Development Level

Tbio 90 | 10,625
Tchem 18 | 1,890
Tdark 15 | 7,003
Tclin 9 | 602

IMPC Term

preweaning lethality, complete... 11 | 633
abnormal behavior 4 | 226
abnormal embryo size 3 | 112
decreased body weight 2 | 174
decreased circulating fructosa... 2 | 31
decreased circulating serum al... 2 | 79
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
increased circulating HDL chol... 2 | 63
increased circulating choleste... 2 | 53
increased fasted circulating g... 2 | 68
increased total body fat amoun... 2 | 57
prenatal lethality prior to he... 2 | 64
preweaning lethality, incomple... 2 | 260
abnormal eye morphology 1 | 38
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal lens morphology 1 | 73
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal respiratory quotient 1 | 9
abnormal seminal vesicle morph... 1 | 47
abnormal sleep behavior 1 | 63
abnormal tail movements 1 | 12
absent pinna reflex 1 | 21
anophthalmia 1 | 20
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating potassiu... 1 | 17
decreased circulating total pr... 1 | 41
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
decreased total body fat amoun... 1 | 186
decreased total retina thickne... 1 | 20
dilated heart left ventricle 1 | 10
enlarged heart 1 | 111
hydrops fetalis 1 | 22
impaired glucose tolerance 1 | 52
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased cardiac stroke volum... 1 | 1
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating free fat... 1 | 17
increased circulating phosphat... 1 | 24
increased circulating triglyce... 1 | 24
increased exploration in new e... 1 | 56
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 93
increased or absent threshold ... 1 | 128
increased prepulse inhibition 1 | 21
increased respiratory quotient 1 | 12
increased sacral vertebrae num... 1 | 62
tremors 1 | 34
trunk curl 1 | 15

Disease

ovarian cancer 70 | 8,484
osteosarcoma 67 | 7,933
psoriasis 52 | 6,685
medulloblastoma, large-cell 51 | 6,234
glioblastoma 46 | 5,572
atypical teratoid / rhabdoid tumor 42 | 4,369
pilocytic astrocytoma 34 | 3,086
invasive ductal carcinoma 31 | 2,950
lung cancer 31 | 4,466
pediatric high grade glioma 29 | 2,712
Breast cancer 28 | 3,094
ependymoma 28 | 2,514
subependymal giant cell astrocytoma 28 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 27 | 2,988
malignant mesothelioma 27 | 3,162
interstitial cystitis 26 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,289
non-small cell lung cancer 25 | 2,798
oligodendroglioma 25 | 2,849
primitive neuroectodermal tumor 25 | 3,031
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,956
lung adenocarcinoma 24 | 2,713
Cancer 23 | 2,346
astrocytic glioma 22 | 2,241
lung carcinoma 22 | 2,844
pancreatic cancer 21 | 2,300
ductal carcinoma in situ 19 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,795
ulcerative colitis 19 | 2,087
Carcinoma 18 | 2,147
breast carcinoma 18 | 1,614
medulloblastoma 18 | 1,524
adult high grade glioma 17 | 2,148
primary pancreatic ductal adenocarcinoma 17 | 1,271
Pick disease 16 | 1,893
atypical teratoid/rhabdoid tumor 16 | 1,095
colon cancer 16 | 1,475
astrocytoma 15 | 1,493
group 4 medulloblastoma 15 | 1,875
cystic fibrosis 14 | 1,665
spina bifida 14 | 1,064
gastric carcinoma 13 | 832
tuberculosis 13 | 1,557
Neurodegenerative disease 11 | 383
diabetes mellitus 11 | 1,663
esophageal adenocarcinoma 11 | 737
group 3 medulloblastoma 11 | 2,254
pituitary cancer 11 | 1,972
posterior fossa group A ependymoma 11 | 1,511
posterior fossa group B ependymoma 11 | 1,530
Down syndrome 10 | 548
Multiple myeloma 10 | 1,327
Schizophrenia 10 | 501
cutaneous lupus erythematosus 10 | 1,056
nasopharyngeal carcinoma 10 | 1,056
Alzheimer's disease 9 | 644
acute quadriplegic myopathy 9 | 1,157
adrenocortical carcinoma 9 | 1,427
non primary Sjogren syndrome sicca 9 | 840
Amyotrophic Lateral Sclerosis 8 | 431
Atopic dermatitis 8 | 944
Waldenstrons macroglobulinemia 8 | 765
active Crohn's disease 8 | 918
dermatomyositis 8 | 933
juvenile dermatomyositis 8 | 1,189
sonic hedgehog group medulloblastoma 8 | 1,482
Autistic Disorder 7 | 320
Intellectual disability 7 | 573
Multiple Sclerosis 7 | 498
Parkinson's disease 7 | 364
Rheumatoid Arthritis 7 | 1,160
inflammatory breast cancer 7 | 404
mucosa-associated lymphoid tissue lymphoma 7 | 480
progressive supranuclear palsy 7 | 674
tuberculosis and treatment for 6 months 7 | 686
Duchenne muscular dystrophy 6 | 602
Glaucoma 6 | 134
Mammary Neoplasms 6 | 410
chronic rhinosinusitis 6 | 512
fibroadenoma 6 | 557
primary Sjogren syndrome 6 | 789
Acrodermatitis enteropathica 5 | 18
Dementia 5 | 129
Epilepsy 5 | 346
Lung Neoplasms 5 | 171
Neuropathy 5 | 210
Obesity 5 | 616
Polycystic Ovary Syndrome 5 | 332
Status Epilepticus 5 | 85
aldosterone-producing adenoma 5 | 664
chronic lymphosyte leukemia 5 | 232
tuberculosis and treatment for 3 months 5 | 327
urothelial carcinoma 5 | 318
Asthma 4 | 349
Cerebrovascular disease 4 | 231
Hypertension 4 | 287
IGA Glomerulonephritis 4 | 454
acute myeloid leukemia 4 | 780
nephrosclerosis 4 | 329
pancreatic carcinoma 4 | 567

Tissue

Endocrine System 132 | 18,512
Liver and Pancreas 132 | 18,136
Blood and immune system 131 | 17,995
Digestive Tract 131 | 18,473
Female tissues 131 | 18,647
Male tissues 131 | 17,969
Nervous System 131 | 18,561
Skin and soft tissues 131 | 18,115
Urinary Tract 131 | 18,444
Cardiovascular System 130 | 17,958
Respiratory system 130 | 17,484

Target Family

Non-IDG 84 | 11,971
Enzyme 24 | 4,146
Kinase 10 | 634
Transporter 7 | 473
GPCR 4 | 406
Ion Channel 3 | 341

GO Component

cytoplasmic, membrane-bounded ... 132 | 132
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-binding cassette sub-family A member 2 ABCA2 Tbio Transporter -1.41708 32.2 125
Angiogenin ANG Tbio Enzyme -2.89794 796.0 203
Serotransferrin TF Tchem Non-IDG -4.13136 13124.3 952
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.39868 2437.0 1167
Suppressor of cytokine signaling 1 SOCS1 Tbio Non-IDG -3.00271 1072.1 392
Ral-GDS-related protein RGL4 Tdark Non-IDG -0.20713 1.47 53
Fibroblast growth factor receptor 1 FGFR1 Tclin Kinase -3.07424 1194.2 1600
Neurensin-1 NRSN1 Tdark Non-IDG -1.70429 52.8 50
3-phosphoinositide-dependent protein kinase 1 PDPK1 Tchem Kinase -2.24871 191.5 579
Sodium channel protein type 8 subunit alpha SCN8A Tclin Ion Channel -2.43832 279.5 169