Development Level

Tbio 37 | 11,651
Tchem 7 | 1,388
Tdark 4 | 6,593
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 5 | 499
abnormal behavior 2 | 298
embryonic growth retardation 2 | 106
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal skin coloration 1 | 25
absent startle reflex 1 | 24
absent teeth 1 | 3
cardiovascular system phenotyp... 1 | 36
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating unsatura... 1 | 2
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
edema 1 | 59
embryonic lethality prior to o... 1 | 239
female infertility 1 | 60
hemorrhage 1 | 23
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased exploration in new e... 1 | 8
increased heart rate variabili... 1 | 7
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
tremors 1 | 39

Disease

ovarian cancer 33 | 8,520
Carcinoma 32 | 11,493
glioblastoma 31 | 5,792
medulloblastoma, large-cell 30 | 6,241
osteosarcoma 30 | 7,950
atypical teratoid / rhabdoid tumor 24 | 5,112
psoriasis 22 | 6,694
primitive neuroectodermal tumor 20 | 3,035
adult high grade glioma 19 | 3,801
ependymoma 19 | 4,679
group 3 medulloblastoma 16 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
lung cancer 16 | 4,740
Cancer 15 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
pancreatic cancer 15 | 2,398
Astrocytoma, Pilocytic 13 | 3,081
colon cancer 11 | 1,478
invasive ductal carcinoma 11 | 2,951
lung adenocarcinoma 11 | 2,716
Kidney cancer 10 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
malignant mesothelioma 10 | 3,232
oligodendroglioma 10 | 2,850
subependymal giant cell astrocytoma 10 | 2,287
Breast cancer 9 | 3,578
Multiple myeloma 9 | 1,332
interstitial cystitis 9 | 2,312
non-small cell lung cancer 9 | 2,890
ulcerative colitis 9 | 1,819
Pick disease 8 | 1,894
adrenocortical carcinoma 8 | 1,428
astrocytic glioma 8 | 2,597
breast carcinoma 8 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
pediatric high grade glioma 8 | 1,064
Schizophrenia 7 | 1,160
dermatomyositis 7 | 966
group 4 medulloblastoma 7 | 1,855
juvenile dermatomyositis 7 | 1,187
lung carcinoma 7 | 2,843
primary pancreatic ductal adenocarcinoma 7 | 1,109
acute quadriplegic myopathy 6 | 1,158
astrocytoma 6 | 1,146
ductal carcinoma in situ 6 | 1,745
esophageal adenocarcinoma 6 | 737
tuberculosis 6 | 2,010
Microcephaly 5 | 166
Waldenstrons macroglobulinemia 5 | 765
diabetes mellitus 5 | 1,728
non primary Sjogren syndrome sicca 5 | 891
progressive supranuclear palsy 5 | 676
Autosomal recessive predisposition 4 | 1,442
Down syndrome 4 | 499
Endometriosis 4 | 540
Epilepsy 4 | 792
Liver Cirrhosis, Experimental 4 | 769
Liver cancer 4 | 604
Multiple Sclerosis 4 | 540
Neoplasm Invasiveness 4 | 161
Sloping forehead 4 | 46
active Crohn's disease 4 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
cystic fibrosis 4 | 1,696
medulloblastoma 4 | 720
nasopharyngeal carcinoma 4 | 1,058
Atopic dermatitis 3 | 952
Cataract 3 | 297
Cognitive delay 3 | 608
Crohn's disease 3 | 321
Duchenne muscular dystrophy 3 | 601
Global developmental delay 3 | 608
Intellectual disability 3 | 1,016
Lens Opacities 3 | 231
Mental and motor retardation 3 | 608
Neoplasm Metastasis 3 | 168
Polycystic ovary syndrome 3 | 360
Prenatal onset 3 | 139
Renal Cell Carcinoma 3 | 214
Rheumatoid arthritis 3 | 1,191
Seizures 3 | 596
Short stature 3 | 531
Small head 3 | 374
Stomach Neoplasms 3 | 300
cutaneous lupus erythematosus 3 | 1,057
gastric cancer 3 | 459
gastric carcinoma 3 | 807
hereditary spastic paraplegia 3 | 318
non-small cell lung carcinoma 3 | 317
pancreatic carcinoma 3 | 562
spina bifida 3 | 1,074
Arthritis 2 | 290
Glaucoma 2 | 239
Mental Depression 2 | 333
acute myeloid leukemia 2 | 783
hepatocellular carcinoma 2 | 547
nephrosclerosis 2 | 333
non diabetic and post-ischemic heart failure 2 | 200
pituitary cancer 2 | 1,972
urothelial carcinoma 2 | 318

Tissue

Endocrine System 50 | 18,159
Blood and immune system 49 | 16,909
Digestive Tract 49 | 17,369
Urinary Tract 49 | 16,678
Female tissues 48 | 17,400
Nervous System 48 | 16,725
Skin and soft tissues 48 | 17,230
Liver and Pancreas 47 | 16,750
Male tissues 47 | 17,142
Respiratory system 47 | 16,393
Cardiovascular System 46 | 15,192

Target Family

Non-IDG 30 | 12,091
Enzyme 12 | 4,145
Kinase 6 | 634
Ion Channel 1 | 344
oGPCR 1 | 421

GO Component

cleavage furrow 50 | 50
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Myosin light chain kinase, smooth muscle MYLK Tchem Kinase -2.81312 694.0 219
Fibronectin type III and SPRY domain-containing protein 1 FSD1 Tbio Non-IDG -1.38197 23.9 160
Pleckstrin homology domain-containing family G member 6 PLEKHG6 Tbio Non-IDG -0.56736 4.94 109
Rab11 family-interacting protein 4 RAB11FIP4 Tbio Non-IDG -0.68187 5.48 43
Ras-related protein Rab-11A RAB11A Tbio Enzyme -2.65458 432.1 352
Protein phosphatase Slingshot homolog 1 SSH1 Tbio Enzyme -1.45823 27.6 148
Ras-related protein Ral-A RALA Tbio Enzyme -2.22188 169.9 225
5-hydroxytryptamine receptor 3A HTR3A Tclin Ion Channel -3.38661 2426.7 262
Merlin NF2 Tbio Non-IDG -3.17301 1540.0 457