Development Level

Tbio 42 | 10,625
Tchem 8 | 1,890
Tdark 3 | 7,003
Tclin 1 | 602

IMPC Term

preweaning lethality, complete... 4 | 633
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased mean corpuscular hem... 2 | 34
female infertility 2 | 34
increased bone mineral content 2 | 92
increased bone mineral density 2 | 52
increased circulating HDL chol... 2 | 63
increased circulating chloride... 2 | 43
increased lean body mass 2 | 107
increased sacral vertebrae num... 2 | 62
male infertility 2 | 62
abnormal behavior 1 | 226
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal coat/hair pigmentatio... 1 | 54
abnormal craniofacial morpholo... 1 | 12
abnormal embryo size 1 | 112
abnormal gait 1 | 51
abnormal rib morphology 1 | 28
decreased IgG1 level 1 | 4
decreased Ly6C-positive mature... 1 | 4
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased granulocyte number 1 | 8
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased total body fat amoun... 1 | 186
embryonic growth retardation 1 | 28
embryonic lethality prior to t... 1 | 187
increased blood urea nitrogen ... 1 | 44
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased or absent threshold ... 1 | 128
increased rib number 1 | 41
increased thermal nociceptive ... 1 | 9
increased thoracic vertebrae n... 1 | 8
increased total body fat amoun... 1 | 57
polydactyly 1 | 22
preweaning lethality, incomple... 1 | 260
shortened PQ interval 1 | 6
shortened PR interval 1 | 5
vertebral fusion 1 | 23

Disease

medulloblastoma, large-cell 37 | 6,234
ovarian cancer 37 | 8,484
psoriasis 31 | 6,685
glioblastoma 30 | 5,572
primitive neuroectodermal tumor 29 | 3,031
osteosarcoma 27 | 7,933
pediatric high grade glioma 27 | 2,712
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,289
lung cancer 24 | 4,466
Breast cancer 23 | 3,094
non-small cell lung cancer 23 | 2,798
group 3 medulloblastoma 22 | 2,254
lung adenocarcinoma 21 | 2,713
malignant mesothelioma 21 | 3,162
adrenocortical carcinoma 20 | 1,427
atypical teratoid / rhabdoid tumor 20 | 4,369
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,988
invasive ductal carcinoma 19 | 2,950
Cancer 18 | 2,346
ductal carcinoma in situ 16 | 1,745
posterior fossa group A ependymoma 14 | 1,511
Endometriosis 13 | 535
nasopharyngeal carcinoma 13 | 1,056
Atopic dermatitis 12 | 944
Carcinoma 12 | 2,147
atypical teratoid/rhabdoid tumor 12 | 1,095
oligodendroglioma 12 | 2,849
colon cancer 10 | 1,475
pancreatic cancer 10 | 2,300
Rheumatoid Arthritis 9 | 1,160
Waldenstrons macroglobulinemia 9 | 765
breast carcinoma 9 | 1,614
dermatomyositis 9 | 933
pilocytic astrocytoma 9 | 3,086
IGA Glomerulonephritis 8 | 454
Intellectual disability 8 | 573
ulcerative colitis 8 | 2,087
astrocytic glioma 7 | 2,241
sonic hedgehog group medulloblastoma 7 | 1,482
Cornelia de Lange syndrome 6 | 21
Multiple myeloma 6 | 1,327
ependymoma 6 | 2,514
inflammatory breast cancer 6 | 404
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
acute quadriplegic myopathy 5 | 1,157
aldosterone-producing adenoma 5 | 664
interstitial cystitis 5 | 2,299
tuberculosis and treatment for 6 months 5 | 686
Down syndrome 4 | 548
Infertility 4 | 163
Mammary Neoplasms 4 | 410
Myeloid Leukemia 4 | 19
Pick disease 4 | 1,893
Roberts syndrome 4 | 16
adult high grade glioma 4 | 2,148
astrocytoma 4 | 1,493
diabetes mellitus 4 | 1,663
group 4 medulloblastoma 4 | 1,875
non primary Sjogren syndrome sicca 4 | 840
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
subependymal giant cell astrocytoma 4 | 2,287
Bladder Neoplasm 3 | 109
KBG syndrome 3 | 8
Leukemia, Megakaryoblastic, of Down Syndrome 3 | 9
Male infertility 3 | 170
Premature ovarian failure 3 | 64
active Crohn's disease 3 | 918
gastric carcinoma 3 | 832
juvenile dermatomyositis 3 | 1,189
medulloblastoma 3 | 1,524
spina bifida 3 | 1,064
Acquired metabolic disease 2 | 267
Adenocarcinoma 2 | 115
Autistic Disorder 2 | 320
CREST syndrome 2 | 10
Calcinosis 2 | 62
Colonic Neoplasms 2 | 126
Colorectal Neoplasms 2 | 217
Craniofacial Abnormalities 2 | 147
Endometrial cancer 2 | 25
Facies 2 | 8
Gastric antral vascular ectasia 2 | 11
Growth Deficiency and Mental Retardation with Facial Dysmorphism 2 | 3
Lung Neoplasms 2 | 171
Lymphoma, T-Cell, Cutaneous 2 | 21
Pancreatic Neoplasm 2 | 79
SC phocomelia syndrome 2 | 4
Seckel syndrome 2 | 34
Stomach Neoplasms 2 | 282
Systemic scleroderma 2 | 66
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
non-small cell lung carcinoma 2 | 413
ovarian neoplasm 2 | 97
periodontitis 2 | 269
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 789
primary pancreatic ductal adenocarcinoma 2 | 1,271
Laryngotracheitis 1 | 10
Primary ciliary dyskinesia 1 | 73
Testicular Germ Cell Tumor 1 | 22

Tissue

Blood and immune system 54 | 17,995
Cardiovascular System 54 | 17,958
Digestive Tract 54 | 18,473
Endocrine System 54 | 18,512
Female tissues 54 | 18,647
Liver and Pancreas 54 | 18,136
Male tissues 54 | 17,969
Nervous System 54 | 18,561
Respiratory system 54 | 17,484
Skin and soft tissues 54 | 18,115
Urinary Tract 54 | 18,444

Target Family

Non-IDG 40 | 11,971
Enzyme 7 | 4,146
Epigenetic 6 | 242
Transcription Factor 1 | 1,400

GO Component

chromosome, centromeric region 54 | 54
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kinetochore protein Nuf2 NUF2 Tbio Non-IDG -1.66072 48.8 98
Centromere protein F CENPF Tbio Non-IDG -1.98596 103.0 180
Histone H3-like centromeric protein A CENPA Tbio Non-IDG -2.68837 532.8 347
Neuroguidin NGDN Tbio Non-IDG -2.18414 121.6 78
Protein Mis18-alpha MIS18A Tdark Non-IDG -2.10690 101.0 41
Structural maintenance of chromosomes protein 1B SMC1B Tbio Non-IDG -1.26509 19.6 93
Shugoshin 2 SGO2 Tbio Non-IDG -1.30220 21.1 82
Shugoshin 1 SGO1 Tbio Non-IDG -2.38169 259.7 124
Synaptonemal complex protein 3 SYCP3 Tbio Non-IDG -2.15623 144.9 251
Proliferation marker protein Ki-67 MKI67 Tbio Non-IDG -2.46535 260.9 996