Development Level

Tbio 16 | 11,445
Tdark 5 | 6,588

IMPC Phenotype

decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal spleen morphology 1 | 55
cardiovascular system phenotyp... 1 | 36
decreased basophil cell number 1 | 16
decreased caudal vertebrae num... 1 | 53
decreased eosinophil cell numb... 1 | 24
decreased heart rate variabili... 1 | 13
edema 1 | 59
enlarged spleen 1 | 41
hydrometra 1 | 53
increased or absent threshold ... 1 | 101
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 12 | 11,493
osteosarcoma 9 | 7,950
psoriasis 9 | 6,694
Erythrokeratodermia variabilis 8 | 10
ovarian cancer 8 | 8,520
Oculodentodigital dysplasia 7 | 14
adult high grade glioma 7 | 3,801
interstitial cystitis 6 | 2,312
lung adenocarcinoma 6 | 2,716
medulloblastoma, large-cell 6 | 6,241
non-small cell lung cancer 6 | 2,890
Breast cancer 5 | 3,578
Cataract 5 | 297
Clouston syndrome 5 | 9
Nonsyndromic deafness 5 | 142
Palmoplantar keratosis 5 | 74
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
Alopecia 4 | 115
Autosomal recessive predisposition 4 | 1,442
Deafness, autosomal recessive 1A 4 | 4
Erythema 4 | 58
Flushing 4 | 60
Hyperkeratosis, generalized 4 | 14
Hypertension 4 | 396
Hypertensive disease 4 | 292
Lens Opacities 4 | 231
Sensorineural hearing loss 4 | 106
Small head 4 | 374
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
lung cancer 4 | 4,740
pancreatic cancer 4 | 2,398
primitive neuroectodermal tumor 4 | 3,035
ulcerative colitis 4 | 1,819
Autistic Disorder 3 | 364
Bart-Pumphrey syndrome 3 | 4
Cancer 3 | 2,499
Charcot-Marie-Tooth disease 3 | 62
Conductive hearing loss 3 | 123
DEAFNESS, AUTOSOMAL RECESSIVE 1A (disorder) 3 | 3
Deafness 3 | 198
Dull intelligence 3 | 645
Dystrophic fingernails 3 | 18
Enlarged vestibular aqueduct 3 | 10
Epilepsy 3 | 792
Fine hair 3 | 42
Frontal bossing 3 | 157
Infantile onset 3 | 238
Intellectual disability 3 | 1,016
Low Vision 3 | 174
Low intelligence 3 | 645
MEDNIK syndrome 3 | 8
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Myopia 3 | 176
Nail dysplasia 3 | 52
Neuropathy 3 | 261
Poor school performance 3 | 645
Schizophrenia 3 | 1,160
Sensorineural Hearing Loss (disorder) 3 | 284
Short stature 3 | 531
Skin Neoplasms 3 | 69
Sparse eyelashes 3 | 31
Sparse hair 3 | 59
Thin, sparse hair 3 | 59
Visual Impairment 3 | 174
X- linked recessive 3 | 110
breast carcinoma 3 | 1,638
diabetes mellitus 3 | 1,728
ependymoma 3 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
Abnormal blistering of the skin 2 | 54
Absence of eyebrows 2 | 31
Aplasia/Hypoplasia of the eyebrow 2 | 31
Blister of skin 2 | 54
Broad thumbs 2 | 28
Congenital deafness 2 | 185
Cortical white matter abnormalities seen on MRI 2 | 18
Dry skin 2 | 75
Dystrophia unguium 2 | 53
Enophthalmos 2 | 75
Hearing Loss, Partial 2 | 185
Leukoaraiosis 2 | 18
Peripheral Neuropathy 2 | 134
Photodysphoria 2 | 121
Photophobia 2 | 121
Sinoatrial node disease 2 | 5
Skin bulla 2 | 54
Sparse or absent eyebrows 2 | 31
Sparse/absent eyebrows 2 | 31
Sunken eyes 2 | 63
Weight decreased 2 | 103
Xerosis 2 | 75
facioscapulohumeral dystrophy 2 | 288
hearing impairment 2 | 199

Tissue

Endocrine System 20 | 18,159
Urinary Tract 19 | 16,678
Female tissues 18 | 17,400
Digestive Tract 17 | 17,369
Liver and Pancreas 17 | 16,750
Skin and soft tissues 17 | 17,230
Blood and immune system 16 | 16,909
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 14 | 16,393
Cardiovascular System 13 | 15,192

Target Family

Non-IDG 21 | 12,091

GO Component

connexin complex 21 | 21
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Gap junction delta-2 protein GJD2 Tbio Non-IDG -2.48933 326.9 192
Gap junction alpha-3 protein GJA3 Tbio Non-IDG -2.14059 135.1 171
Gap junction alpha-8 protein GJA8 Tbio Non-IDG -2.81282 660.2 196
Gap junction alpha-4 protein GJA4 Tbio Non-IDG -2.27043 180.6 231
Gap junction alpha-5 protein GJA5 Tbio Non-IDG -2.59423 377.5 194
Putative gap junction epsilon-1 protein GJE1 Tdark Non-IDG -0.53712 3.69 16
Gap junction beta-2 protein GJB2 Tbio Non-IDG -3.17642 1514.7 242
Gap junction beta-3 protein GJB3 Tbio Non-IDG -2.13572 133.9 212
Gap junction alpha-10 protein GJA10 Tdark Non-IDG 0.15 0.90 51
Gap junction beta-1 protein GJB1 Tbio Non-IDG -2.93115 861.6 295