Development Level

Tbio 21 | 11,445
Tchem 5 | 1,598
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Comple... 2 | 37
Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

increased circulating chloride... 2 | 41
preweaning lethality, complete... 2 | 979
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal humerus morphology 1 | 11
abnormal limb bud morphology 1 | 17
abnormal liver size 1 | 5
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal stomach morphology 1 | 10
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating glycerol... 1 | 9
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134
long tibia 1 | 25
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34

Disease

Carcinoma 21 | 11,493
osteosarcoma 15 | 7,950
ovarian cancer 14 | 8,520
ependymoma 11 | 4,679
psoriasis 11 | 6,694
Polydactyly 9 | 107
atypical teratoid / rhabdoid tumor 8 | 5,112
group 3 medulloblastoma 8 | 4,104
malignant mesothelioma 8 | 3,232
Ciliopathy 7 | 71
Carney complex 6 | 25
Gastrointestinal Stromal Tumors 6 | 48
Short stature 6 | 531
glioblastoma 6 | 5,792
lung cancer 6 | 4,740
medulloblastoma, large-cell 6 | 6,241
pancreatic cancer 6 | 2,398
Autosomal recessive predisposition 5 | 1,442
Brachydactyly 5 | 156
Cancer 5 | 2,499
Cleft Lip 5 | 141
Cryptorchidism 5 | 296
Hydrocephalus 5 | 152
Kidney cancer 5 | 2,613
Nephronophthisis 5 | 80
adult high grade glioma 5 | 3,801
astrocytic glioma 5 | 2,597
lung carcinoma 5 | 2,843
Asphyxiating thoracic dystrophy 4 | 44
Astrocytoma, Pilocytic 4 | 3,081
Broad flat nasal bridge 4 | 236
Concave bridge of nose 4 | 195
Congenital hypoplasia of penis 4 | 176
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Frontal bossing 4 | 157
Holoprosencephaly 4 | 56
Nasal bridge wide 4 | 236
Nevoid basal cell carcinoma syndrome 4 | 16
Primary pigmented nodular adrenocortical disease 4 | 13
chronic rhinosinusitis 4 | 512
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
primitive neuroectodermal tumor 4 | 3,035
Abnormally small eyeball 3 | 97
Acute Promyelocytic Leukemia 3 | 40
Amyotrophic lateral sclerosis 3 | 451
Anteverted nostril 3 | 191
Bardet-Biedl syndrome 3 | 51
Big calvaria 3 | 147
Breast cancer 3 | 3,578
Cognitive delay 3 | 608
Congenital Epicanthus 3 | 177
Curvature of spine 3 | 282
Decreased projection of midface 3 | 105
Decreased size of eyeball 3 | 97
Depressive disorder 3 | 409
Fatigue 3 | 182
Generalized osteopenia 3 | 99
Global developmental delay 3 | 608
Highly variable severity 3 | 157
Hypertensive disease 3 | 292
Hypotrophic malar bone 3 | 129
Hypotrophic midface 3 | 105
Increase in blood pressure 3 | 119
Increased head circumference 3 | 147
Increased size of cranium 3 | 147
Increased size of skull 3 | 147
Isolated somatotropin deficiency 3 | 30
Leukemia, Promyelocytic, Acute 3 | 36
Malar flattening 3 | 129
Mental and motor retardation 3 | 608
Micromelia 3 | 58
Microphthalmos 3 | 100
Midface retrusion 3 | 105
Obesity 3 | 678
Orbital separation excessive 3 | 244
Osteopenia 3 | 99
Osteoporosis 3 | 363
POLYDACTYLY, POSTAXIAL 3 | 13
Sensenbrenner syndrome 3 | 17
Small midface 3 | 105
Strabismus 3 | 270
Ulnar polydactyly of fingers 3 | 47
Variable expressivity 3 | 157
active Crohn's disease 3 | 922
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
medulloblastoma 3 | 720
nasopharyngeal carcinoma 3 | 1,058
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
posterior fossa group B ependymoma 3 | 416
primary pancreatic ductal adenocarcinoma 3 | 1,109
ulcerative colitis 3 | 1,819
Eye Abnormalities 2 | 35
Long narrow head 2 | 75
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Penile hypospadias 2 | 106
Skeletal muscle atrophy 2 | 139
Turridolichocephaly 2 | 75

Tissue

Endocrine System 27 | 18,159
Male tissues 27 | 17,142
Blood and immune system 26 | 16,909
Cardiovascular System 26 | 15,192
Digestive Tract 26 | 17,369
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230
Urinary Tract 26 | 16,678

Target Family

Non-IDG 12 | 12,091
Kinase 6 | 634
Enzyme 5 | 4,145
Transcription Factor 4 | 1,400

GO Component

ciliary base 27 | 27
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
WD repeat-containing protein 60 WDR60 Tbio Non-IDG -0.64761 3.98 23
Protein C8orf37 C8orf37 Tbio Non-IDG -2.10097 123.4 32
Intraflagellar transport protein 52 homolog IFT52 Tbio Non-IDG -1.09507 12.7 13
Ras-related protein Rab-8A RAB8A Tbio Enzyme -2.22872 157.9 190
Serine/threonine-protein kinase ICK ICK Tchem Kinase -2.63650 422.2 179
Centrosomal protein of 126 kDa CEP126 Tdark Non-IDG -0.32736 2.12 15
TRAF3-interacting protein 1 TRAF3IP1 Tbio Non-IDG -0.90740 11.2 169
Serine/threonine-protein kinase Nek8 NEK8 Tbio Kinase -1.71536 50.9 225
Protein FAM92A FAM92A Tbio Non-IDG -0.79005 6.14 92
Suppressor of fused homolog SUFU Tbio Non-IDG -2.33544 208.6 168