Development Level

Tbio 31 | 11,651
Tchem 9 | 1,388
Tclin 4 | 612

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 4 | 499
abnormal bone structure 3 | 187
abnormal embryo size 3 | 220
abnormal seminal vesicle morph... 2 | 114
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
increased startle reflex 2 | 112
abnormal behavior 1 | 298
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal sleep behavior 1 | 70
abnormal vibrissa morphology 1 | 25
absent vibrissae 1 | 12
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 36
decreased coping response 1 | 8
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged heart 1 | 210
impaired righting response 1 | 26
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 34 | 11,493
ovarian cancer 25 | 8,520
osteosarcoma 22 | 7,950
lung cancer 20 | 4,740
psoriasis 20 | 6,694
glioblastoma 17 | 5,792
medulloblastoma, large-cell 17 | 6,241
atypical teratoid / rhabdoid tumor 15 | 5,112
Breast cancer 14 | 3,578
Cancer 14 | 2,499
adult high grade glioma 14 | 3,801
malignant mesothelioma 14 | 3,232
ependymoma 12 | 4,679
subependymal giant cell astrocytoma 11 | 2,287
Astrocytoma, Pilocytic 10 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
oligodendroglioma 10 | 2,850
pituitary cancer 10 | 1,972
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
lung adenocarcinoma 9 | 2,716
lung carcinoma 9 | 2,843
non-small cell lung cancer 9 | 2,890
primitive neuroectodermal tumor 9 | 3,035
tuberculosis 9 | 2,010
Autosomal recessive predisposition 8 | 1,442
Kidney cancer 8 | 2,613
Pick disease 8 | 1,894
astrocytic glioma 8 | 2,597
group 3 medulloblastoma 8 | 4,104
interstitial cystitis 8 | 2,312
invasive ductal carcinoma 8 | 2,951
Schizophrenia 7 | 1,160
breast carcinoma 7 | 1,638
colon cancer 7 | 1,478
pancreatic cancer 7 | 2,398
ulcerative colitis 7 | 1,819
Multiple myeloma 6 | 1,332
adrenocortical carcinoma 6 | 1,428
cutaneous lupus erythematosus 6 | 1,057
cystic fibrosis 6 | 1,696
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Breast Neoplasms 5 | 445
Hypertension 5 | 396
Mammary Neoplasms 5 | 425
Melanoma 5 | 711
Parkinson's disease 5 | 392
Rheumatoid arthritis 5 | 1,191
dermatomyositis 5 | 966
non primary Sjogren syndrome sicca 5 | 891
primary Sjogren syndrome 5 | 735
spina bifida 5 | 1,074
Bipolar Disorder 4 | 666
Cataract 4 | 297
Epilepsy 4 | 792
Hypertensive disease 4 | 292
Intellectual disability 4 | 1,016
Malaria 4 | 160
Obesity 4 | 678
Palmoplantar keratosis 4 | 74
Prostatic Neoplasms 4 | 495
Stomach Neoplasms 4 | 300
esophageal adenocarcinoma 4 | 737
gastric cancer 4 | 459
juvenile dermatomyositis 4 | 1,187
Abnormality of metabolism/homeostasis 3 | 134
Adenoid Cystic Carcinoma 3 | 99
Alcoholic Intoxication, Chronic 3 | 289
Anemia 3 | 365
Arthritis 3 | 290
Arthritis, Rheumatoid 3 | 174
Carcinoma, Adenoid Cystic 3 | 99
Cognitive delay 3 | 608
Down syndrome 3 | 499
Duchenne muscular dystrophy 3 | 601
Fatigue 3 | 182
Gaucher disease type 1 3 | 180
Global developmental delay 3 | 608
LEOPARD syndrome 3 | 20
Major Depressive Disorder 3 | 301
Mental and motor retardation 3 | 608
Multiple Sclerosis 3 | 540
Muscle hypotonia 3 | 571
Myocardial Infarction 3 | 151
Nausea and vomiting 3 | 97
Renal Cell Carcinoma 3 | 214
Short stature 3 | 531
Skin cancer 3 | 469
Unipolar Depression 3 | 250
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
astrocytoma 3 | 1,146
diabetes mellitus 3 | 1,728
ductal carcinoma in situ 3 | 1,745
hepatocellular carcinoma 3 | 547
primary pancreatic ductal adenocarcinoma 3 | 1,109
Carcinoma, Hepatocellular 2 | 228
Disease Progression 2 | 136
Liver carcinoma 2 | 240

Tissue

Blood and immune system 44 | 16,909
Digestive Tract 44 | 17,369
Endocrine System 44 | 18,159
Nervous System 44 | 16,725
Skin and soft tissues 44 | 17,230
Female tissues 43 | 17,400
Liver and Pancreas 43 | 16,750
Male tissues 43 | 17,142
Urinary Tract 43 | 16,678
Cardiovascular System 41 | 15,192
Respiratory system 41 | 16,393

Target Family

Non-IDG 22 | 12,091
Enzyme 14 | 4,145
Kinase 4 | 634
GPCR 1 | 408
Ion Channel 1 | 344
Transcription Factor 1 | 1,400
Transporter 1 | 473

GO Component

cytoplasmic side of plasma mem... 44 | 44
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Desmoglein-1 DSG1 Tbio Non-IDG -2.72159 516.2 406
Ganglioside GM2 activator GM2A Tbio Non-IDG -2.03952 111.9 325
Lipopolysaccharide-induced tumor necrosis factor-alpha factor LITAF Tbio Transcription Factor -2.03585 113.9 202
TNF receptor-associated factor 6 TRAF6 Tbio Non-IDG -2.74221 511.1 403
Neurotensin receptor type 1 NTSR1 Tchem GPCR -2.94526 841.8 215
Guanine nucleotide-binding protein subunit beta-like protein 1 GNB1L Tbio Non-IDG -1.88405 77.1 60
Tyrosine-protein phosphatase non-receptor type 22 PTPN22 Tchem Enzyme -2.70715 543.9 211
Regulator of G-protein signaling 2 RGS2 Tbio Non-IDG -2.36297 251.2 199
Baculoviral IAP repeat-containing protein 2 BIRC2 Tchem Non-IDG -2.53423 308.7 351