Development Level

Tbio 251 | 10,625
Tdark 47 | 7,003
Tchem 34 | 1,890
Tclin 11 | 602

Collection

Eligible Ion Channel Proteins 1 | 117
Eligible Kinase Proteins 1 | 134

IMPC Term

decreased total body fat amoun... 10 | 186
preweaning lethality, incomple... 9 | 260
decreased body weight 8 | 174
preweaning lethality, complete... 7 | 633
decreased bone mineral density 6 | 126
improved glucose tolerance 6 | 56
abnormal behavior 5 | 226
decreased bone mineral content 5 | 157
decreased circulating glucose ... 5 | 121
decreased lean body mass 5 | 195
increased lean body mass 5 | 107
increased or absent threshold ... 5 | 128
decreased circulating choleste... 4 | 85
decreased circulating triglyce... 4 | 83
increased circulating chloride... 4 | 43
abnormal coat appearance 3 | 25
abnormal embryo size 3 | 112
abnormal lens morphology 3 | 73
abnormal retina morphology 3 | 100
decreased body length 3 | 108
decreased circulating HDL chol... 3 | 77
decreased circulating insulin ... 3 | 75
decreased circulating iron lev... 3 | 25
decreased grip strength 3 | 123
decreased mean corpuscular vol... 3 | 50
decreased threshold for audito... 3 | 32
increased bone mineral content 3 | 92
increased mean corpuscular hem... 3 | 93
increased mean corpuscular vol... 3 | 91
male infertility 3 | 62
abnormal bone structure 2 | 131
abnormal head morphology 2 | 10
decreased CD4-positive, alpha ... 2 | 19
decreased T cell number 2 | 31
decreased circulating alanine ... 2 | 53
decreased circulating fructosa... 2 | 31
decreased circulating glycerol... 2 | 19
decreased circulating potassiu... 2 | 17
decreased circulating serum al... 2 | 79
decreased circulating total pr... 2 | 41
decreased erythrocyte cell num... 2 | 43
decreased fasted circulating g... 2 | 49
decreased lumbar vertebrae num... 2 | 62
decreased mean corpuscular hem... 2 | 34
decreased rib number 2 | 59
decreased startle reflex 2 | 48
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
hyperactivity 2 | 108
impaired righting response 2 | 19
increased body weight 2 | 42
increased circulating sodium l... 2 | 71
increased heart weight 2 | 37
increased rib number 2 | 41
thrombocytopenia 2 | 46
abnormal behavioral response t... 1 | 52
abnormal cranium morphology 1 | 32
abnormal kidney morphology 1 | 30
abnormal locomotor activation 1 | 26
abnormal optic disc morphology 1 | 10
abnormal testis morphology 1 | 30
abnormal thoracic vertebrae mo... 1 | 16
abnormal vertebrae morphology 1 | 14
abnormal vibrissa morphology 1 | 17
absent pinna reflex 1 | 21
decreased NK cell number 1 | 16
decreased caudal vertebrae num... 1 | 49
decreased cervical vertebrae n... 1 | 12
decreased circulating calcium ... 1 | 33
decreased circulating magnesiu... 1 | 11
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
female infertility 1 | 34
hypoactivity 1 | 89
increased CD4-positive NK T ce... 1 | 3
increased CD4-positive, CD25-p... 1 | 18
increased NK T cell number 1 | 11
increased blood uric acid leve... 1 | 5
increased body length 1 | 20
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating fructosa... 1 | 11
increased circulating iron lev... 1 | 25
increased circulating potassiu... 1 | 31
increased circulating total pr... 1 | 20
increased fasted circulating g... 1 | 68
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 19
increased memory-marker CD4-po... 1 | 3
increased sacral vertebrae num... 1 | 62
limb grasping 1 | 35
prenatal lethality 1 | 16
short tibia 1 | 82
small testis 1 | 37
stereotypic behavior 1 | 3
trunk curl 1 | 15

