Development Level

Tbio 13 | 11,445

IMPC Phenotype

decreased circulating serum al... 1 | 82
female infertility 1 | 60
increased or absent threshold ... 1 | 101
male infertility 1 | 123

Disease

Carcinoma 13 | 11,493
osteosarcoma 8 | 7,950
ovarian cancer 7 | 8,520
atypical teratoid / rhabdoid tumor 5 | 5,112
medulloblastoma, large-cell 5 | 6,241
ependymoma 4 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
Autosomal recessive predisposition 3 | 1,442
Cataract 8 multiple types 3 | 33
Coarse facial features 3 | 108
Epilepsy 3 | 792
Prenatal onset 3 | 139
Small head 3 | 374
Thickened facial skin with coarse facial features 3 | 108
astrocytoma 3 | 1,146
glioblastoma 3 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
primitive neuroectodermal tumor 3 | 3,035
psoriasis 3 | 6,694
Alzheimer's disease 2 | 658
Astrocytoma, Pilocytic 2 | 3,081
Babinski Reflex 2 | 100
Bulbous nasal tip 2 | 48
Bulbous nose 2 | 48
Cerebral palsy 2 | 40
Cognitive delay 2 | 608
Dilated ventricles (finding) 2 | 121
Global developmental delay 2 | 608
Hermansky-Pudlak syndrome 2 | 42
Horner's syndrome 2 | 11
Hyperreflexia 2 | 209
Hypoplasia of corpus callosum 2 | 90
Intellectual disability 2 | 1,016
Macrostomia 2 | 72
Mental and motor retardation 2 | 608
Microcephaly 2 | 166
Narrow forehead 2 | 34
Neonatal Hypotonia 2 | 64
Neurodegenerative disease 2 | 414
Pain agnosia 2 | 104
Paraplegia 2 | 74
Pick disease 2 | 1,894
Potato nose 2 | 48
Quadriplegia 2 | 20
Seizures 2 | 596
Severe mental retardation (I.Q. 20-34) 2 | 99
Short philtrum 2 | 53
Spastic Paraplegia 2 | 42
Strabismus 2 | 270
adult high grade glioma 2 | 3,801
diabetes mellitus 2 | 1,728
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
hereditary spastic paraplegia 2 | 318
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Adducted thumb 1 | 22
Atrophy of cerebellum 1 | 103
Cerebellar degeneration 1 | 103
Class III malocclusion 1 | 78
Congenital clubfoot 1 | 109
Decreased platelet count 1 | 111
Delayed speech and language development 1 | 112
Dysarthria 1 | 192
Dystonia 1 | 164
Dystonic disease 1 | 106
Gliosis 1 | 56
Globe disease 1 | 67
Hip Dislocation, Congenital 1 | 48
Hypertrophy of breast 1 | 17
Hypertrophy of lower jaw 1 | 78
Increased size of mandible 1 | 78
Infratentorial atrophy 1 | 103
Low Vision 1 | 174
Mandibular hyperplasia 1 | 78
Motor delay 1 | 147
Neutropenia 1 | 72
No development of motor milestones 1 | 147
Oculocutaneous albinism 1 | 29
Periventricular white matter abnormalities 1 | 8
Photodysphoria 1 | 121
Photophobia 1 | 121
Platelet storage pool deficiency 1 | 21
Slow progression 1 | 89
Spastic Paraplegia 47, Autosomal Recessive 1 | 1
Spastic Quadriplegia 1 | 42
Speech Delay 1 | 112
Speech impairment 1 | 112
Thrombocytopenia 1 | 197
Visual Impairment 1 | 174
Waddling gait 1 | 34
mandibular excess (physical finding) 1 | 78
sarcoidosis 1 | 370

Tissue

Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Non-IDG 13 | 12,091

GO Component

clathrin adaptor complex 13 | 13
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
AP-3 complex subunit beta-1 AP3B1 Tbio Non-IDG -1.27699 21.0 89
AP-3 complex subunit beta-2 AP3B2 Tbio Non-IDG -0.76737 5.95 100
AP-1 complex subunit mu-1 AP1M1 Tbio Non-IDG -1.22917 13.8 121
AP-3 complex subunit mu-1 AP3M1 Tbio Non-IDG 0.00000 0.83 98
ADP-ribosylation factor-binding protein GGA1 GGA1 Tbio Non-IDG -1.92140 81.7 174
ADP-ribosylation factor-binding protein GGA2 GGA2 Tbio Non-IDG -1.43055 25.6 142
AP-4 complex subunit beta-1 AP4B1 Tbio Non-IDG -0.79214 6.23 124
AP-1 complex subunit mu-2 AP1M2 Tbio Non-IDG -2.54240 341.5 68
AP-3 complex subunit mu-2 AP3M2 Tbio Non-IDG -0.66901 4.79 56
ADP-ribosylation factor-binding protein GGA3 GGA3 Tbio Non-IDG -1.64319 39.5 145