Development Level

Tbio 40 | 11,651
Tchem 8 | 1,388
Tdark 3 | 6,593
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 4 | 499
cardiovascular system phenotyp... 3 | 36
decreased total body fat amoun... 3 | 207
increased circulating HDL chol... 3 | 80
abnormal behavior 2 | 298
abnormal lens morphology 2 | 81
decreased heart rate variabili... 2 | 13
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
increased vertical activity 2 | 24
thrombocytopenia 2 | 56
abnormal coat- hair morphology 1 | 19
abnormal embryo size 1 | 220
abnormal eye anterior chamber ... 1 | 9
abnormal heart morphology 1 | 162
abnormal limb bud morphology 1 | 17
abnormal nail morphology 1 | 8
abnormal pericardium morpholog... 1 | 26
abnormal retinal outer nuclear... 1 | 3
abnormal sensory capabilities-... 1 | 8
abnormal sleep behavior 1 | 70
abnormal vitreous body morphol... 1 | 10
abnormal whole-body plethysmog... 1 | 4
cataract 1 | 92
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased circulating unsatura... 1 | 2
decreased exploration in new e... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
increased blood urea nitrogen ... 1 | 48
increased circulating LDL chol... 1 | 13
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
short tibia 1 | 97
tremors 1 | 39

Disease

Carcinoma 41 | 11,493
ovarian cancer 28 | 8,520
osteosarcoma 27 | 7,950
atypical teratoid / rhabdoid tumor 25 | 5,112
medulloblastoma, large-cell 25 | 6,241
glioblastoma 24 | 5,792
lung cancer 24 | 4,740
psoriasis 24 | 6,694
ependymoma 23 | 4,679
malignant mesothelioma 19 | 3,232
Breast cancer 17 | 3,578
Kidney cancer 17 | 2,613
astrocytic glioma 17 | 2,597
invasive ductal carcinoma 16 | 2,951
Astrocytoma, Pilocytic 15 | 3,081
Pick disease 15 | 1,894
lung carcinoma 15 | 2,843
non-small cell lung cancer 15 | 2,890
oligodendroglioma 15 | 2,850
Alzheimer's disease 14 | 658
Cancer 13 | 2,499
adult high grade glioma 13 | 3,801
subependymal giant cell astrocytoma 13 | 2,287
ductal carcinoma in situ 12 | 1,745
group 3 medulloblastoma 12 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
primitive neuroectodermal tumor 12 | 3,035
ulcerative colitis 12 | 1,819
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
tuberculosis 11 | 2,010
diabetes mellitus 10 | 1,728
lung adenocarcinoma 10 | 2,716
pancreatic cancer 10 | 2,398
pituitary cancer 10 | 1,972
Autosomal recessive predisposition 9 | 1,442
group 4 medulloblastoma 9 | 1,855
Cognitive delay 8 | 608
Global developmental delay 8 | 608
Kidney disease 8 | 430
Mental and motor retardation 8 | 608
pediatric high grade glioma 8 | 1,064
spina bifida 8 | 1,074
Down syndrome 7 | 499
Intellectual disability 7 | 1,016
dermatomyositis 7 | 966
interstitial cystitis 7 | 2,312
mucosa-associated lymphoid tissue lymphoma 7 | 484
progressive supranuclear palsy 7 | 676
Muscle hypotonia 6 | 571
Obesity 6 | 678
Schizophrenia 6 | 1,160
astrocytoma 6 | 1,146
cystic fibrosis 6 | 1,696
esophageal adenocarcinoma 6 | 737
Atherosclerosis 5 | 291
Atopic dermatitis 5 | 952
Cataract 8 multiple types 5 | 33
Dull intelligence 5 | 645
Epilepsy 5 | 792
Liver cancer 5 | 604
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Neurodegenerative disease 5 | 414
Poor school performance 5 | 645
adrenocortical carcinoma 5 | 1,428
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Alzheimer Disease 4 | 83
Anemia 4 | 365
Arthritis 4 | 290
Coronary artery disease 4 | 268
Gaucher disease type 1 4 | 180
Hypertension 4 | 396
Liver Cirrhosis, Experimental 4 | 769
Parkinson's disease 4 | 392
Proteinuria 4 | 144
Seizures 4 | 596
Vascular disease 4 | 319
acute quadriplegic myopathy 4 | 1,158
fibroadenoma 4 | 559
juvenile dermatomyositis 4 | 1,187
nephrosclerosis 4 | 333
primary pancreatic ductal adenocarcinoma 4 | 1,109
Bipolar Disorder 3 | 666
Chronic Lymphocytic Leukemia 3 | 262
Depressive disorder 3 | 409
Multiple myeloma 3 | 1,332
Myocardial Ischemia 3 | 169
Rheumatoid arthritis 3 | 1,191
Waldenstrons macroglobulinemia 3 | 765
aldosterone-producing adenoma 3 | 665
chronic rhinosinusitis 3 | 512
gastric carcinoma 3 | 807
nasopharyngeal carcinoma 3 | 1,058
non diabetic and post-ischemic heart failure 3 | 200
primary Sjogren syndrome 3 | 735
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Digestive Tract 52 | 17,369
Endocrine System 52 | 18,159
Female tissues 52 | 17,400
Liver and Pancreas 52 | 16,750
Male tissues 52 | 17,142
Nervous System 52 | 16,725
Skin and soft tissues 52 | 17,230
Urinary Tract 52 | 16,678
Blood and immune system 51 | 16,909
Respiratory system 51 | 16,393
Cardiovascular System 49 | 15,192

Target Family

Non-IDG 44 | 12,091
Enzyme 3 | 4,145
Kinase 2 | 634
Epigenetic 1 | 242
GPCR 1 | 408
Transporter 1 | 473

GO Component

clathrin-coated pit 52 | 52
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epsin-1 EPN1 Tbio Non-IDG -1.52389 32.5 163
E-selectin SELE Tchem Non-IDG -3.44926 2672.1 919
Atypical chemokine receptor 3 ACKR3 Tchem GPCR -1.91187 99.0 476
Inositol polyphosphate 5-phosphatase OCRL-1 OCRL Tbio Enzyme -2.20394 172.2 226
Disabled homolog 2 DAB2 Tbio Non-IDG -2.26146 184.8 239
Protein amnionless AMN Tbio Non-IDG -1.36104 18.1 35
Unconventional myosin-VI MYO6 Tbio Non-IDG -1.72509 54.2 108
Low-density lipoprotein receptor LDLR Tchem Non-IDG -3.06808 938.9 585
Dynamin-2 DNM2 Tchem Non-IDG -2.43547 282.5 143
Beta-arrestin-1 ARRB1 Tbio Non-IDG -2.63877 418.5 490