Development Level

Tbio 20 | 11,651
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased total body fat amoun... 2 | 207
male infertility 2 | 123
preweaning lethality, incomple... 2 | 499
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
decreased circulating choleste... 1 | 93
decreased circulating sodium l... 1 | 22
decreased fasted circulating g... 1 | 65
enlarged lymph nodes 1 | 37
impaired glucose tolerance 1 | 75
increased circulating magnesiu... 1 | 10
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased lean body mass 1 | 172
microphthalmia 1 | 26

Disease

ovarian cancer 15 | 8,520
ependymoma 14 | 4,679
osteosarcoma 13 | 7,950
atypical teratoid / rhabdoid tumor 10 | 5,112
group 3 medulloblastoma 10 | 4,104
Carcinoma 9 | 11,493
glioblastoma 9 | 5,792
medulloblastoma, large-cell 8 | 6,241
Breast cancer 7 | 3,578
malignant mesothelioma 7 | 3,232
primitive neuroectodermal tumor 7 | 3,035
psoriasis 7 | 6,694
Multiple myeloma 6 | 1,332
lung cancer 6 | 4,740
oligodendroglioma 6 | 2,850
Asphyxiating thoracic dystrophy 5 | 44
Polydactyly 5 | 107
Short Rib-Polydactyly Syndrome 5 | 13
astrocytic glioma 5 | 2,597
invasive ductal carcinoma 5 | 2,951
Jeune thoracic dystrophy 4 | 10
Kidney cancer 4 | 2,613
Pick disease 4 | 1,894
Short-rib thoracic dysplasia 3 with or without polydactyly 4 | 9
adult high grade glioma 4 | 3,801
juvenile dermatomyositis 4 | 1,187
pancreatic cancer 4 | 2,398
Astrocytoma, Pilocytic 3 | 3,081
Atopic dermatitis 3 | 952
Ciliopathy 3 | 71
Liver cancer 3 | 604
Short rib-polydactyly syndrome, Verma-Naumoff type 3 | 5
acute quadriplegic myopathy 3 | 1,158
ductal carcinoma in situ 3 | 1,745
hepatocellular carcinoma 3 | 547
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
progressive supranuclear palsy 3 | 676
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis and treatment for 6 months 3 | 409
Abnormal skeletal development 2 | 60
Abnormality of pelvic girdle bone morphology 2 | 37
Abnormality of the clavicle 2 | 14
Abnormality of the metaphyses 2 | 48
Abnormality of the ribs 2 | 32
Brachydactyly 2 | 156
Cancer 2 | 2,499
Cone-shaped epiphyses 2 | 24
Cryptorchidism 2 | 296
Ellis-Van Creveld syndrome 2 | 19
Failure to gain weight 2 | 365
Hypoplastic feet 2 | 66
Micromelia 2 | 58
Narrow thorax 2 | 53
Osteochondrodysplasias 2 | 72
Pediatric failure to thrive 2 | 365
Respiratory Insufficiency 2 | 132
Respiratory function loss 2 | 121
Short thorax 2 | 21
Situs Inversus 2 | 65
Sternal anomalies 2 | 19
Ventricular Septal Defects 2 | 119
Waldenstrons macroglobulinemia 2 | 765
acute myeloid leukemia 2 | 783
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
chronic rhinosinusitis 2 | 512
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
gastric cancer 2 | 459
nasopharyngeal carcinoma 2 | 1,058
pancreatic carcinoma 2 | 562
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Ambiguous Genitalia 1 | 24
Decreased motor NCV 1 | 22
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Exocrine pancreatic insufficiency 1 | 32
Hydrops Fetalis 1 | 21
Hypesthesia 1 | 7
Hypoplastic toenails 1 | 22
Majewski Syndrome 1 | 2
Microdontia (disorder) 1 | 59
Papillary thyroid carcinoma 1 | 43
Pulmonary Fibrosis 1 | 106
Sensenbrenner syndrome 1 | 17
Short distal phalanges 1 | 50
Short ribs 1 | 30
Thoracic dysplasia 1 | 3
Thyroid Neoplasm 1 | 37
Thyroid Neoplasms 1 | 34
Thyroid cancer, papillary 1 | 14
short-rib thoracic dysplasia 6 with or without polydactyly 1 | 2

Tissue

Blood and immune system 21 | 16,909
Cardiovascular System 21 | 15,192
Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678

Target Family

Non-IDG 21 | 12,091

GO Component

cytoplasmic dynein complex 21 | 21
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytoplasmic dynein 1 light intermediate chain 1 DYNC1LI1 Tbio Non-IDG -1.67860 45.9 100
Dynactin subunit 4 DCTN4 Tbio Non-IDG -0.85019 7.19 160
Tctex1 domain-containing protein 2 TCTEX1D2 Tbio Non-IDG -0.72065 5.33 41
Dynein light chain 1, cytoplasmic DYNLL1 Tbio Non-IDG -2.77874 581.3 185
Bcl-2-like protein 11 BCL2L11 Tbio Non-IDG -3.18092 1465.8 931
Cytoplasmic dynein 1 intermediate chain 2 DYNC1I2 Tbio Non-IDG -2.29634 178.5 104
Cytoplasmic dynein 1 intermediate chain 1 DYNC1I1 Tbio Non-IDG -0.74893 5.97 92
WD repeat-containing protein 34 WDR34 Tbio Non-IDG -0.93434 9.53 96
Sorting nexin-4 SNX4 Tbio Non-IDG -1.04850 10.1 191
WD repeat-containing protein 60 WDR60 Tbio Non-IDG -0.64761 3.98 23