Development Level

Tbio 174 | 11,445
Tchem 12 | 1,598
Tdark 12 | 6,588
Tclin 5 | 613

IMPC Phenotype

preweaning lethality, complete... 9 | 979
preweaning lethality, incomple... 6 | 499
decreased mean corpuscular hem... 4 | 50
abnormal behavior 3 | 298
decreased bone mineral density 3 | 126
increased fasted circulating g... 3 | 76
abnormal bone structure 2 | 187
abnormal craniofacial morpholo... 2 | 33
abnormal embryo size 2 | 220
abnormal sleep behavior 2 | 70
decreased circulating LDL chol... 2 | 38
decreased circulating glucose ... 2 | 126
decreased circulating serum al... 2 | 82
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular vol... 2 | 79
decreased prepulse inhibition 2 | 82
decreased total body fat amoun... 2 | 207
edema 2 | 59
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
hydrometra 2 | 53
hypoactivity 2 | 132
increased circulating chloride... 2 | 41
increased circulating total pr... 2 | 28
increased heart weight 2 | 62
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
small superior vagus ganglion 2 | 74
abnormal coat-hair pigmentatio... 1 | 64
abnormal esophagus morphology 1 | 5
abnormal facial morphology 1 | 17
abnormal forebrain morphology 1 | 10
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal hindbrain morphology 1 | 10
abnormal iris morphology 1 | 13
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal rib morphology 1 | 10
abnormal skin morphology 1 | 50
abnormal tail morphology 1 | 25
abnormal thoracic cage shape 1 | 3
abnormal thymus morphology 1 | 7
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
cleft palate 1 | 8
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating lactate ... 1 | 3
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
embryonic growth retardation 1 | 106
enlarged gallbladder 1 | 2
enlarged kidney 1 | 14
enlarged spleen 1 | 41
exencephaly 1 | 2
female infertility 1 | 60
hyperactivity 1 | 148
increased caudal vertebrae num... 1 | 7
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating fructosa... 1 | 13
increased circulating insulin ... 1 | 3
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased circulating thyroxin... 1 | 7
increased eosinophil cell numb... 1 | 11
increased erythrocyte cell num... 1 | 39
increased heart rate variabili... 1 | 7
increased hematocrit 1 | 46
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
male infertility 1 | 123
microphthalmia 1 | 26
pallor 1 | 34
prolonged PR interval 1 | 15
small thymus 1 | 16
syndactyly 1 | 23
tremors 1 | 39

