Development Level

Tbio 11 | 11,445

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal cornea morphology 1 | 31
abnormal joint morphology 1 | 23
abnormal seminal vesicle morph... 1 | 114
brachydactyly 1 | 19
decreased bone mineral content 1 | 151
decreased circulating calcium ... 1 | 36
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
increased erythrocyte cell num... 1 | 39
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134
syndactyly 1 | 23

Disease

Astrocytoma, Pilocytic 10 | 3,081
ependymoma 9 | 4,679
glioblastoma 9 | 5,792
adult high grade glioma 8 | 3,801
atypical teratoid / rhabdoid tumor 8 | 5,112
medulloblastoma, large-cell 8 | 6,241
oligodendroglioma 8 | 2,850
ovarian cancer 8 | 8,520
Carcinoma 7 | 11,493
primitive neuroectodermal tumor 7 | 3,035
astrocytic glioma 6 | 2,597
group 3 medulloblastoma 6 | 4,104
osteosarcoma 6 | 7,950
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
invasive ductal carcinoma 5 | 2,951
Pick disease 4 | 1,894
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung carcinoma 4 | 2,843
psoriasis 4 | 6,694
Bipolar Disorder 3 | 666
Breast cancer 3 | 3,578
Neurodegenerative disease 3 | 414
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
non-small cell lung cancer 3 | 2,890
pituitary cancer 3 | 1,972
subependymal giant cell astrocytoma 3 | 2,287
Anxiety 2 | 136
Anxiety disease 2 | 113
Attention deficit hyperactivity disorder 2 | 278
Autosomal recessive predisposition 2 | 1,442
Depressive disorder 2 | 409
Epilepsy 2 | 792
Fatigue 2 | 182
Huntington's disease 2 | 76
Mental Depression 2 | 333
Mood Disorders 2 | 184
Mood swings 2 | 77
Multiple myeloma 2 | 1,332
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Parkinson's disease 2 | 392
Schizophrenia 2 | 1,160
Skeletal muscle atrophy 2 | 139
Type 2 diabetes mellitus 2 | 272
acute myeloid leukemia 2 | 783
adrenocortical carcinoma 2 | 1,428
breast carcinoma 2 | 1,638
group 4 medulloblastoma 2 | 1,855
malignant mesothelioma 2 | 3,232
muscle degeneration 2 | 139
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
Abnormality of vision 1 | 40
Acanthocytosis 1 | 7
Alcohol dependence 1 | 107
Caudate atrophy 1 | 3
Chorea Acanthocytosis Syndrome 1 | 2
Choreoacanthocytosis 1 | 1
Death in early adulthood 1 | 24
Deglutition Disorders 1 | 132
Diabetes Mellitus, Experimental 1 | 108
Difficulty in tongue movements 1 | 2
Distal upper limb muscle weakness 1 | 2
Drooling 1 | 27
Dysgraphia 1 | 20
Fatty Liver 1 | 70
Forgetful 1 | 40
Glioma 1 | 74
Hearing Loss 1 | 17
Hypobetalipoproteinemia 1 | 3
Hypokinesia of the tongue 1 | 2
Hypomyelinating leukodystrophy 2 1 | 3
Kidney Calculi 1 | 7
Lambert-Eaton myasthenic syndrome 1 | 12
Memory Loss 1 | 40
Memory impairment 1 | 40
Muscle fiber atrophy 1 | 3
Muscle weakness of limb 1 | 21
Neuroacanthocytosis 1 | 6
Neurodegeneration with brain iron accumulation 6 1 | 8
Ovarian Neoplasms 1 | 102
Pantothenate kinase-associated neurodegeneration 1 | 12
Paralysed 1 | 42
Parkinsonian Disorders 1 | 56
Peripheral Neuropathy 1 | 134
Progressive choreoathetosis 1 | 1
Progressive distal muscular atrophy 1 | 2
Protrusion of tongue 1 | 11
Self-mutilation of tongue and lips due to involuntary movements 1 | 1
Sensory neuropathy 1 | 20
Sialorrhea 1 | 28
Social disinhibition 1 | 14
Urine color abnormal 1 | 6
chorea-acanthocytosis 1 | 12
lingual-facial-buccal dyskinesia 1 | 13
ovarian neoplasm 1 | 99
recurrent muscle twitches (symptom) 1 | 1

Tissue

Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Blood and immune system 10 | 16,909
Male tissues 10 | 17,142
Cardiovascular System 9 | 15,192

Target Family

Non-IDG 10 | 12,091
Enzyme 1 | 4,145

GO Component

dense core granule 11 | 11
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Spexin SPX Tbio Non-IDG -2.81062 637.9 19
Vacuolar protein sorting-associated protein 13A VPS13A Tbio Non-IDG -2.19966 172.3 22
Synaptotagmin-7 SYT7 Tbio Non-IDG -1.75931 60.3 170
Augurin C2orf40 Tbio Non-IDG -1.65266 52.0 120
Rab effector MyRIP MYRIP Tbio Non-IDG -1.04097 13.1 128
Corticotropin-releasing factor-binding protein CRHBP Tbio Non-IDG -2.01819 109.0 129
Neuronal calcium sensor 1 NCS1 Tbio Non-IDG -2.39386 263.2 273
Superoxide dismutase [Cu-Zn] SOD1 Tbio Enzyme -3.30643 1972.1 1103
Synaptotagmin-9 SYT9 Tbio Non-IDG -1.01494 10.0 123
Synaptotagmin-5 SYT5 Tbio Non-IDG -0.88138 6.66 127