Development Level

Tbio 8 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased circulating choleste... 2 | 93
abnormal behavioral response t... 1 | 66
abnormal cranium morphology 1 | 36
abnormal hair texture 1 | 4
abnormal incisor morphology 1 | 4
abnormal maxilla morphology 1 | 17
decreased body weight 1 | 161
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating total pr... 1 | 49
decreased lactate dehydrogenas... 1 | 16
decreased total body fat amoun... 1 | 207
increased circulating amylase ... 1 | 25
increased heart weight 1 | 62

Disease

Carcinoma 7 | 11,493
ovarian cancer 7 | 8,520
lung cancer 5 | 4,740
Multiple myeloma 4 | 1,332
invasive ductal carcinoma 3 | 2,951
osteosarcoma 3 | 7,950
psoriasis 3 | 6,694
Cancer 2 | 2,499
HIV Infections 2 | 102
Waldenstrons macroglobulinemia 2 | 765
diabetes mellitus 2 | 1,728
glioblastoma 2 | 5,792
non-small cell lung cancer 2 | 2,890
Acquired metabolic disease 1 | 336
Alveolar soft part sarcoma 1 | 10
Alzheimer Disease 1 | 83
Alzheimer's disease 1 | 658
Atopic dermatitis 1 | 952
Breast cancer 1 | 3,578
Cockayne syndrome 1 | 60
Congestive heart failure 1 | 113
Dementia 1 | 175
Hyperinsulinism 1 | 133
Kidney cancer 1 | 2,613
Photosensitive trichothiodystrophy 1 | 30
Schizophrenia 1 | 1,160
Stevens-Johnson syndrome 1 | 92
Type 2 diabetes mellitus 1 | 272
Vascular disease 1 | 319
astrocytic glioma 1 | 2,597
astrocytoma 1 | 1,146
atypical teratoid / rhabdoid tumor 1 | 5,112
dermatomyositis 1 | 966
ependymoma 1 | 4,679
group 3 medulloblastoma 1 | 4,104
hereditary spastic paraplegia 1 | 318
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
malignant mesothelioma 1 | 3,232
medulloblastoma, large-cell 1 | 6,241
oligodendroglioma 1 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
subependymal giant cell astrocytoma 1 | 2,287
substance-related disorder 1 | 162

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Enzyme 9 | 4,145

GO Component

cytosolic proteasome complex 9 | 9
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Insulin-degrading enzyme IDE Tchem Enzyme -2.57779 392.8 331
26S proteasome regulatory subunit 10B PSMC6 Tbio Enzyme -2.65165 339.0 214
26S proteasome non-ATPase regulatory subunit 14 PSMD14 Tbio Enzyme -1.80255 64.2 195
26S proteasome regulatory subunit 6A PSMC3 Tbio Enzyme -1.29086 19.3 302
Ubiquitin carboxyl-terminal hydrolase isozyme L5 UCHL5 Tbio Enzyme -1.71687 51.9 225
26S proteasome regulatory subunit 4 PSMC1 Tbio Enzyme -1.15617 13.5 118
26S proteasome regulatory subunit 8 PSMC5 Tbio Enzyme -1.70989 52.2 200
26S proteasome regulatory subunit 7 PSMC2 Tbio Enzyme -0.86409 7.23 212
26S proteasome regulatory subunit 6B PSMC4 Tbio Enzyme -1.55677 33.4 163