Development Level

Tchem 5 | 1,598

IMPC Phenotype

short tibia 2 | 97
decreased prepulse inhibition 1 | 82
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
small superior vagus ganglion 1 | 74

Disease

Cancer 5 | 2,499
glioblastoma 5 | 5,792
ovarian cancer 5 | 8,520
Carcinoma 4 | 11,493
Chronic hepatitis C 4 | 12
cutaneous lupus erythematosus 4 | 1,057
diabetes mellitus 4 | 1,728
Arthritis 3 | 290
Duchenne muscular dystrophy 3 | 601
acute quadriplegic myopathy 3 | 1,158
cystic fibrosis 3 | 1,696
gastric carcinoma 3 | 807
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
juvenile dermatomyositis 3 | 1,187
lung carcinoma 3 | 2,843
osteosarcoma 3 | 7,950
pancreatic cancer 3 | 2,398
tuberculosis 3 | 2,010
Alzheimer's disease 2 | 658
Astrocytoma, Pilocytic 2 | 3,081
Breast cancer 2 | 3,578
Fascioliasis 2 | 17
Liver Cirrhosis, Experimental 2 | 769
Neoplasm Invasiveness 2 | 161
Obesity 2 | 678
Osteoporosis 2 | 363
Proteinuria 2 | 144
Pycnodysostosis 2 | 5
Schistosomiasis 2 | 35
Sleeping sickness 2 | 37
Vascular disease 2 | 319
adult high grade glioma 2 | 3,801
dermatomyositis 2 | 966
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
periodontitis 2 | 293
primary Sjogren syndrome 2 | 735
psoriasis 2 | 6,694
subependymal giant cell astrocytoma 2 | 2,287
Abnormal skeletal development 1 | 60
Abnormality of epiphysis morphology 1 | 39
Abnormality of pelvic girdle bone morphology 1 | 37
Barrett's esophagus 1 | 182
Blue sclera 1 | 32
Bone pain 1 | 42
Brachycephaly 1 | 88
Brachydactyly 1 | 156
Broad cranium shape 1 | 88
Carcinoma, Renal Cell 1 | 124
Chagas disease 1 | 39
Dementia 1 | 175
Dental abnormalities 1 | 60
Dental caries 1 | 164
Exophthalmos 1 | 112
Failure of exfoliation of primary tooth 1 | 8
Frequent fractures 1 | 53
Frontal bossing 1 | 157
High forehead 1 | 102
Hyperplasia of nose 1 | 23
Hypertrophy of nose 1 | 23
Hypodontia 1 | 81
Hypoplastic toes 1 | 29
Hypotrophic malar bone 1 | 129
Increased fracture rate 1 | 53
Large nose 1 | 23
Late tooth eruption 1 | 61
Lytic lesion 1 | 32
Malar flattening 1 | 129
Midface retrusion 1 | 105
Muscular Diseases 1 | 27
Myopathy 1 | 185
Necrosis 1 | 53
Osteochondrodysplasias 1 | 72
Osteomyelitis 1 | 42
Osteonecrosis 1 | 27
Osteopetrosis 1 | 43
Prominent back of the head 1 | 21
Prominent eyes 1 | 96
Prominent globes 1 | 96
Prominent occiput 1 | 21
Protruding eyes 1 | 96
Recurrence 1 | 33
Renal Cell Carcinoma 1 | 214
Ridged nails 1 | 14
Root resorption 1 | 22
Severe acute respiratory syndrome 1 | 27
Structure of wormian bone 1 | 24
Tall forehead 1 | 102
Tooth Abnormalities 1 | 69
Trichomoniasis 1 | 10
Varying degree of multiple fractures 1 | 53
Wide skull shape 1 | 88
inflammatory breast cancer 1 | 286
posterior fossa group A ependymoma 1 | 468
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Enzyme 5 | 4,145

GO Component

endolysosome lumen 5 | 5
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cathepsin S CTSS Tchem Enzyme -3.31099 1955.9 291
Cathepsin B CTSB Tchem Enzyme -3.72723 5011.5 448
Legumain LGMN Tchem Enzyme -2.36019 233.2 207
Cathepsin L1 CTSL Tchem Enzyme -3.39489 2387.3 416
Cathepsin K CTSK Tchem Enzyme -2.98138 936.0 404