Development Level

Tbio 37 | 11,651
Tchem 5 | 1,388
Tdark 2 | 6,593

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 3 | 979
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal cornea morphology 1 | 31
abnormal femur morphology 1 | 14
abnormal locomotor behavior 1 | 24
abnormal skin condition 1 | 6
abnormal spine curvature 1 | 9
decreased IgE level 1 | 6
decreased basophil cell number 1 | 16
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased mean corpuscular vol... 1 | 79
hypoactivity 1 | 132
increased body temperature 1 | 9
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased spleen weight 1 | 10
prenatal lethality 1 | 28
small testis 1 | 58
thrombocytopenia 1 | 56
thrombocytosis 1 | 27
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 29 | 11,493
ovarian cancer 29 | 8,520
osteosarcoma 24 | 7,950
psoriasis 17 | 6,694
Breast cancer 13 | 3,578
Kidney cancer 13 | 2,613
lung adenocarcinoma 13 | 2,716
Cancer 12 | 2,499
atypical teratoid / rhabdoid tumor 12 | 5,112
lung cancer 12 | 4,740
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
medulloblastoma, large-cell 11 | 6,241
Multiple myeloma 10 | 1,332
adult high grade glioma 10 | 3,801
glioblastoma 10 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
invasive ductal carcinoma 10 | 2,951
dermatomyositis 9 | 966
ependymoma 9 | 4,679
oligodendroglioma 8 | 2,850
astrocytoma 7 | 1,146
group 3 medulloblastoma 7 | 4,104
group 4 medulloblastoma 7 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
pancreatic cancer 7 | 2,398
subependymal giant cell astrocytoma 7 | 2,287
Pick disease 6 | 1,894
Waldenstrons macroglobulinemia 6 | 765
acute quadriplegic myopathy 6 | 1,158
astrocytic glioma 6 | 2,597
malignant mesothelioma 6 | 3,232
primitive neuroectodermal tumor 6 | 3,035
Amyotrophic lateral sclerosis 5 | 451
Schizophrenia 5 | 1,160
cystic fibrosis 5 | 1,696
juvenile dermatomyositis 5 | 1,187
primary pancreatic ductal adenocarcinoma 5 | 1,109
progressive supranuclear palsy 5 | 676
ulcerative colitis 5 | 1,819
Spinocerebellar ataxia type 2 4 | 23
breast carcinoma 4 | 1,638
hepatocellular carcinoma 4 | 547
non primary Sjogren syndrome sicca 4 | 891
non-small cell lung cancer 4 | 2,890
pituitary cancer 4 | 1,972
spina bifida 4 | 1,074
tuberculosis 4 | 2,010
Alzheimer's disease 3 | 658
Astrocytoma, Pilocytic 3 | 3,081
Breast Neoplasms 3 | 445
Gaucher disease type 1 3 | 180
Intellectual disability 3 | 1,016
Mammary Neoplasms 3 | 425
Neoplasm Invasiveness 3 | 161
Neurodegenerative disease 3 | 414
Rheumatoid arthritis 3 | 1,191
adrenocortical carcinoma 3 | 1,428
aldosterone-producing adenoma 3 | 665
colon cancer 3 | 1,478
gastric cancer 3 | 459
lung carcinoma 3 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
relapsing-remitting multiple sclerosis 3 | 18
tuberculosis and treatment for 3 months 3 | 179
Anxiety 2 | 136
Anxiety disease 2 | 113
Arthritis 2 | 290
Dementia 2 | 175
Distal amyotrophy 2 | 51
Down syndrome 2 | 499
Dull intelligence 2 | 645
Fragile X syndrome 2 | 34
Liver Cirrhosis, Experimental 2 | 769
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Muscle Spasticity 2 | 195
Muscle hypotonia 2 | 571
Myocardial Ischemia 2 | 169
Nerve Degeneration 2 | 121
Neurodevelopmental Disorders 2 | 70
Parkinson's disease 2 | 392
Poor school performance 2 | 645
Primary biliary cirrhosis 2 | 51
Renal Cell Carcinoma 2 | 214
Vasculitis 2 | 80
acute myeloid leukemia 2 | 783
atypical teratoid/rhabdoid tumor 2 | 357
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
hereditary spastic paraplegia 2 | 318
inflammatory breast cancer 2 | 286
interstitial cystitis 2 | 2,312
interstitial lung disease 2 | 298
mucosa-associated lymphoid tissue lymphoma 2 | 484
nasopharyngeal carcinoma 2 | 1,058
pancreatic carcinoma 2 | 562
posterior fossa group B ependymoma 2 | 416
primary Sjogren syndrome 2 | 735
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 43 | 16,909
Digestive Tract 43 | 17,369
Endocrine System 43 | 18,159
Female tissues 43 | 17,400
Liver and Pancreas 43 | 16,750
Respiratory system 43 | 16,393
Male tissues 42 | 17,142
Nervous System 42 | 16,725
Skin and soft tissues 42 | 17,230
Urinary Tract 42 | 16,678
Cardiovascular System 41 | 15,192

Target Family

Non-IDG 35 | 12,091
Enzyme 6 | 4,145
Transcription Factor 2 | 1,400
Kinase 1 | 634

GO Component

cytoplasmic stress granule 44 | 44
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleolysin TIA-1 isoform p40 TIA1 Tbio Non-IDG -2.86461 714.2 314
Eukaryotic translation initiation factor 2 subunit 1 EIF2S1 Tbio Non-IDG -2.81111 643.5 577
Double-stranded RNA-binding protein Staufen homolog 1 STAU1 Tbio Non-IDG -2.24156 174.1 258
RNA-binding protein 4 RBM4 Tbio Non-IDG -1.71130 51.9 162
RNA-binding protein with multiple splicing RBPMS Tbio Non-IDG -2.12771 131.9 266
Probable ATP-dependent RNA helicase DDX6 DDX6 Tbio Enzyme -1.81481 65.6 302
MAPK regulated corepressor interacting protein 2 MCRIP2 Tdark Non-IDG 0.70 0.05 13
Ataxin-2 ATXN2 Tbio Non-IDG -2.32523 224.6 194
mRNA decay activator protein ZFP36 ZFP36 Tbio Non-IDG -2.42848 236.6 0
Nuclear fragile X mental retardation-interacting protein 2 NUFIP2 Tbio Non-IDG -0.80133 5.62 70