Development Level

Tbio 81 | 10,625
Tdark 23 | 7,003
Tchem 17 | 1,890
Tclin 4 | 602

Collection

GPCR: IDG Consortium (Targets) 3 | 128
Ion Channel: IDG Consortium (Targets) 1 | 102
Kinase: IDG Consortium (Complete/Control) 1 | 37
Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, complete... 4 | 633
increased mean corpuscular vol... 3 | 91
preweaning lethality, incomple... 3 | 260
decreased circulating glucose ... 2 | 121
decreased threshold for audito... 2 | 32
improved glucose tolerance 2 | 56
increased circulating alkaline... 2 | 119
increased hematocrit 2 | 36
increased mean corpuscular hem... 2 | 93
increased or absent threshold ... 2 | 128
abnormal behavioral response t... 1 | 52
abnormal coat appearance 1 | 25
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal eye anterior chamber ... 1 | 3
abnormal facial morphology 1 | 9
abnormal head shape 1 | 4
abnormal limb morphology 1 | 7
abnormal motor capabilities-co... 1 | 4
abnormal outer ear morphology 1 | 1
abnormal pelvic girdle bone mo... 1 | 11
abnormal posture 1 | 5
abnormal retina morphology 1 | 100
abnormal skin morphology 1 | 23
abnormal vertebrae morphology 1 | 14
absent startle reflex 1 | 15
absent vibrissae 1 | 14
cardiovascular system phenotyp... 1 | 35
cyanosis 1 | 6
decreased CD8-positive, alpha-... 1 | 26
decreased NK T cell number 1 | 28
decreased T cell number 1 | 31
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating choleste... 1 | 85
decreased circulating fructosa... 1 | 31
decreased circulating potassiu... 1 | 17
decreased circulating serum al... 1 | 79
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased fasted circulating g... 1 | 49
decreased gamma-delta T cell n... 1 | 18
decreased grip strength 1 | 123
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
decreased prepulse inhibition 1 | 52
decreased rib number 1 | 59
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
decreased total retina thickne... 1 | 20
enlarged epididymis 1 | 27
enlarged lymph nodes 1 | 27
female infertility 1 | 34
hemorrhage 1 | 12
hydrops fetalis 1 | 22
hyperactivity 1 | 108
increased CD8-positive, alpha-... 1 | 11
increased body weight 1 | 42
increased circulating aspartat... 1 | 17
increased circulating chloride... 1 | 43
increased circulating glucose ... 1 | 16
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 68
increased heart rate 1 | 17
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 25
increased neutrophil cell numb... 1 | 15
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
shortened ST segment 1 | 9
straub tail 1 | 26
thrombocytopenia 1 | 46

