Development Level

Tbio 163 | 11,445
Tchem 32 | 1,598
Tdark 26 | 6,588
Tclin 13 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 18 | 979
preweaning lethality, incomple... 8 | 499
abnormal embryo size 5 | 220
decreased body weight 5 | 161
increased circulating alkaline... 5 | 122
increased circulating choleste... 5 | 66
decreased prepulse inhibition 4 | 82
enlarged heart 4 | 210
abnormal bone structure 3 | 187
abnormal craniofacial morpholo... 3 | 33
abnormal kidney morphology 3 | 65
abnormal seminal vesicle morph... 3 | 114
abnormal sleep behavior 3 | 70
decreased circulating HDL chol... 3 | 68
decreased circulating choleste... 3 | 93
decreased circulating glucose ... 3 | 126
decreased circulating serum al... 3 | 82
decreased grip strength 3 | 116
decreased mean corpuscular hem... 3 | 50
edema 3 | 59
embryonic lethality prior to t... 3 | 278
hypoactivity 3 | 132
increased circulating HDL chol... 3 | 80
increased circulating serum al... 3 | 22
increased circulating total pr... 3 | 28
increased fasted circulating g... 3 | 76
increased mean corpuscular vol... 3 | 92
increased total body fat amoun... 3 | 134
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal hindbrain morphology 2 | 10
abnormal midbrain morphology 2 | 10
abnormal neural tube closure 2 | 46
abnormal retina morphology 2 | 71
cataract 2 | 92
decreased blood urea nitrogen ... 2 | 51
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating aspartat... 2 | 34
decreased circulating creatini... 2 | 39
decreased circulating lactate ... 2 | 3
decreased circulating triglyce... 2 | 79
decreased lymphocyte cell numb... 2 | 83
decreased total retina thickne... 2 | 17
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
hydrometra 2 | 53
improved glucose tolerance 2 | 79
increased circulating LDL chol... 2 | 13
increased circulating free fat... 2 | 20
increased erythrocyte cell num... 2 | 39
increased heart weight 2 | 62
increased leukocyte cell numbe... 2 | 47
increased neutrophil cell numb... 2 | 46
increased startle reflex 2 | 112
pallor 2 | 34
short tibia 2 | 97
abnormal body wall morphology 1 | 9
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal motor capabilities-co... 1 | 5
abnormal pericardium morpholog... 1 | 26
abnormal snout morphology 1 | 23
abnormal tooth morphology 1 | 24
decreased IgE level 1 | 6
decreased T cell number 1 | 15
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased mean corpuscular hem... 1 | 31
decreased mean platelet volume 1 | 25
enlarged spleen 1 | 41
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
limb grasping 1 | 41
microphthalmia 1 | 26
premature death 1 | 5
small superior vagus ganglion 1 | 74
small thymus 1 | 16
syndactyly 1 | 23
thrombocytosis 1 | 27
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 148 | 11,493
ovarian cancer 137 | 8,520
osteosarcoma 113 | 7,950
psoriasis 103 | 6,694
glioblastoma 86 | 5,792
medulloblastoma, large-cell 86 | 6,241
lung cancer 67 | 4,740
atypical teratoid / rhabdoid tumor 66 | 5,112
ependymoma 60 | 4,679
Breast cancer 53 | 3,578
Cancer 51 | 2,499
malignant mesothelioma 51 | 3,232
invasive ductal carcinoma 50 | 2,951
adult high grade glioma 47 | 3,801
Kidney cancer 46 | 2,613
lung carcinoma 45 | 2,843
Astrocytoma, Pilocytic 43 | 3,081
diabetes mellitus 41 | 1,728
group 3 medulloblastoma 41 | 4,104
non-small cell lung cancer 41 | 2,890
lung adenocarcinoma 40 | 2,716
oligodendroglioma 40 | 2,850
intraductal papillary-mucinous carcinoma (IPMC) 38 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 38 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 37 | 2,955
subependymal giant cell astrocytoma 37 | 2,287
primitive neuroectodermal tumor 36 | 3,035
astrocytic glioma 32 | 2,597
pancreatic cancer 32 | 2,398
juvenile dermatomyositis 31 | 1,187
interstitial cystitis 30 | 2,312
ulcerative colitis 30 | 1,819
Multiple myeloma 29 | 1,332
Pick disease 29 | 1,894
breast carcinoma 28 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 28 | 1,962
pituitary cancer 28 | 1,972
Autosomal recessive predisposition 27 | 1,442
tuberculosis 27 | 2,010
ductal carcinoma in situ 26 | 1,745
astrocytoma 25 | 1,146
cystic fibrosis 25 | 1,696
Atherosclerosis 23 | 291
Schizophrenia 23 | 1,160
group 4 medulloblastoma 22 | 1,855
Obesity 21 | 678
Alzheimer's disease 20 | 658
Rheumatoid arthritis 20 | 1,191
dermatomyositis 19 | 966
Intellectual disability 18 | 1,016
Neurodegenerative disease 18 | 414
primary pancreatic ductal adenocarcinoma 18 | 1,109
Coronary artery disease 17 | 268
Epilepsy 17 | 792
adrenocortical carcinoma 17 | 1,428
esophageal adenocarcinoma 17 | 737
gastric carcinoma 17 | 807
Bipolar Disorder 16 | 666
Liver Cirrhosis, Experimental 16 | 769
colon cancer 16 | 1,478
Cognitive delay 15 | 608
Dull intelligence 15 | 645
Global developmental delay 15 | 608
Hypertension 15 | 396
Low intelligence 15 | 645
Mental Retardation 15 | 645
Mental and motor retardation 15 | 608
Mental deficiency 15 | 645
Poor school performance 15 | 645
acute quadriplegic myopathy 15 | 1,158
aldosterone-producing adenoma 15 | 665
cutaneous lupus erythematosus 15 | 1,057
nasopharyngeal carcinoma 15 | 1,058
Kidney disease 14 | 430
Melanoma 14 | 711
Seizures 14 | 596
hereditary spastic paraplegia 14 | 318
primary Sjogren syndrome 14 | 735
Cerebrovascular disease 13 | 238
Duchenne muscular dystrophy 13 | 601
Heart disease 13 | 306
Parkinson's disease 13 | 392
active Crohn's disease 13 | 922
pediatric high grade glioma 13 | 1,064
Hypertensive disease 12 | 292
Multiple Sclerosis 12 | 540
Skin cancer 12 | 469
hepatocellular carcinoma 12 | 547
Autistic Disorder 11 | 364
Down syndrome 11 | 499
Lipid metabolism disorder 11 | 114
Liver cancer 11 | 604
Stomach Neoplasms 11 | 300
Waldenstrons macroglobulinemia 11 | 765
acute myeloid leukemia 11 | 783
spina bifida 11 | 1,074
Atopic dermatitis 10 | 952
non primary Sjogren syndrome sicca 10 | 891
pancreatic carcinoma 10 | 562
Short stature 9 | 531

