Development Level

Tbio 76 | 11,445
Tchem 26 | 1,598
Tclin 12 | 613
Tdark 4 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

abnormal behavior 6 | 298
preweaning lethality, complete... 6 | 979
decreased total body fat amoun... 5 | 207
preweaning lethality, incomple... 5 | 499
abnormal bone structure 4 | 187
decreased circulating serum al... 3 | 82
embryonic lethality prior to t... 3 | 278
increased bone mineral content 3 | 108
increased circulating choleste... 3 | 66
abnormal retina morphology 2 | 71
abnormal sleep behavior 2 | 70
decreased body weight 2 | 161
decreased vertical activity 2 | 208
hyperactivity 2 | 148
hypoactivity 2 | 132
increased circulating alkaline... 2 | 122
increased circulating chloride... 2 | 41
increased circulating sodium l... 2 | 71
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
thrombocytopenia 2 | 56
abnormal behavioral response t... 1 | 66
abnormal clavicle morphology 1 | 6
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal iris pigmentation 1 | 4
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased IgG1 level 1 | 8
decreased IgG2b level 1 | 4
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased cardiac output 1 | 3
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating magnesiu... 1 | 13
decreased circulating phosphat... 1 | 27
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased granulocyte number 1 | 6
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased prepulse inhibition 1 | 82
decreased pulmonary respirator... 1 | 5
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged kidney 1 | 14
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased coping response 1 | 4
increased exploration in new e... 1 | 8
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased vertical activity 1 | 24
microphthalmia 1 | 26
premature death 1 | 5
prenatal lethality 1 | 28
short tibia 1 | 97
small superior vagus ganglion 1 | 74
thin ventricular wall 1 | 24
tremors 1 | 39

Disease

Carcinoma 92 | 11,493
medulloblastoma, large-cell 74 | 6,241
glioblastoma 73 | 5,792
ovarian cancer 66 | 8,520
atypical teratoid / rhabdoid tumor 64 | 5,112
ependymoma 63 | 4,679
osteosarcoma 55 | 7,950
adult high grade glioma 52 | 3,801
psoriasis 49 | 6,694
group 3 medulloblastoma 48 | 4,104
Astrocytoma, Pilocytic 44 | 3,081
lung cancer 43 | 4,740
oligodendroglioma 43 | 2,850
primitive neuroectodermal tumor 43 | 3,035
Schizophrenia 38 | 1,160
Kidney cancer 36 | 2,613
lung carcinoma 36 | 2,843
astrocytic glioma 35 | 2,597
subependymal giant cell astrocytoma 33 | 2,287
Breast cancer 32 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
malignant mesothelioma 28 | 3,232
invasive ductal carcinoma 27 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,989
non-small cell lung cancer 24 | 2,890
Bipolar Disorder 23 | 666
pancreatic cancer 23 | 2,398
pituitary cancer 23 | 1,972
Cancer 22 | 2,499
lung adenocarcinoma 22 | 2,716
Intellectual disability 19 | 1,016
Pick disease 19 | 1,894
cystic fibrosis 18 | 1,696
tuberculosis 17 | 2,010
ulcerative colitis 17 | 1,819
Autistic Disorder 16 | 364
Depressive disorder 16 | 409
Epilepsy 16 | 792
acute quadriplegic myopathy 16 | 1,158
interstitial cystitis 16 | 2,312
ductal carcinoma in situ 15 | 1,745
astrocytoma 14 | 1,146
group 4 medulloblastoma 14 | 1,855
pediatric high grade glioma 14 | 1,064
Duchenne muscular dystrophy 13 | 601
Melanoma 13 | 711
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 510
colon cancer 13 | 1,478
juvenile dermatomyositis 13 | 1,187
Seizures 12 | 596
adrenocortical carcinoma 12 | 1,428
breast carcinoma 12 | 1,638
Atopic dermatitis 11 | 952
Down syndrome 11 | 499
Mental Depression 11 | 333
Skin cancer 11 | 469
diabetes mellitus 11 | 1,728
Alzheimer's disease 10 | 658
Amyotrophic lateral sclerosis 10 | 451
Liver cancer 10 | 604
Major Depressive Disorder 10 | 301
spina bifida 10 | 1,074
Alcoholic Intoxication, Chronic 9 | 289
Autosomal recessive predisposition 9 | 1,442
Dull intelligence 9 | 645
Fragile X syndrome 9 | 34
Liver Cirrhosis, Experimental 9 | 769
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Mood Disorders 9 | 184
Neurodegenerative disease 9 | 414
Parkinson's disease 9 | 392
Poor school performance 9 | 645
Vascular disease 9 | 319
non primary Sjogren syndrome sicca 9 | 891
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
primary pancreatic ductal adenocarcinoma 9 | 1,109
Cognitive delay 8 | 608
Global developmental delay 8 | 608
Hypertension 8 | 396
Mental and motor retardation 8 | 608
Multiple myeloma 8 | 1,332
Rheumatoid arthritis 8 | 1,191
Unipolar Depression 8 | 250
Waldenstrons macroglobulinemia 8 | 765
esophageal adenocarcinoma 8 | 737
pancreatic carcinoma 8 | 562
Autism spectrum disorder 7 | 101
Chronic Lymphocytic Leukemia 7 | 262
Endometrial cancer 7 | 311
Heart disease 7 | 306
Muscle hypotonia 7 | 571
active Crohn's disease 7 | 922
aldosterone-producing adenoma 7 | 665
cutaneous lupus erythematosus 7 | 1,057
dermatomyositis 7 | 966
gastric cancer 7 | 459
mucosa-associated lymphoid tissue lymphoma 7 | 484

Tissue

Digestive Tract 117 | 17,369
Endocrine System 117 | 18,159
Female tissues 116 | 17,400
Nervous System 116 | 16,725
Male tissues 115 | 17,142
Skin and soft tissues 115 | 17,230
Liver and Pancreas 112 | 16,750
Urinary Tract 111 | 16,678
Blood and immune system 110 | 16,909
Respiratory system 109 | 16,393
Cardiovascular System 101 | 15,192

Target Family

Non-IDG 68 | 12,091
Enzyme 21 | 4,145
Ion Channel 11 | 344
GPCR 6 | 408
Kinase 5 | 634
Transporter 4 | 473
Epigenetic 2 | 242
Nuclear Receptor 1 | 48

GO Component

dendritic spine 118 | 118
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fragile X mental retardation syndrome-related protein 1 FXR1 Tbio Non-IDG -1.70770 50.9 220
Insulin-like growth factor 2 mRNA-binding protein 1 IGF2BP1 Tbio Non-IDG -1.85997 76.0 207
PH and SEC7 domain-containing protein 1 PSD Tbio Non-IDG -2.13025 139.8 20
Regulator of G-protein signaling 14 RGS14 Tbio Non-IDG -1.61170 43.9 233
Regulator of G-protein signaling 10 RGS10 Tbio Non-IDG -1.42892 32.0 146
Inward rectifier potassium channel 2 KCNJ2 Tchem Ion Channel -2.36978 224.8 221
Septin-11 SEPT11 Tbio Non-IDG -1.47747 32.4 127
FERM, ARHGEF and pleckstrin domain-containing protein 1 FARP1 Tbio Non-IDG -1.56544 38.3 153
F-box only protein 2 FBXO2 Tbio Non-IDG -1.36281 26.8 157
Metabotropic glutamate receptor 3 GRM3 Tchem GPCR -2.30964 186.9 274