Development Level

Tbio 6 | 11,445
Tchem 5 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal lens morphology 1 | 81
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased thermal nociceptive ... 1 | 9
preweaning lethality, incomple... 1 | 499
sclerocornea 1 | 2

Disease

atypical teratoid / rhabdoid tumor 8 | 5,112
Carcinoma 7 | 11,493
glioblastoma 7 | 5,792
medulloblastoma, large-cell 7 | 6,241
Breast cancer 6 | 3,578
ovarian cancer 6 | 8,520
psoriasis 6 | 6,694
Cancer 5 | 2,499
group 3 medulloblastoma 5 | 4,104
lung cancer 5 | 4,740
osteosarcoma 5 | 7,950
Kidney cancer 4 | 2,613
adult high grade glioma 4 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
primitive neuroectodermal tumor 4 | 3,035
Atopic dermatitis 3 | 952
CREST Syndrome 3 | 16
Endometriosis 3 | 540
Pick disease 3 | 1,894
Systemic scleroderma 3 | 60
adrenocortical carcinoma 3 | 1,428
ependymoma 3 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
Amyotrophic lateral sclerosis 2 | 451
Calcinosis 2 | 70
Dyskinesia of esophagus 2 | 10
Gastric antral vascular ectasia 2 | 10
Neuroblastoma 2 | 80
Primary biliary cirrhosis 2 | 51
Renal Cell Carcinoma 2 | 214
Retinitis pigmentosa 11 2 | 59
Waldenstrons macroglobulinemia 2 | 765
acute myeloid leukemia 2 | 783
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
ductal carcinoma in situ 2 | 1,745
nasopharyngeal carcinoma 2 | 1,058
pediatric high grade glioma 2 | 1,064
posterior fossa group A ependymoma 2 | 468
ulcerative colitis 2 | 1,819
Acquired flat foot 1 | 72
Ambiguous Genitalia 1 | 24
Arrhythmias, Cardiac 1 | 19
Autoimmune hepatitis 1 | 11
Bloom syndrome 1 | 29
Carcinoma of colon 1 | 32
Congenital hemivertebra 1 | 25
Congenital hypoplasia of kidney 1 | 32
Coxa valga 1 | 22
Coxa valga deformity 1 | 22
Decreased projection of midface 1 | 105
Drooling 1 | 27
Dysphasia 1 | 23
Dyspnea 1 | 76
Everted lower lip vermilion 1 | 54
Exotropia 1 | 35
Flatfoot 1 | 73
Full lower lip 1 | 64
Glioma 1 | 74
Growth Disorders 1 | 35
Hyperactive behavior 1 | 91
Hypoplasia of scrotum 1 | 24
Hypotrophic midface 1 | 105
Immunodeficiency with hyper-IgM type 2 1 | 3
Infantile muscular hypotonia 1 | 12
Iron-Refractory Iron Deficiency Anemia 1 | 15
Kidney Neoplasm 1 | 29
Kidney Neoplasms 1 | 37
Knee joint valgus deformity 1 | 56
Kyphoscoliosis deformity of spine 1 | 60
Male Pseudohermaphroditism 1 | 19
Mastitis 1 | 48
Measles 1 | 22
Microcytic hypochromic anemia (disorder) 1 | 10
Midface retrusion 1 | 105
Mixed connective tissue disease 1 | 16
Myelodysplastic Syndromes 1 | 26
Open mouth 1 | 45
Perimembranous ventricular septal defect 1 | 3
Peripheral Neuropathy 1 | 134
Postnatal growth retardation 1 | 57
Progressive mental retardation 1 | 37
Prominent lower lip 1 | 64
Protruding lower lip 1 | 54
Protrusion of tongue 1 | 11
Sialorrhea 1 | 28
Small midface 1 | 105
Small testicle 1 | 75
Synovial sarcoma 1 | 25
Telangiectasis 1 | 36
Vesico-Ureteral Reflux 1 | 33
X- linked recessive 1 | 110
Xeroderma pigmentosum 1 | 43
inflammatory breast cancer 1 | 286
non-small cell lung carcinoma 1 | 317

Tissue

Blood and immune system 13 | 16,909
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Skin and soft tissues 13 | 17,230
Liver and Pancreas 12 | 16,750
Respiratory system 12 | 16,393
Urinary Tract 12 | 16,678
Cardiovascular System 11 | 15,192

Target Family

Non-IDG 8 | 12,091
Kinase 3 | 634
Epigenetic 2 | 242

GO Component

condensed nuclear chromosome, ... 13 | 13
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone-lysine N-methyltransferase KMT5C KMT5C Tchem Epigenetic 1.18 0.06 46
Shugoshin 1 SGO1 Tbio Non-IDG -2.44224 279.8 148
Calcium-responsive transactivator SS18L1 Tbio Non-IDG -0.77788 6.30 92
Synaptonemal complex protein 2-like SYCP2L Tdark Non-IDG -0.43581 2.70 15
Meiosis-specific kinetochore protein MEIKIN Tdark Non-IDG 0.00000 3
Transcriptional regulator ATRX ATRX Tbio Non-IDG -2.85277 705.9 248
Major centromere autoantigen B CENPB Tbio Non-IDG -2.31291 207.8 93
Histone-lysine N-methyltransferase KMT5B KMT5B Tchem Epigenetic -1.20275 14.3 158
Histone H3-like centromeric protein A CENPA Tbio Non-IDG -2.73322 567.0 386
Aurora kinase C AURKC Tchem Kinase -2.00731 103.6 354