Development Level

Tbio 94 | 11,445
Tchem 17 | 1,598
Tdark 14 | 6,588
Tclin 8 | 613

Collection

RFA-RM-18-021 6 | 328
GPCR: IDG Consortium (Targets) 4 | 126
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, incomple... 7 | 499
preweaning lethality, complete... 5 | 979
decreased leukocyte cell numbe... 3 | 73
abnormal embryo size 2 | 220
decreased circulating triglyce... 2 | 79
decreased vertical activity 2 | 208
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased hematocrit 2 | 46
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal coat appearance 1 | 31
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal eye anterior chamber ... 1 | 9
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal limb morphology 1 | 13
abnormal liver morphology 1 | 17
abnormal motor capabilities-co... 1 | 5
abnormal outer ear morphology 1 | 3
abnormal pelvic girdle bone mo... 1 | 12
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
abnormal stomach morphology 1 | 10
abnormal vertebrae morphology 1 | 18
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
cyanosis 1 | 7
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
female infertility 1 | 60
hemorrhage 1 | 23
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
increased IgG2b level 1 | 1
increased circulating HDL chol... 1 | 80
increased circulating aspartat... 1 | 15
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased heart weight 1 | 62
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
thrombocytopenia 1 | 56

Disease

Carcinoma 82 | 11,493
ovarian cancer 79 | 8,520
osteosarcoma 69 | 7,950
medulloblastoma, large-cell 68 | 6,241
atypical teratoid / rhabdoid tumor 64 | 5,112
glioblastoma 61 | 5,792
adult high grade glioma 47 | 3,801
ependymoma 46 | 4,679
psoriasis 45 | 6,694
Breast cancer 36 | 3,578
lung cancer 35 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,291
primitive neuroectodermal tumor 34 | 3,035
Astrocytoma, Pilocytic 33 | 3,081
astrocytic glioma 32 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 32 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,955
oligodendroglioma 31 | 2,850
group 3 medulloblastoma 29 | 4,104
group 4 medulloblastoma 26 | 1,855
lung adenocarcinoma 26 | 2,716
pancreatic cancer 26 | 2,398
tuberculosis 26 | 2,010
interstitial cystitis 25 | 2,312
invasive ductal carcinoma 25 | 2,951
malignant mesothelioma 25 | 3,232
Kidney cancer 23 | 2,613
lung carcinoma 23 | 2,843
non-small cell lung cancer 22 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,962
Pick disease 20 | 1,894
ductal carcinoma in situ 20 | 1,745
subependymal giant cell astrocytoma 20 | 2,287
breast carcinoma 16 | 1,638
gastric carcinoma 16 | 807
pituitary cancer 16 | 1,972
primary pancreatic ductal adenocarcinoma 16 | 1,109
ulcerative colitis 16 | 1,819
Schizophrenia 14 | 1,160
dermatomyositis 13 | 966
acute quadriplegic myopathy 12 | 1,158
non primary Sjogren syndrome sicca 12 | 891
Cancer 11 | 2,499
Liver Cirrhosis, Experimental 11 | 769
cystic fibrosis 11 | 1,696
diabetes mellitus 11 | 1,728
esophageal adenocarcinoma 11 | 737
juvenile dermatomyositis 11 | 1,187
spina bifida 11 | 1,074
Bipolar Disorder 10 | 666
adrenocortical carcinoma 10 | 1,428
colon cancer 10 | 1,478
Alzheimer's disease 9 | 658
Intellectual disability 9 | 1,016
Multiple myeloma 9 | 1,332
mucosa-associated lymphoid tissue lymphoma 9 | 484
Amyotrophic lateral sclerosis 8 | 451
Autosomal recessive predisposition 8 | 1,442
Epilepsy 8 | 792
Liver cancer 8 | 604
Parkinson's disease 8 | 392
Waldenstrons macroglobulinemia 8 | 765
astrocytoma 8 | 1,146
medulloblastoma 8 | 720
pediatric high grade glioma 8 | 1,064
Duchenne muscular dystrophy 7 | 601
Rheumatoid arthritis 7 | 1,191
aldosterone-producing adenoma 7 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
cutaneous lupus erythematosus 7 | 1,057
fibroadenoma 7 | 559
posterior fossa group A ependymoma 7 | 468
progressive supranuclear palsy 7 | 676
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Mental and motor retardation 6 | 608
Muscle hypotonia 6 | 571
Type 2 diabetes mellitus 6 | 272
acute myeloid leukemia 6 | 783
nasopharyngeal carcinoma 6 | 1,058
Alcoholic Intoxication, Chronic 5 | 289
Autistic Disorder 5 | 364
Becker muscular dystrophy 5 | 191
Cerebral Ischemia 5 | 37
Diarrhea 5 | 253
Down syndrome 5 | 499
Huntington's disease 5 | 76
Irritable bowel syndrome 5 | 60
Neurodegenerative disease 5 | 414
active Crohn's disease 5 | 922
active ulcerative colitis 5 | 764
chronic rhinosinusitis 5 | 512
hepatocellular carcinoma 5 | 547
hereditary spastic paraplegia 5 | 318
limb girdle muscular dystrophy 2A 5 | 213
sarcoidosis 5 | 370
sonic hedgehog group medulloblastoma 5 | 467
Atopic dermatitis 4 | 952
Depressive disorder 4 | 409
Hypertension 4 | 396

Tissue

Endocrine System 132 | 18,159
Digestive Tract 131 | 17,369
Female tissues 130 | 17,400
Liver and Pancreas 129 | 16,750
Male tissues 129 | 17,142
Nervous System 129 | 16,725
Skin and soft tissues 127 | 17,230
Urinary Tract 127 | 16,678
Blood and immune system 126 | 16,909
Cardiovascular System 122 | 15,192
Respiratory system 122 | 16,393

Target Family

Non-IDG 83 | 12,091
Enzyme 26 | 4,145
Ion Channel 11 | 344
GPCR 6 | 408
Kinase 4 | 634
Transporter 3 | 473

GO Component

cytoplasmic vesicle membrane 133 | 133
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CAP-Gly domain-containing linker protein 1 CLIP1 Tbio Non-IDG -2.54943 343.7 221
Transient receptor potential cation channel subfamily M member 2 TRPM2 Tchem Ion Channel -1.34318 25.1 209
Calcium-dependent secretion activator 2 CADPS2 Tbio Non-IDG -1.18033 15.0 36
Protein spire homolog 2 SPIRE2 Tbio Non-IDG -0.76971 5.22 91
Serine/threonine-protein kinase TAO2 TAOK2 Tchem Kinase -1.52454 36.1 154
Sorting nexin-5 SNX5 Tbio Non-IDG -1.23706 20.8 141
Probable palmitoyltransferase ZDHHC8 ZDHHC8 Tbio Enzyme -1.30633 19.3 116
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
Lysosome-associated membrane glycoprotein 5 LAMP5 Tbio Non-IDG -0.81661 7.67 83