Disease

ovarian cancer 76 | 8,491
osteosarcoma 66 | 7,933
medulloblastoma, large-cell 62 | 6,234
glioblastoma 53 | 5,572
atypical teratoid / rhabdoid tumor 50 | 4,369
psoriasis 44 | 6,685
lung cancer 34 | 4,473
intraductal papillary-mucinous carcinoma (IPMC) 30 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 30 | 3,289
pilocytic astrocytoma 30 | 3,086
Breast cancer 29 | 3,098
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,956
pediatric high grade glioma 29 | 2,712
primitive neuroectodermal tumor 29 | 3,031
oligodendroglioma 26 | 2,849
pancreatic cancer 26 | 2,300
lung adenocarcinoma 24 | 2,714
malignant mesothelioma 24 | 3,163
invasive ductal carcinoma 23 | 2,950
tuberculosis 23 | 1,563
interstitial cystitis 22 | 2,299
astrocytic glioma 21 | 2,241
group 4 medulloblastoma 21 | 1,875
lung carcinoma 20 | 2,844
non-small cell lung cancer 20 | 2,798
adult high grade glioma 19 | 2,148
ependymoma 18 | 2,514
primary pancreatic ductal adenocarcinoma 18 | 1,271
subependymal giant cell astrocytoma 18 | 2,287
Pick disease 17 | 1,893
ductal carcinoma in situ 17 | 1,745
medulloblastoma 17 | 1,524
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,795
posterior fossa group A ependymoma 17 | 1,511
astrocytoma 15 | 1,493
pituitary cancer 15 | 1,972
sonic hedgehog group medulloblastoma 15 | 1,482
ulcerative colitis 15 | 2,087
Carcinoma 14 | 2,147
gastric carcinoma 14 | 832
breast carcinoma 13 | 1,614
posterior fossa group B ependymoma 13 | 1,530
acute quadriplegic myopathy 12 | 1,157
dermatomyositis 12 | 966
Cancer 11 | 2,346
colon cancer 11 | 1,475
diabetes mellitus 11 | 1,663
juvenile dermatomyositis 11 | 1,189
spina bifida 11 | 1,064
Multiple myeloma 10 | 1,327
cystic fibrosis 10 | 1,670
esophageal adenocarcinoma 10 | 737
group 3 medulloblastoma 10 | 2,254
Rheumatoid Arthritis 9 | 1,170
adrenocortical carcinoma 9 | 1,427
atypical teratoid/rhabdoid tumor 9 | 1,095
Alzheimer's disease 8 | 644
Amyotrophic Lateral Sclerosis 8 | 432
Waldenstrons macroglobulinemia 8 | 764
mucosa-associated lymphoid tissue lymphoma 8 | 480
Duchenne muscular dystrophy 7 | 602
aldosterone-producing adenoma 7 | 664
non primary Sjogren syndrome sicca 7 | 840
acute myeloid leukemia 6 | 785
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
cutaneous lupus erythematosus 6 | 1,056
fibroadenoma 6 | 557
nasopharyngeal carcinoma 6 | 1,056
progressive supranuclear palsy 6 | 674
Down syndrome 5 | 548
Huntington's disease 5 | 72
Intellectual disability 5 | 573
Neurodegenerative disease 5 | 383
Parkinson's disease 5 | 364
active ulcerative colitis 5 | 477
chronic rhinosinusitis 5 | 512
tuberculosis and treatment for 6 months 5 | 686
Atopic dermatitis 4 | 944
Becker muscular dystrophy 4 | 187
Dementia 4 | 129
IGA Glomerulonephritis 4 | 454
Schizophrenia 4 | 503
Type 2 diabetes mellitus 4 | 192
active Crohn's disease 4 | 918
hepatocellular carcinoma 4 | 550
hereditary spastic paraplegia 4 | 313
limb girdle muscular dystrophy 2A 4 | 156
primary Sjogren syndrome 4 | 788
sarcoidosis 4 | 368
Bipolar Disorder 3 | 266
Diabetes Mellitus, Non-Insulin-Dependent 3 | 161
Joubert syndrome 3 | 62
Multiple Sclerosis 3 | 498
Obesity 3 | 616
Polycystic Ovary Syndrome 3 | 334
Toxic encephalopathy 3 | 131
head and neck cancer and chronic obstructive pulmonary disease 3 | 237
inflammatory breast cancer 3 | 404
pancreatic carcinoma 3 | 567
urothelial carcinoma 3 | 318

Tissue

Nervous System 125 | 18,560
Cardiovascular System 124 | 17,957
Digestive Tract 124 | 18,472
Endocrine System 124 | 18,511
Female tissues 124 | 18,646
Liver and Pancreas 124 | 18,135
Male tissues 124 | 17,968
Respiratory system 124 | 17,483
Skin and soft tissues 124 | 18,114
Urinary Tract 124 | 18,443
Blood and immune system 123 | 17,994

Target Family

Non-IDG 81 | 11,969
Enzyme 27 | 4,146
GPCR 5 | 408
Ion Channel 5 | 341
Kinase 4 | 634
Transporter 3 | 473

GO Component

cytoplasmic vesicle membrane 125 | 125
nucleus 5,106 | 5,106
cytoplasm 4,984 | 4,984
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,264 | 3,264
extracellular exosome 2,757 | 2,757
nucleoplasm 2,716 | 2,716
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 536 | 536
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Huntingtin HTT Tchem Non-IDG -3.32908 2140.8 521
Small cell adhesion glycoprotein SMAGP Tdark Non-IDG 0.00000 1.85 72
14-3-3 protein zeta/delta YWHAZ Tbio Non-IDG -2.55872 362.3 648
Glycerophosphodiester phosphodiesterase 1 GDE1 Tbio Enzyme -1.03941 11.9 104
AP-1 complex subunit mu-1 AP1M1 Tbio Non-IDG -1.18893 12.9 104
Solute carrier family 26 member 6 SLC26A6 Tbio Ion Channel -1.85864 67.8 85
Charged multivesicular body protein 4a CHMP4A Tbio Non-IDG -1.11491 14.8 25
Ras-related protein Rab-11A RAB11A Tbio Enzyme -2.62399 398.9 288
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.87621 876.7 339
Ras-related protein Rab-13 RAB13 Tbio Enzyme -1.38773 26.2 55