Tissue

Digestive Tract 227 | 17,369
Endocrine System 226 | 18,159
Blood and immune system 225 | 16,909
Male tissues 225 | 17,142
Liver and Pancreas 224 | 16,750
Urinary Tract 224 | 16,678
Female tissues 223 | 17,400
Skin and soft tissues 223 | 17,230
Nervous System 221 | 16,725
Respiratory system 219 | 16,393
Cardiovascular System 214 | 15,192

Target Family

Non-IDG 151 | 12,091
Enzyme 47 | 4,145
Kinase 13 | 634
GPCR 12 | 408
Transporter 6 | 473
Ion Channel 4 | 344
Transcription Factor 1 | 1,400

GO Component

early endosome 234 | 234
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
WASH complex subunit 2C WASHC2C Tbio Non-IDG -0.83634 0.00000 45
Rab11 family-interacting protein 5 RAB11FIP5 Tbio Non-IDG -1.52843 34.5 62
Proteinase-activated receptor 1 F2R Tclin GPCR -2.78393 551.0 453
Sorting nexin-12 SNX12 Tbio Non-IDG -0.39959 3.14 151
WASH complex subunit 5 WASHC5 Tbio Non-IDG -1.43182 26.4 38
MAGE-like protein 2 MAGEL2 Tbio Non-IDG -1.95242 83.8 86
Lysosomal-associated transmembrane protein 4B LAPTM4B Tbio Non-IDG -1.90763 86.1 91
Ankyrin repeat domain-containing protein 27 ANKRD27 Tbio Non-IDG -1.12548 14.6 65
Tumor susceptibility gene 101 protein TSG101 Tbio Non-IDG -2.47780 298.9 332
Charged multivesicular body protein 1a CHMP1A Tbio Non-IDG -1.15571 14.9 161