Development Level

Tbio 266 | 11,445
Tdark 45 | 6,588
Tchem 29 | 1,598
Tclin 12 | 613

Collection

Kinase: IDG Consortium (Comple... 3 | 37
RFA-RM-18-021 2 | 328
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 16 | 979
preweaning lethality, incomple... 16 | 499
abnormal behavior 11 | 298
decreased total body fat amoun... 11 | 207
increased lean body mass 10 | 172
decreased body weight 7 | 161
hyperactivity 6 | 148
decreased bone mineral content 5 | 151
decreased bone mineral density 5 | 126
decreased circulating glucose ... 5 | 126
abnormal bone structure 4 | 187
decreased erythrocyte cell num... 4 | 62
decreased grip strength 4 | 116
decreased mean corpuscular vol... 4 | 79
improved glucose tolerance 4 | 79
increased circulating chloride... 4 | 41
increased mean corpuscular hem... 4 | 96
increased startle reflex 4 | 112
male infertility 4 | 123
abnormal behavioral response t... 3 | 66
abnormal coat-hair pigmentatio... 3 | 64
abnormal embryo size 3 | 220
abnormal seminal vesicle morph... 3 | 114
decreased body length 3 | 101
decreased circulating choleste... 3 | 93
decreased circulating triglyce... 3 | 79
decreased fasted circulating g... 3 | 65
decreased lean body mass 3 | 135
decreased mean corpuscular hem... 3 | 50
decreased vertical activity 3 | 208
increased heart weight 3 | 62
increased mean corpuscular vol... 3 | 92
increased total body fat amoun... 3 | 134
abnormal coat appearance 2 | 31
abnormal cornea morphology 2 | 31
abnormal head morphology 2 | 10
abnormal optic disc morphology 2 | 10
abnormal retina morphology 2 | 71
cataract 2 | 92
decreased circulating alanine ... 2 | 47
decreased circulating glycerol... 2 | 16
decreased circulating insulin ... 2 | 76
decreased circulating iron lev... 2 | 32
decreased circulating potassiu... 2 | 20
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased leukocyte cell numbe... 2 | 73
decreased startle reflex 2 | 75
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged lymph nodes 2 | 37
enlarged uterus 2 | 11
hydrometra 2 | 53
hypoactivity 2 | 132
impaired righting response 2 | 26
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased circulating alkaline... 2 | 122
increased circulating sodium l... 2 | 71
increased hemoglobin content 2 | 45
increased or absent threshold ... 2 | 101
increased vertical activity 2 | 24
pallor 2 | 34
prenatal lethality 2 | 28
small kidney 2 | 16
small superior vagus ganglion 2 | 74
small testis 2 | 58
thrombocytopenia 2 | 56
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal gait 1 | 69
abnormal hair growth 1 | 10
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
decreased T cell number 1 | 15
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating creatine... 1 | 4
decreased hematocrit 1 | 46
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
impaired pupillary reflex 1 | 26
increased blood uric acid leve... 1 | 5
increased body length 1 | 32
increased body weight 1 | 25
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased circulating total pr... 1 | 28
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased monocyte cell number 1 | 63
limb grasping 1 | 41
persistence of hyaloid vascula... 1 | 33
stereotypic behavior 1 | 3