Disease

ovarian cancer 200 | 8,484
osteosarcoma 175 | 7,933
glioblastoma 154 | 5,572
psoriasis 147 | 6,685
medulloblastoma, large-cell 143 | 6,234
atypical teratoid / rhabdoid tumor 121 | 4,369
lung cancer 113 | 4,466
invasive ductal carcinoma 97 | 2,950
lung carcinoma 97 | 2,844
pilocytic astrocytoma 90 | 3,086
primitive neuroectodermal tumor 88 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 86 | 2,988
non-small cell lung cancer 85 | 2,798
intraductal papillary-mucinous adenoma (IPMA) 84 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 83 | 3,289
malignant mesothelioma 83 | 3,162
oligodendroglioma 81 | 2,849
Breast cancer 80 | 3,094
interstitial cystitis 78 | 2,299
pancreatic cancer 75 | 2,300
subependymal giant cell astrocytoma 75 | 2,287
pediatric high grade glioma 74 | 2,712
ependymoma 71 | 2,514
lung adenocarcinoma 69 | 2,713
Carcinoma 68 | 2,147
ulcerative colitis 62 | 2,087
astrocytic glioma 58 | 2,241
Pick disease 57 | 1,893
ductal carcinoma in situ 55 | 1,745
adult high grade glioma 54 | 2,148
Cancer 53 | 2,346
pituitary cancer 51 | 1,972
group 4 medulloblastoma 48 | 1,875
tuberculosis 48 | 1,557
astrocytoma 47 | 1,493
breast carcinoma 46 | 1,614
cystic fibrosis 45 | 1,665
colon cancer 43 | 1,475
group 3 medulloblastoma 43 | 2,254
medulloblastoma 43 | 1,524
primary pancreatic ductal adenocarcinoma 43 | 1,271
spina bifida 41 | 1,064
sonic hedgehog group medulloblastoma 40 | 1,482
adrenocortical carcinoma 39 | 1,427
posterior fossa group A ependymoma 38 | 1,511
posterior fossa group B ependymoma 38 | 1,530
acute quadriplegic myopathy 37 | 1,157
dermatomyositis 35 | 933
Rheumatoid Arthritis 34 | 1,160
juvenile dermatomyositis 34 | 1,189
diabetes mellitus 33 | 1,663
pancreatic ductal adenocarcinoma liver metastasis 33 | 1,795
Duchenne muscular dystrophy 32 | 602
Waldenstrons macroglobulinemia 32 | 765
atypical teratoid/rhabdoid tumor 32 | 1,095
cutaneous lupus erythematosus 31 | 1,056
nasopharyngeal carcinoma 30 | 1,056
Atopic dermatitis 29 | 944
esophageal adenocarcinoma 28 | 737
gastric carcinoma 27 | 832
active Crohn's disease 25 | 918
Multiple myeloma 22 | 1,327
primary Sjogren syndrome 22 | 789
Alzheimer's disease 19 | 644
active ulcerative colitis 19 | 477
acute myeloid leukemia 19 | 780
non primary Sjogren syndrome sicca 19 | 840
aldosterone-producing adenoma 18 | 664
mucosa-associated lymphoid tissue lymphoma 18 | 480
Parkinson's disease 17 | 364
autosomal dominant Emery-Dreifuss muscular dystrophy 17 | 499
progressive supranuclear palsy 17 | 674
Amyotrophic Lateral Sclerosis 16 | 431
Cardiomyopathy 16 | 110
Intellectual disability 16 | 573
tuberculosis and treatment for 6 months 16 | 686
hepatocellular carcinoma 15 | 532
Neurodegenerative disease 14 | 383
pancreatic carcinoma 14 | 567
Down syndrome 13 | 548
Obesity 13 | 616
gastric cancer 13 | 430
glioblastoma multiforme 13 | 347
Mammary Neoplasms 12 | 410
chronic rhinosinusitis 12 | 512
fibroadenoma 12 | 557
Cardiomyopathies 11 | 90
Kidney disease 11 | 396
Stomach Neoplasms 11 | 282
Chronic Lymphocytic Leukemia 10 | 242
Dilated cardiomyopathy 10 | 50
Peripheral Neuropathy 10 | 303
Substance-Related Disorders 10 | 114
hereditary spastic paraplegia 10 | 313
interstitial lung disease 10 | 291
tuberculosis and treatment for 3 months 10 | 327
Crohn's disease 9 | 304
Joubert syndrome 9 | 61
Nephronophthisis 9 | 74
Prostatic Neoplasms 9 | 471

Tissue

Digestive Tract 339 | 18,473
Female tissues 339 | 18,647
Nervous System 339 | 18,561
Endocrine System 338 | 18,512
Urinary Tract 338 | 18,444
Cardiovascular System 337 | 17,958
Liver and Pancreas 337 | 18,136
Male tissues 337 | 17,969
Skin and soft tissues 336 | 18,115
Blood and immune system 335 | 17,995
Respiratory system 328 | 17,484

Target Family

Non-IDG 256 | 11,971
Enzyme 55 | 4,146
Kinase 27 | 634
Ion Channel 2 | 341
Transporter 2 | 473
Nuclear Receptor 1 | 48

GO Component

cytoskeleton 343 | 343
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Wiskott-Aldrich syndrome protein family member 3 WASF3 Tbio Non-IDG -2.43045 280.1 123
Tyrosine-protein phosphatase non-receptor type 13 PTPN13 Tchem Enzyme -2.20613 177.9 120
F-actin-capping protein subunit alpha-1 CAPZA1 Tbio Non-IDG -1.28182 20.1 139
ERC protein 2 ERC2 Tbio Non-IDG -1.59613 39.1 32
Cysteine and glycine-rich protein 3 CSRP3 Tbio Non-IDG -1.95188 93.8 215
Protein phosphatase Slingshot homolog 1 SSH1 Tbio Enzyme -1.41770 25.0 106
Beta-1-syntrophin SNTB1 Tbio Non-IDG -1.02258 8.71 102
Cytoskeleton-associated protein 4 CKAP4 Tbio Non-IDG -1.40375 25.5 174
Tripartite motif-containing protein 67 TRIM67 Tdark Non-IDG -1.92838 86.9 22
Beta-actin-like protein 2 ACTBL2 Tdark Non-IDG -0.50618 4.39 46