Development Level

Tbio 30 | 11,445
Tdark 8 | 6,588
Tchem 4 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased total body fat amoun... 2 | 207
abnormal behavior 1 | 298
abnormal coat- hair morphology 1 | 19
abnormal embryo size 1 | 220
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal locomotor activation 1 | 16
abnormal lung morphology 1 | 26
abnormal pancreas morphology 1 | 13
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal testis morphology 1 | 43
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased lactate dehydrogenas... 1 | 16
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
hydroencephaly 1 | 14
hydrometra 1 | 53
hyperactivity 1 | 148
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating fructosa... 1 | 13
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
long tibia 1 | 25
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

ovarian cancer 28 | 8,520
Carcinoma 26 | 11,493
osteosarcoma 22 | 7,950
glioblastoma 18 | 5,792
psoriasis 17 | 6,694
lung cancer 16 | 4,740
medulloblastoma, large-cell 16 | 6,241
atypical teratoid / rhabdoid tumor 15 | 5,112
ependymoma 14 | 4,679
Pick disease 11 | 1,894
Astrocytoma, Pilocytic 10 | 3,081
Kidney cancer 10 | 2,613
group 3 medulloblastoma 10 | 4,104
malignant mesothelioma 10 | 3,232
primitive neuroectodermal tumor 10 | 3,035
Breast cancer 9 | 3,578
adult high grade glioma 8 | 3,801
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
oligodendroglioma 7 | 2,850
Autosomal recessive predisposition 6 | 1,442
Rheumatoid arthritis 6 | 1,191
astrocytic glioma 6 | 2,597
lung adenocarcinoma 6 | 2,716
pituitary cancer 6 | 1,972
tuberculosis 6 | 2,010
Multiple myeloma 5 | 1,332
acute myeloid leukemia 5 | 783
astrocytoma 5 | 1,146
cystic fibrosis 5 | 1,696
dermatomyositis 5 | 966
diabetes mellitus 5 | 1,728
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
pancreatic cancer 5 | 2,398
pediatric high grade glioma 5 | 1,064
primary pancreatic ductal adenocarcinoma 5 | 1,109
subependymal giant cell astrocytoma 5 | 2,287
Endometrial cancer 4 | 311
colon cancer 4 | 1,478
cutaneous lupus erythematosus 4 | 1,057
hepatocellular carcinoma 4 | 547
interstitial cystitis 4 | 2,312
invasive ductal carcinoma 4 | 2,951
juvenile dermatomyositis 4 | 1,187
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
tuberculosis and treatment for 6 months 4 | 409
Amyotrophic lateral sclerosis 3 | 451
Bipolar Disorder 3 | 666
Cancer 3 | 2,499
Frontal bossing 3 | 157
Glaucoma 3 | 239
Infantile onset 3 | 238
Liver Cirrhosis, Experimental 3 | 769
active ulcerative colitis 3 | 764
acute quadriplegic myopathy 3 | 1,158
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
gastric cancer 3 | 459
non primary Sjogren syndrome sicca 3 | 891
posterior fossa group B ependymoma 3 | 416
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819
Absent reflex 2 | 92
Absent tendon reflex 2 | 92
Acquired scoliosis 2 | 281
Arthritis 2 | 290
Atopic dermatitis 2 | 952
Concave bridge of nose 2 | 195
Contracture 2 | 96
Contracture of joint 2 | 93
Curvature of spine 2 | 282
Decreased tendon reflex 2 | 122
Delayed speech and language development 2 | 112
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Down syndrome 2 | 499
Duchenne muscular dystrophy 2 | 601
Gastroesophageal reflux disease 2 | 110
Hydrophthalmos 2 | 19
Kidney disease 2 | 430
Language Delay 2 | 112
Liver cancer 2 | 604
Myopia 2 | 176
Neurodegenerative disease 2 | 414
Osteomyelitis 2 | 42
Parkinson's disease 2 | 392
Progressive disorder 2 | 142
Reflex, Deep Tendon, Absent 2 | 92
Speech Delay 2 | 112
Speech impairment 2 | 112
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
mucosa-associated lymphoid tissue lymphoma 2 | 484
pancreatic carcinoma 2 | 562
progressive supranuclear palsy 2 | 676

Tissue

Digestive Tract 42 | 17,369
Endocrine System 42 | 18,159
Urinary Tract 42 | 16,678
Blood and immune system 41 | 16,909
Cardiovascular System 41 | 15,192
Female tissues 41 | 17,400
Liver and Pancreas 41 | 16,750
Male tissues 41 | 17,142
Nervous System 41 | 16,725
Respiratory system 41 | 16,393
Skin and soft tissues 41 | 17,230

Target Family

Non-IDG 30 | 12,091
Enzyme 7 | 4,145
Kinase 3 | 634
Ion Channel 1 | 344
Transporter 1 | 473

GO Component

cis-Golgi network 42 | 42
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sec1 family domain-containing protein 1 SCFD1 Tbio Non-IDG -1.50460 33.8 170
Short transient receptor potential channel 7 TRPC7 Tchem Ion Channel -2.43775 199.8 220
Transmembrane emp24 domain-containing protein 5 TMED5 Tbio Non-IDG -0.27107 1.67 29
Golgin subfamily B member 1 GOLGB1 Tbio Non-IDG -2.75385 540.5 88
Protein angel homolog 1 ANGEL1 Tbio Non-IDG -0.17609 1.15 94
Fukutin FKTN Tbio Non-IDG -2.34994 236.9 131
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 GBF1 Tbio Non-IDG -0.60758 4.31 61
Trafficking protein particle complex subunit 6A TRAPPC6A Tbio Non-IDG -0.75693 6.26 83
Golgi SNAP receptor complex member 1 GOSR1 Tbio Non-IDG -1.32565 21.7 128
Alpha-mannosidase 2 MAN2A1 Tbio Enzyme -1.28977 18.7 111