Development Level

Tbio 85 | 11,445
Tdark 13 | 6,588
Tchem 7 | 1,598

Collection

Kinase: IDG Consortium (Target... 3 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 12 | 979
preweaning lethality, incomple... 5 | 499
abnormal behavior 4 | 298
male infertility 4 | 123
embryonic lethality prior to t... 3 | 278
female infertility 3 | 60
hypoactivity 3 | 132
impaired glucose tolerance 3 | 75
increased circulating alkaline... 3 | 122
increased fasted circulating g... 3 | 76
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating glucose ... 2 | 126
decreased grip strength 2 | 116
increased lean body mass 2 | 172
increased lymphocyte cell numb... 2 | 32
increased total body fat amoun... 2 | 134
prenatal lethality prior to he... 2 | 87
abnormal behavioral response t... 1 | 66
abnormal brain morphology 1 | 13
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal humerus morphology 1 | 11
abnormal nail morphology 1 | 8
abnormal pancreas morphology 1 | 13
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal startle reflex 1 | 15
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
convulsive seizures 1 | 13
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating glycerol... 1 | 16
decreased circulating insulin ... 1 | 76
decreased coping response 1 | 8
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased neutrophil cell numb... 1 | 42
decreased respiratory quotient 1 | 16
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
hydroencephaly 1 | 14
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating glycerol... 1 | 9
increased circulating iron lev... 1 | 30
increased grip strength 1 | 41
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
long tibia 1 | 25
persistence of hyaloid vascula... 1 | 33
short tibia 1 | 97
shortened RR interval 1 | 17
thrombocytopenia 1 | 56

Disease

Carcinoma 76 | 11,493
ovarian cancer 56 | 8,520
osteosarcoma 47 | 7,950
ependymoma 39 | 4,679
medulloblastoma, large-cell 38 | 6,241
atypical teratoid / rhabdoid tumor 31 | 5,112
lung cancer 31 | 4,740
psoriasis 31 | 6,694
glioblastoma 30 | 5,792
Kidney cancer 27 | 2,613
Polydactyly 27 | 107
Intellectual disability 26 | 1,016
group 3 medulloblastoma 26 | 4,104
Ciliopathy 24 | 71
Breast cancer 23 | 3,578
Autosomal recessive predisposition 22 | 1,442
adult high grade glioma 22 | 3,801
Retinitis Pigmentosa 21 | 226
Obesity 20 | 678
Pick disease 20 | 1,894
chronic rhinosinusitis 20 | 512
Dull intelligence 19 | 645
Low intelligence 19 | 645
Mental Retardation 19 | 645
Mental deficiency 19 | 645
Poor school performance 19 | 645
Nystagmus 18 | 317
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
malignant mesothelioma 18 | 3,232
Nephronophthisis 17 | 80
primitive neuroectodermal tumor 17 | 3,035
Bardet-Biedl syndrome 16 | 51
Congenital hypoplasia of penis 16 | 176
Joubert syndrome 15 | 66
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
lung carcinoma 15 | 2,843
non-small cell lung cancer 15 | 2,890
Electroretinogram abnormal 14 | 95
astrocytic glioma 14 | 2,597
invasive ductal carcinoma 14 | 2,951
Astrocytoma, Pilocytic 13 | 3,081
Hypogonadism 13 | 173
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
oligodendroglioma 13 | 2,850
Asphyxiating thoracic dystrophy 12 | 44
Cataract 12 | 297
Cerebellar Ataxia 12 | 304
Cognitive delay 12 | 608
Fundus dystrophy 12 | 83
Global developmental delay 12 | 608
Lens Opacities 12 | 231
Mental and motor retardation 12 | 608
Optic Atrophy 12 | 242
lung adenocarcinoma 12 | 2,716
Brachydactyly 11 | 156
Broad flat nasal bridge 11 | 236
Cone dystrophy 11 | 71
Nasal bridge wide 11 | 236
Retinal Degeneration 11 | 106
breast carcinoma 11 | 1,638
Abnormality of retinal pigmentation 10 | 111
Anteverted nostril 10 | 191
Multicystic Dysplastic Kidney 10 | 52
Retinal pigment epithelial abnormality 10 | 111
Short stature 10 | 531
Ulnar polydactyly of fingers 10 | 47
diabetes mellitus 10 | 1,728
nasopharyngeal carcinoma 10 | 1,058
tuberculosis 10 | 2,010
Bardet-Biedl syndrome 1 9 | 22
Cleft Palate 9 | 271
Glaucoma 9 | 239
Hyperinsulinism 9 | 133
Hypertensive disease 9 | 292
Increase in blood pressure 9 | 119
Photodysphoria 9 | 121
Photophobia 9 | 121
Small head 9 | 374
ductal carcinoma in situ 9 | 1,745
pancreatic cancer 9 | 2,398
Abnormality of the retinal vasculature 8 | 59
Atypical scarring of skin 8 | 62
Blind Vision 8 | 111
Blindness, Legal 8 | 110
Cancer 8 | 2,499
Conductive hearing loss 8 | 123
Congenital anomaly of testis 8 | 52
Cryptorchidism 8 | 296
Keratoconus 8 | 113
Meckel syndrome 8 | 46
Night blindness, progressive 8 | 51
Ophthalmoplegia 8 | 106
Senior-Loken syndrome 8 | 22
Sensorineural Hearing Loss (disorder) 8 | 284
Uranostaphyloschisis 8 | 167
cone-rod dystrophy 8 | 59
interstitial cystitis 8 | 2,312
pituitary cancer 8 | 1,972
Hydrocephalus 7 | 152
Micrognathism 7 | 275

Tissue

Endocrine System 105 | 18,159
Male tissues 104 | 17,142
Female tissues 103 | 17,400
Skin and soft tissues 103 | 17,230
Urinary Tract 103 | 16,678
Respiratory system 102 | 16,393
Digestive Tract 101 | 17,369
Liver and Pancreas 101 | 16,750
Nervous System 101 | 16,725
Blood and immune system 100 | 16,909
Cardiovascular System 97 | 15,192

Target Family

Non-IDG 85 | 12,091
Enzyme 12 | 4,145
Kinase 6 | 634
Epigenetic 1 | 242
Ion Channel 1 | 344

GO Component

ciliary basal body 105 | 105
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Growth arrest-specific protein 8 GAS8 Tbio Non-IDG -1.20822 17.3 102
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Rotatin RTTN Tbio Non-IDG -0.87856 9.51 13
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
TOG array regulator of axonemal microtubules protein 1 TOGARAM1 Tdark Non-IDG -0.23045 1.13 9
Disheveled-associated activator of morphogenesis 1 DAAM1 Tbio Non-IDG -1.45166 30.8 269
Centrosomal protein of 290 kDa CEP290 Tbio Non-IDG -2.03755 107.9 152
Bardet-Biedl syndrome 2 protein BBS2 Tbio Non-IDG -2.84516 693.9 69
B9 domain-containing protein 1 B9D1 Tdark Non-IDG -0.61316 3.72 43