Development Level

Tbio 32 | 11,445
Tdark 7 | 6,588
Tchem 5 | 1,598
Tclin 5 | 613

Collection

GPCR: IDG Consortium (Targets) 4 | 126
GPCR: IDG Consortium (Complete... 1 | 25
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal retina morphology 2 | 71
decreased circulating alkaline... 2 | 46
decreased grip strength 2 | 116
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal nail morphology 1 | 8
abnormal pericardium morpholog... 1 | 26
abnormal retinal inner nuclear... 1 | 8
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased respiratory quotient 1 | 16
decreased spleen weight 1 | 10
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased fasted circulating g... 1 | 76
increased heart rate variabili... 1 | 7
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
short tibia 1 | 97
thrombocytopenia 1 | 56

Disease

Carcinoma 42 | 11,493
ovarian cancer 26 | 8,520
osteosarcoma 19 | 7,950
ependymoma 18 | 4,679
Intellectual disability 17 | 1,016
atypical teratoid / rhabdoid tumor 17 | 5,112
glioblastoma 15 | 5,792
Polydactyly 14 | 107
medulloblastoma, large-cell 14 | 6,241
Autosomal recessive predisposition 12 | 1,442
Dull intelligence 12 | 645
Low intelligence 12 | 645
Mental Retardation 12 | 645
Mental deficiency 12 | 645
Poor school performance 12 | 645
oligodendroglioma 12 | 2,850
psoriasis 12 | 6,694
Obesity 11 | 678
astrocytic glioma 11 | 2,597
Astrocytoma, Pilocytic 10 | 3,081
Kidney cancer 10 | 2,613
adult high grade glioma 10 | 3,801
lung cancer 10 | 4,740
primitive neuroectodermal tumor 10 | 3,035
Pick disease 9 | 1,894
group 3 medulloblastoma 9 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
malignant mesothelioma 9 | 3,232
Bardet-Biedl syndrome 8 | 51
Bardet-Biedl syndrome 1 8 | 22
Breast cancer 8 | 3,578
Cone dystrophy 8 | 71
Congenital hypoplasia of penis 8 | 176
Hypertensive disease 8 | 292
Nystagmus 8 | 317
Retinitis Pigmentosa 8 | 226
Short stature 8 | 531
interstitial cystitis 8 | 2,312
invasive ductal carcinoma 8 | 2,951
lung carcinoma 8 | 2,843
non-small cell lung cancer 8 | 2,890
Ciliopathy 7 | 71
Electroretinogram abnormal 7 | 95
Hypogonadism 7 | 173
Nephronophthisis 7 | 80
Fundus dystrophy 6 | 83
Joubert syndrome 6 | 66
Meckel syndrome 6 | 46
Ulnar polydactyly of fingers 6 | 47
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
pituitary cancer 6 | 1,972
Asphyxiating thoracic dystrophy 5 | 44
Brachydactyly 5 | 156
Broad flat nasal bridge 5 | 236
Cataract 5 | 297
Cognitive delay 5 | 608
Congenital hypoplasia of ovary 5 | 30
Gastrointestinal Stromal Tumors 5 | 48
Global developmental delay 5 | 608
Hypoplastic ovary 5 | 30
Increase in blood pressure 5 | 119
Lens Opacities 5 | 231
Mental and motor retardation 5 | 608
Multicystic Dysplastic Kidney 5 | 52
Nasal bridge wide 5 | 236
Polydactyly of toes 5 | 12
Schizophrenia 5 | 1,160
Sensorineural Hearing Loss (disorder) 5 | 284
Strabismus 5 | 270
diabetes mellitus 5 | 1,728
lung adenocarcinoma 5 | 2,716
pancreatic cancer 5 | 2,398
spina bifida 5 | 1,074
subependymal giant cell astrocytoma 5 | 2,287
Autosomal dominant polycystic kidney disease 4 | 31
Autosomal recessive polycystic kidney disease 4 | 41
Bipolar Disorder 4 | 666
Endometriosis 4 | 540
Glaucoma 4 | 239
Hypertension 4 | 396
Kidney disease 4 | 430
Orbital separation excessive 4 | 244
Retinal Degeneration 4 | 106
Seizures 4 | 596
chronic rhinosinusitis 4 | 512
medulloblastoma 4 | 720
pediatric high grade glioma 4 | 1,064
posterior fossa group B ependymoma 4 | 416
progressive supranuclear palsy 4 | 676
Attention deficit hyperactivity disorder 3 | 278
Cancer 3 | 2,499
Depressive disorder 3 | 409
Multiple myeloma 3 | 1,332
astrocytoma 3 | 1,146
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
nasopharyngeal carcinoma 3 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Endocrine System 45 | 18,159
Nervous System 45 | 16,725
Digestive Tract 44 | 17,369
Female tissues 44 | 17,400
Male tissues 44 | 17,142
Liver and Pancreas 43 | 16,750
Skin and soft tissues 43 | 17,230
Respiratory system 42 | 16,393
Blood and immune system 41 | 16,909
Urinary Tract 41 | 16,678
Cardiovascular System 35 | 15,192

Target Family

Non-IDG 28 | 12,091
GPCR 11 | 408
Ion Channel 7 | 344
Enzyme 2 | 4,145
Kinase 1 | 634

GO Component

ciliary membrane 49 | 49
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hedgehog-interacting protein HHIP Tbio Non-IDG -1.83526 65.4 193
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Transmembrane protein 17 TMEM17 Tbio Non-IDG 0.61 0.56 52
G-protein coupled receptor 157 GPR157 Tdark GPCR -0.04139 1.14 111
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Thrombospondin-type laminin G domain and EAR repeat-containing protein TSPEAR Tbio Non-IDG -0.50708 4.32 75
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
Bardet-Biedl syndrome 2 protein BBS2 Tbio Non-IDG -2.84516 693.9 69
Taste receptor type 2 member 4 TAS2R4 Tbio GPCR -1.29219 17.6 27
Polycystin-1 PKD1 Tbio Non-IDG -2.60276 379.9 123