Development Level

Tbio 50 | 11,445
Tchem 6 | 1,598
Tclin 3 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 4 | 499
decreased grip strength 3 | 116
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased prepulse inhibition 2 | 82
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased grip strength 2 | 41
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal motor learning 1 | 3
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal vitreous body morphol... 1 | 10
abnormal vocalization 1 | 21
absent startle reflex 1 | 24
cataract 1 | 92
convulsive seizures 1 | 13
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased urine creatinine lev... 1 | 3
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged kidney 1 | 14
hypoactivity 1 | 132
increased body length 1 | 32
increased circulating alkaline... 1 | 122
increased erythrocyte cell num... 1 | 39
increased heart rate 1 | 23
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
pallor 1 | 34
polycystic kidney 1 | 15
shortened RR interval 1 | 17
thrombocytopenia 1 | 56

Disease

Carcinoma 41 | 11,493
ovarian cancer 34 | 8,520
osteosarcoma 32 | 7,950
medulloblastoma, large-cell 25 | 6,241
psoriasis 24 | 6,694
atypical teratoid / rhabdoid tumor 20 | 5,112
glioblastoma 19 | 5,792
lung cancer 19 | 4,740
group 3 medulloblastoma 18 | 4,104
ependymoma 16 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
Cancer 15 | 2,499
Astrocytoma, Pilocytic 14 | 3,081
Multiple myeloma 13 | 1,332
adult high grade glioma 13 | 3,801
oligodendroglioma 13 | 2,850
malignant mesothelioma 12 | 3,232
primitive neuroectodermal tumor 12 | 3,035
subependymal giant cell astrocytoma 12 | 2,287
astrocytic glioma 11 | 2,597
lung adenocarcinoma 11 | 2,716
Breast cancer 10 | 3,578
Kidney cancer 10 | 2,613
adrenocortical carcinoma 10 | 1,428
interstitial cystitis 9 | 2,312
invasive ductal carcinoma 9 | 2,951
lung carcinoma 9 | 2,843
Waldenstrons macroglobulinemia 8 | 765
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
juvenile dermatomyositis 8 | 1,187
non-small cell lung cancer 8 | 2,890
pancreatic cancer 8 | 2,398
tuberculosis 8 | 2,010
Rheumatoid arthritis 7 | 1,191
active ulcerative colitis 7 | 764
acute quadriplegic myopathy 7 | 1,158
cystic fibrosis 7 | 1,696
dermatomyositis 7 | 966
Amyotrophic lateral sclerosis 6 | 451
Duchenne muscular dystrophy 6 | 601
Intellectual disability 6 | 1,016
colon cancer 6 | 1,478
cutaneous lupus erythematosus 6 | 1,057
diabetes mellitus 6 | 1,728
pediatric high grade glioma 6 | 1,064
pituitary cancer 6 | 1,972
Depressive disorder 5 | 409
Epilepsy 5 | 792
Pick disease 5 | 1,894
astrocytoma 5 | 1,146
atypical teratoid/rhabdoid tumor 5 | 357
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
nasopharyngeal carcinoma 5 | 1,058
primary pancreatic ductal adenocarcinoma 5 | 1,109
spina bifida 5 | 1,074
Atopic dermatitis 4 | 952
Bipolar Disorder 4 | 666
Breast Neoplasms 4 | 445
Carcinoma, Hepatocellular 4 | 228
Down syndrome 4 | 499
Liver Cirrhosis, Experimental 4 | 769
Liver carcinoma 4 | 240
Mammary Neoplasms 4 | 425
Melanoma 4 | 711
Muscle hypotonia 4 | 571
Myocardial Ischemia 4 | 169
Neurodegenerative disease 4 | 414
Schizophrenia 4 | 1,160
Seizures 4 | 596
active Crohn's disease 4 | 922
ductal carcinoma in situ 4 | 1,745
gastric cancer 4 | 459
non primary Sjogren syndrome sicca 4 | 891
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
ulcerative colitis 4 | 1,819
Abnormality of metabolism/homeostasis 3 | 134
Alzheimer's disease 3 | 658
Animal Mammary Neoplasms 3 | 136
Anxiety 3 | 136
Attention deficit hyperactivity disorder 3 | 278
Autistic Disorder 3 | 364
Autosomal recessive predisposition 3 | 1,442
Bradykinesia 3 | 34
Dementia 3 | 175
Dysarthria 3 | 192
Hypothyroidism 3 | 122
Lissencephaly 3 | 69
Mammary Neoplasms, Animal 3 | 136
Mammary Neoplasms, Experimental 3 | 154
Neuroblastoma 3 | 80
Parkinson's disease 3 | 392
Primary biliary cirrhosis 3 | 51
Short stature 3 | 531
Skin cancer 3 | 469
acute myeloid leukemia 3 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
medulloblastoma 3 | 720
posterior fossa group A ependymoma 3 | 468
sarcoidosis 3 | 370

Tissue

Digestive Tract 60 | 17,369
Endocrine System 60 | 18,159
Liver and Pancreas 60 | 16,750
Male tissues 60 | 17,142
Skin and soft tissues 60 | 17,230
Blood and immune system 59 | 16,909
Female tissues 59 | 17,400
Respiratory system 59 | 16,393
Urinary Tract 59 | 16,678
Cardiovascular System 58 | 15,192
Nervous System 58 | 16,725

Target Family

Non-IDG 39 | 12,091
Enzyme 16 | 4,145
Epigenetic 2 | 242
Kinase 2 | 634
Transcription Factor 1 | 1,400

GO Component

cytoplasmic ribonucleoprotein ... 60 | 60
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Heterogeneous nuclear ribonucleoprotein U HNRNPU Tbio Non-IDG -2.33813 207.8 169
NF-kappa-B inhibitor zeta NFKBIZ Tbio Non-IDG -2.14151 143.2 111
Protein LSM14 homolog A LSM14A Tbio Non-IDG -1.13869 16.0 122
Cytoskeleton-associated protein 4 CKAP4 Tbio Non-IDG -1.45279 28.4 190
DNA polymerase iota POLI Tbio Enzyme -3.24008 1701.9 333
Endoribonuclease ZC3H12A ZC3H12A Tbio Enzyme -1.81028 77.8 134
ATP-dependent RNA helicase A DHX9 Tbio Enzyme -2.85807 734.3 204
ATP-dependent RNA helicase DDX3Y DDX3Y Tbio Enzyme -1.81279 65.1 167
Protein SMG5 SMG5 Tbio Non-IDG -1.02024 9.67 88
Thiosulfate:glutathione sulfurtransferase TSTD1 Tdark Enzyme 0.23 1.22 11