignant mesothelioma 21 | 3,232
astrocytic glioma 19 | 2,597
primitive neuroectodermal tumor 19 | 3,035
Astrocytoma, Pilocytic 18 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
lung carcinoma 18 | 2,843
non-small cell lung cancer 18 | 2,890
Cancer 17 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
interstitial cystitis 15 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
lung adenocarcinoma 15 | 2,716
Kidney cancer 13 | 2,613
pancreatic cancer 13 | 2,398
subependymal giant cell astrocytoma 13 | 2,287
ductal carcinoma in situ 12 | 1,745
tuberculosis 12 | 2,010
diabetes mellitus 11 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
breast carcinoma 10 | 1,638
group 4 medulloblastoma 9 | 1,855
Obesity 8 | 678
Pick disease 8 | 1,894
colon cancer 8 | 1,478
cystic fibrosis 8 | 1,696
spina bifida 8 | 1,074
Parkinson's disease 7 | 392
Schizophrenia 7 | 1,160
astrocytoma 7 | 1,146
dermatomyositis 7 | 966
mucosa-associated lymphoid tissue lymphoma 7 | 484
Rheumatoid arthritis 6 | 1,191
active Crohn's disease 6 | 922
acute quadriplegic myopathy 6 | 1,158
adrenocortical carcinoma 6 | 1,428
pancreatic carcinoma 6 | 562
ulcerative colitis 6 | 1,819
hepatocellular carcinoma 5 | 547
juvenile dermatomyositis 5 | 1,187
pituitary cancer 5 | 1,972
primary pancreatic ductal adenocarcinoma 5 | 1,109
Alzheimer's disease 4 | 658
Anemia 4 | 365
Autistic Disorder 4 | 364
Hypertension 4 | 396
Osteoarthritis 4 | 184
Vascular disease 4 | 319
cutaneous lupus erythematosus 4 | 1,057
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 807
inflammatory breast cancer 4 | 286
non primary Sjogren syndrome sicca 4 | 891
pediatric high grade glioma 4 | 1,064
sonic hedgehog group medulloblastoma 4 | 467
Acquired immunodeficiency syndrome 3 | 197
Atopic dermatitis 3 | 952
Autosomal recessive predisposition 3 | 1,442
Cognitive delay 3 | 608
Diarrhea 3 | 253
Glaucoma 3 | 239
Global developmental delay 3 | 608
Hyperglycemia 3 | 137
Intellectual disability 3 | 1,016
Liver Cirrhosis, Experimental 3 | 769
Mental Depression 3 | 333
Mental and motor retardation 3 | 608
Mood Disorders 3 | 184
Multiple Sclerosis 3 | 540
Multiple myeloma 3 | 1,332
active ulcerative colitis 3 | 764
acute myeloid leukemia 3 | 783
atypical teratoid/rhabdoid tumor 3 | 357
medulloblastoma 3 | 720
nasopharyngeal carcinoma 3 | 1,058
primary Sjogren syndrome 3 | 735
progressive supranuclear palsy 3 | 676
sarcoidosis 3 | 370
tuberculosis and treatment for 3 months 3 | 179
Attention deficit hyperactivity disorder 2 | 278
Bipolar Disorder 2 | 666
Depressive disorder 2 | 409
Diabetes Mellitus, Type 2 2 | 142
Polycystic ovary syndrome 2 | 360
Type 2 diabetes mellitus 2 | 272
non diabetic and post-ischemic heart failure 2 | 200
urothelial carcinoma 2 | 318

Tissue

Endocrine System 108 | 18,159
Blood and immune system 104 | 16,909
Digestive Tract 101 | 17,369
Female tissues 101 | 17,400
Male tissues 101 | 17,142
Skin and soft tissues 101 | 17,230
Urinary Tract 100 | 16,678
Respiratory system 99 | 16,393
Liver and Pancreas 98 | 16,750
Nervous System 97 | 16,725
Cardiovascular System 96 | 15,192

Target Family

Non-IDG 84 | 12,091
Enzyme 9 | 4,145
Transporter 7 | 473
Kinase 5 | 634
Ion Channel 2 | 344
GPCR 1 | 408

GO Component

endomembrane system 108 | 108
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pannexin-3 PANX3 Tbio Ion Channel -1.66465 45.0 71
Pannexin-2 PANX2 Tbio Ion Channel -1.77864 56.1 126
TBC1 domain family member 13 TBC1D13 Tdark Non-IDG -0.10266 1.34 92
Sugar transporter SWEET1 SLC50A1 Tbio Transporter -2.23661 169.6 56
Rab GTPase-activating protein 1 RABGAP1 Tbio Enzyme -0.72004 3.69 184
TBC1 domain family member 26 TBC1D26 Tdark Non-IDG 0.00000 1.00 47
TBC1 domain family member 3G TBC1D3G Tdark Non-IDG 0.00000 5
TBC1 domain family member 8 TBC1D8 Tdark Non-IDG 0.21 0.48 69
Charged multivesicular body protein 1a CHMP1A Tbio Non-IDG -1.15571 14.9 161
TBC1 domain family member 9B TBC1D9B Tdark Non-IDG 0.66 0.43 29