Disease

Carcinoma 257 | 11,493
ovarian cancer 201 | 8,520
osteosarcoma 181 | 7,950
glioblastoma 158 | 5,792
psoriasis 147 | 6,694
atypical teratoid / rhabdoid tumor 141 | 5,112
medulloblastoma, large-cell 138 | 6,241
ependymoma 126 | 4,679
lung cancer 118 | 4,740
group 3 medulloblastoma 104 | 4,104
Breast cancer 97 | 3,578
invasive ductal carcinoma 96 | 2,951
lung carcinoma 95 | 2,843
adult high grade glioma 93 | 3,801
Astrocytoma, Pilocytic 87 | 3,081
non-small cell lung cancer 86 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 84 | 2,989
primitive neuroectodermal tumor 84 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 83 | 2,955
pancreatic cancer 83 | 2,398
malignant mesothelioma 82 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 81 | 3,291
oligodendroglioma 79 | 2,850
subependymal giant cell astrocytoma 77 | 2,287
Kidney cancer 76 | 2,613
interstitial cystitis 76 | 2,312
lung adenocarcinoma 67 | 2,716
tuberculosis 64 | 2,010
astrocytic glioma 61 | 2,597
Pick disease 58 | 1,894
ductal carcinoma in situ 56 | 1,745
ulcerative colitis 56 | 1,819
Cancer 55 | 2,499
pituitary cancer 54 | 1,972
breast carcinoma 46 | 1,638
colon cancer 44 | 1,478
cystic fibrosis 44 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 44 | 1,962
astrocytoma 42 | 1,146
group 4 medulloblastoma 42 | 1,855
spina bifida 42 | 1,074
acute quadriplegic myopathy 38 | 1,158
Autosomal recessive predisposition 37 | 1,442
adrenocortical carcinoma 36 | 1,428
juvenile dermatomyositis 36 | 1,187
dermatomyositis 35 | 966
primary pancreatic ductal adenocarcinoma 35 | 1,109
Rheumatoid arthritis 34 | 1,191
diabetes mellitus 34 | 1,728
pediatric high grade glioma 34 | 1,064
Duchenne muscular dystrophy 33 | 601
Waldenstrons macroglobulinemia 32 | 765
Intellectual disability 30 | 1,016
cutaneous lupus erythematosus 30 | 1,057
gastric carcinoma 29 | 807
nasopharyngeal carcinoma 29 | 1,058
esophageal adenocarcinoma 28 | 737
Liver Cirrhosis, Experimental 26 | 769
active Crohn's disease 26 | 922
active ulcerative colitis 26 | 764
Atopic dermatitis 25 | 952
Schizophrenia 23 | 1,160
Multiple myeloma 22 | 1,332
acute myeloid leukemia 21 | 783
primary Sjogren syndrome 21 | 735
non primary Sjogren syndrome sicca 20 | 891
Dull intelligence 19 | 645
Low intelligence 19 | 645
Melanoma 19 | 711
Mental Retardation 19 | 645
Mental deficiency 19 | 645
Poor school performance 19 | 645
mucosa-associated lymphoid tissue lymphoma 19 | 484
sonic hedgehog group medulloblastoma 19 | 467
Alzheimer's disease 18 | 658
Liver cancer 18 | 604
Muscle hypotonia 18 | 571
Parkinson's disease 18 | 392
aldosterone-producing adenoma 18 | 665
Cognitive delay 17 | 608
Global developmental delay 17 | 608
Mental and motor retardation 17 | 608
Neurodegenerative disease 17 | 414
autosomal dominant Emery-Dreifuss muscular dystrophy 17 | 510
hepatocellular carcinoma 16 | 547
progressive supranuclear palsy 16 | 676
Cardiomyopathy 15 | 116
gastric cancer 15 | 459
pancreatic carcinoma 15 | 562
Amyotrophic lateral sclerosis 14 | 451
Bipolar Disorder 13 | 666
Cerebellar Ataxia 13 | 304
Down syndrome 13 | 499
Kidney disease 13 | 430
Skin cancer 13 | 469
Epilepsy 12 | 792
Mammary Neoplasms 12 | 425
Obesity 12 | 678
atypical teratoid/rhabdoid tumor 12 | 357
fibroadenoma 12 | 559

Tissue

Endocrine System 347 | 18,159
Female tissues 338 | 17,400
Male tissues 336 | 17,142
Skin and soft tissues 336 | 17,230
Digestive Tract 334 | 17,369
Nervous System 334 | 16,725
Blood and immune system 330 | 16,909
Urinary Tract 330 | 16,678
Liver and Pancreas 329 | 16,750
Respiratory system 322 | 16,393
Cardiovascular System 306 | 15,192

Target Family

Non-IDG 268 | 12,091
Enzyme 51 | 4,145
Kinase 27 | 634
Ion Channel 3 | 344
Transporter 2 | 473
Nuclear Receptor 1 | 48

GO Component

cytoskeleton 352 | 352
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tensin-1 TNS1 Tbio Non-IDG -2.74141 354.5 133
Radial spoke head protein 3 homolog RSPH3 Tdark Non-IDG -1.14197 12.4 28
Proline-serine-threonine phosphatase-interacting protein 1 PSTPIP1 Tbio Enzyme -1.89883 82.3 119
Serine protease HTRA2, mitochondrial HTRA2 Tbio Enzyme -2.60032 392.5 519
Putative beta-actin-like protein 3 POTEKP Tdark Non-IDG -0.19266 2.15 0
FERM domain-containing protein 8 FRMD8 Tdark Non-IDG 0.48 0.20 104
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 MACF1 Tbio Non-IDG -2.05246 115.8 45
Epsilon-sarcoglycan SGCE Tbio Non-IDG -2.19042 158.3 93
Thymosin beta-15B TMSB15B Tdark Non-IDG -0.96314 17.3 9
Thymosin beta-15A TMSB15B Tdark Non-IDG -0.96314 17.3 40