Disease

Carcinoma 122 | 11,493
psoriasis 106 | 6,694
Cancer 94 | 2,499
ovarian cancer 78 | 8,520
Ankylosing spondylitis 72 | 140
Behcet's disease 70 | 89
diabetes mellitus 66 | 1,728
osteosarcoma 66 | 7,950
medulloblastoma, large-cell 64 | 6,241
Arthritis 61 | 290
glioblastoma 60 | 5,792
Acquired immunodeficiency syndrome 58 | 197
Hypersensitivity reaction type II disease 58 | 253
Uveitis 57 | 103
Herpes zoster 56 | 68
Juvenile rheumatoid arthritis 56 | 111
Stevens-Johnson syndrome 52 | 92
Human immunodeficiency virus infectious disease 51 | 138
Psoriatic arthritis 49 | 86
dermatomyositis 49 | 966
lung cancer 44 | 4,740
Rheumatoid arthritis 43 | 1,191
atypical teratoid / rhabdoid tumor 43 | 5,112
tuberculosis 42 | 2,010
Dermatitis 37 | 157
Astrocytoma, Pilocytic 35 | 3,081
Behcet's syndrome 35 | 50
Congenital adrenal hyperplasia 35 | 73
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Synovitis 35 | 78
Takayasu's arteritis 35 | 53
drug-induced hepatitis 35 | 44
ependymoma 34 | 4,679
invasive ductal carcinoma 29 | 2,951
adult high grade glioma 28 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,955
Kidney cancer 27 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,291
non-small cell lung cancer 27 | 2,890
subependymal giant cell astrocytoma 27 | 2,287
group 3 medulloblastoma 26 | 4,104
Breast cancer 25 | 3,578
malignant mesothelioma 25 | 3,232
oligodendroglioma 25 | 2,850
Liver disease 24 | 237
Multiple Sclerosis 24 | 540
Anemia 23 | 365
Hemochromatosis 23 | 54
Kidney disease 23 | 430
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
pancreatic cancer 23 | 2,398
Hepatitis B 22 | 108
Leprosy 22 | 73
lung carcinoma 22 | 2,843
Birdshot chorioretinopathy 21 | 23
Primary immunodeficiency disease 21 | 54
Skin disease 21 | 66
Pick disease 20 | 1,894
astrocytic glioma 20 | 2,597
breast carcinoma 20 | 1,638
interstitial cystitis 20 | 2,312
primitive neuroectodermal tumor 19 | 3,035
ulcerative colitis 19 | 1,819
juvenile dermatomyositis 18 | 1,187
lung adenocarcinoma 18 | 2,716
astrocytoma 17 | 1,146
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
pituitary cancer 17 | 1,972
Multiple myeloma 16 | 1,332
Schizophrenia 16 | 1,160
ductal carcinoma in situ 16 | 1,745
pediatric high grade glioma 16 | 1,064
Pre-Eclampsia 15 | 68
group 4 medulloblastoma 15 | 1,855
Human immunodeficiency virus type 1, susceptibility to 14 | 26
Psoriasis susceptibility 1 14 | 14
cutaneous lupus erythematosus 14 | 1,057
cystic fibrosis 13 | 1,696
primary Sjogren syndrome 12 | 735
Liver Cirrhosis, Experimental 11 | 769
adrenocortical carcinoma 11 | 1,428
esophageal adenocarcinoma 11 | 737
gastric carcinoma 10 | 807
primary pancreatic ductal adenocarcinoma 10 | 1,109
Alzheimer's disease 9 | 658
Autosomal recessive predisposition 9 | 1,442
Duchenne muscular dystrophy 9 | 601
Intellectual disability 9 | 1,016
aldosterone-producing adenoma 9 | 665
mucosa-associated lymphoid tissue lymphoma 9 | 484
posterior fossa group A ependymoma 9 | 468
spina bifida 9 | 1,074
Waldenstrons macroglobulinemia 8 | 765
active Crohn's disease 8 | 922
fibroadenoma 8 | 559
Prostatic Neoplasms 7 | 495
colon cancer 7 | 1,478
nasopharyngeal carcinoma 7 | 1,058

Tissue

Digestive Tract 130 | 17,369
Endocrine System 129 | 18,159
Female tissues 129 | 17,400
Skin and soft tissues 129 | 17,230
Male tissues 128 | 17,142
Nervous System 128 | 16,725
Liver and Pancreas 126 | 16,750
Respiratory system 126 | 16,393
Blood and immune system 125 | 16,909
Urinary Tract 124 | 16,678
Cardiovascular System 120 | 15,192

Target Family

Non-IDG 163 | 12,091
Enzyme 23 | 4,145
Kinase 7 | 634
Ion Channel 6 | 344
Transporter 3 | 473
GPCR 1 | 408

GO Component

early endosome membrane 203 | 203
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Sorting nexin-13 SNX13 Tbio Non-IDG -0.67169 5.24 65
Sorting nexin-5 SNX5 Tbio Non-IDG -1.23706 20.8 141
TIR domain-containing adapter molecule 2 TICAM2 Tbio Non-IDG -1.18212 14.6 258
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Rab15 effector protein REP15 Tbio Non-IDG -0.44863 2.71 21
Endophilin-A2 SH3GL1 Tbio Non-IDG -2.15479 134.2 257
Lysosome-associated membrane glycoprotein 5 LAMP5 Tbio Non-IDG -0.81661 7.67 83
WD repeat-containing protein 91 WDR91 Tbio Non-IDG -0.72903 5.46 54
Lateral signaling target protein 2 homolog ZFYVE28 Tbio Non-IDG 0.04 0.75 77