Development Level

Tbio 16 | 11,651
Tchem 3 | 1,388
Tdark 2 | 6,593

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
abnormal behavior 2 | 298
decreased body weight 2 | 161
decreased circulating HDL chol... 2 | 68
decreased circulating LDL chol... 2 | 38
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
increased circulating chloride... 2 | 41
increased lean body mass 2 | 172
preweaning lethality, complete... 2 | 979
abnormal allantois morphology 1 | 8
abnormal bone structure 1 | 187
abnormal chorioallantoic fusio... 1 | 8
abnormal coat appearance 1 | 31
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal retinal inner nuclear... 1 | 8
abnormal sleep behavior 1 | 70
abnormal vertebrae morphology 1 | 18
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased exploration in new e... 1 | 11
decreased glycosylated hemoglo... 1 | 1
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased mean corpuscular hem... 1 | 50
decreased mean platelet volume 1 | 25
decreased total retina thickne... 1 | 17
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hypoactivity 1 | 132
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
thin ventricular wall 1 | 24
tremors 1 | 39

Disease

Carcinoma 19 | 11,493
osteosarcoma 13 | 7,950
ovarian cancer 12 | 8,520
psoriasis 11 | 6,694
atypical teratoid / rhabdoid tumor 10 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
glioblastoma 9 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
Cancer 8 | 2,499
medulloblastoma, large-cell 8 | 6,241
Astrocytoma, Pilocytic 7 | 3,081
group 3 medulloblastoma 7 | 4,104
primitive neuroectodermal tumor 7 | 3,035
ependymoma 6 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung cancer 6 | 4,740
Hypertension 5 | 396
Liver Cirrhosis, Experimental 5 | 769
Malaria 5 | 160
diabetes mellitus 5 | 1,728
ductal carcinoma in situ 5 | 1,745
invasive ductal carcinoma 5 | 2,951
lung carcinoma 5 | 2,843
non-small cell lung cancer 5 | 2,890
pancreatic cancer 5 | 2,398
Alzheimer's disease 4 | 658
Animal Mammary Neoplasms 4 | 136
Breast cancer 4 | 3,578
Hereditary elliptocytosis 4 | 22
Kidney disease 4 | 430
Mammary Neoplasms, Animal 4 | 136
Mammary Neoplasms, Experimental 4 | 154
adrenocortical carcinoma 4 | 1,428
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
mucosa-associated lymphoid tissue lymphoma 4 | 484
oligodendroglioma 4 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
spina bifida 4 | 1,074
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Abnormality of metabolism/homeostasis 3 | 134
Anemia 3 | 365
Anemia, Hemolytic 3 | 55
Autosomal recessive predisposition 3 | 1,442
Bipolar Disorder 3 | 666
Brain Ischemia 3 | 110
Cerebrovascular disease 3 | 238
Congenital hemolytic anemia 3 | 32
Cryptorchidism 3 | 296
Dementia 3 | 175
Depressive disorder 3 | 409
Down syndrome 3 | 499
Elliptocytosis, Hereditary 3 | 9
Epilepsy 3 | 792
Esophageal Neoplasms 3 | 69
Heart disease 3 | 306
Intellectual disability 3 | 1,016
Kidney cancer 3 | 2,613
Lung Neoplasms 3 | 232
Lung disease 3 | 142
Postnatal growth retardation 3 | 57
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
Seizures 3 | 596
aldosterone-producing adenoma 3 | 665
colon cancer 3 | 1,478
group 4 medulloblastoma 3 | 1,855
pancreatic carcinoma 3 | 562
pediatric high grade glioma 3 | 1,064
ulcerative colitis 3 | 1,819
Acquired scoliosis 2 | 281
Arthritis 2 | 290
Atherosclerosis 2 | 291
Broad flat nasal bridge 2 | 236
Curvature of spine 2 | 282
Essential Hypertension 2 | 94
Eye disease 2 | 62
Failure to gain weight 2 | 365
Lissencephaly 2 | 69
Mental Depression 2 | 333
Multiple Sclerosis 2 | 540
Myocardial Ischemia 2 | 169
Nasal bridge wide 2 | 236
Pediatric failure to thrive 2 | 365
Polycystic ovary syndrome 2 | 360
Reperfusion Injury 2 | 86
Short nose 2 | 132
Small nose 2 | 132
Vascular disease 2 | 319
acute quadriplegic myopathy 2 | 1,158
astrocytoma 2 | 1,146
atypical teratoid/rhabdoid tumor 2 | 357
breast carcinoma 2 | 1,638
dermatomyositis 2 | 966
juvenile dermatomyositis 2 | 1,187
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Skin and soft tissues 21 | 17,230
Blood and immune system 20 | 16,909
Digestive Tract 20 | 17,369
Urinary Tract 20 | 16,678
Cardiovascular System 19 | 15,192
Nervous System 19 | 16,725
Respiratory system 19 | 16,393

Target Family

Non-IDG 17 | 12,091
Enzyme 2 | 4,145
Ion Channel 1 | 344
Transporter 1 | 473

GO Component

cortical cytoskeleton 21 | 21
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
F-actin-capping protein subunit alpha-3 CAPZA3 Tdark Non-IDG -0.56455 3.20 78
E-selectin SELE Tchem Non-IDG -3.44926 2672.1 919
Ezrin EZR Tbio Non-IDG -2.99865 981.3 1088
Tropomodulin-1 TMOD1 Tbio Non-IDG -1.84485 74.1 155
Erythrocyte membrane protein band 4.2 EPB42 Tbio Enzyme -0.95726 6.65 66
Dematin DMTN Tbio Non-IDG -1.73686 56.6 158
NMDA receptor synaptonuclear signaling and neuronal migration factor NSMF Tbio Non-IDG -0.74299 6.02 122
Actin, cytoplasmic 1 ACTB Tbio Non-IDG -3.52930 2830.7 1251
F-actin-capping protein subunit alpha-2 CAPZA2 Tdark Non-IDG -0.56574 3.27 128
Protein 4.1 EPB41 Tbio Non-IDG -2.85166 692.3 245