Development Level

Tbio 45 | 11,651
Tchem 6 | 1,388
Tdark 2 | 6,593
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 4 | 499
decreased bone mineral content 3 | 151
abnormal behavior 2 | 298
cataract 2 | 92
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased heart left ventricle... 2 | 28
decreased lean body mass 2 | 135
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased circulating HDL chol... 2 | 80
increased circulating chloride... 2 | 41
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal lens morphology 1 | 81
abnormal rib morphology 1 | 10
abnormal skin coloration 1 | 25
decreased IgG1 level 1 | 8
decreased blood urea nitrogen ... 1 | 51
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating triglyce... 1 | 79
decreased mean corpuscular hem... 1 | 50
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
female infertility 1 | 60
hydrometra 1 | 53
increased blood urea nitrogen ... 1 | 48
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
male infertility 1 | 123
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
vertebral fusion 1 | 23

Disease

Carcinoma 39 | 11,493
medulloblastoma, large-cell 37 | 6,241
ovarian cancer 37 | 8,520
group 3 medulloblastoma 32 | 4,104
psoriasis 31 | 6,694
atypical teratoid / rhabdoid tumor 30 | 5,112
glioblastoma 30 | 5,792
primitive neuroectodermal tumor 29 | 3,035
Breast cancer 28 | 3,578
osteosarcoma 27 | 7,950
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,291
lung cancer 25 | 4,740
adult high grade glioma 23 | 3,801
non-small cell lung cancer 23 | 2,890
lung adenocarcinoma 21 | 2,716
malignant mesothelioma 21 | 3,232
Cancer 20 | 2,499
adrenocortical carcinoma 20 | 1,428
ependymoma 19 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
invasive ductal carcinoma 19 | 2,951
ductal carcinoma in situ 16 | 1,745
Endometriosis 14 | 540
Kidney cancer 14 | 2,613
nasopharyngeal carcinoma 13 | 1,058
Atopic dermatitis 12 | 952
oligodendroglioma 12 | 2,850
Intellectual disability 11 | 1,016
colon cancer 10 | 1,478
pancreatic cancer 10 | 2,398
Astrocytoma, Pilocytic 9 | 3,081
Waldenstrons macroglobulinemia 9 | 765
breast carcinoma 9 | 1,638
dermatomyositis 9 | 966
Rheumatoid arthritis 8 | 1,191
pediatric high grade glioma 8 | 1,064
ulcerative colitis 8 | 1,819
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Hypoplastic mandible condyle 7 | 275
Mandibular hypoplasia 7 | 275
Mental and motor retardation 7 | 608
Micrognathism 7 | 275
Short stature 7 | 531
astrocytic glioma 7 | 2,597
Cornelia de Lange syndrome 6 | 21
Dull intelligence 6 | 645
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Multiple myeloma 6 | 1,332
Poor school performance 6 | 645
Small head 6 | 374
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
Autosomal recessive predisposition 5 | 1,442
Cryptorchidism 5 | 296
Delayed bone age 5 | 136
Endometrial cancer 5 | 311
Fetal Growth Retardation 5 | 189
Hypoplastic feet 5 | 66
Infant, Small for Gestational Age 5 | 176
Intrauterine retardation 5 | 176
Small hand 5 | 36
Thin lips 5 | 49
acute quadriplegic myopathy 5 | 1,158
aldosterone-producing adenoma 5 | 665
interstitial cystitis 5 | 2,312
tuberculosis and treatment for 6 months 5 | 409
Anteverted nostril 4 | 191
Anxiety 4 | 136
Anxiety disease 4 | 113
Attention deficit hyperactivity disorder 4 | 278
Bilateral fifth finger clinodactyly 4 | 110
Breast Neoplasms 4 | 445
Concave bridge of nose 4 | 195
Curvature of little finger 4 | 110
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Failure to gain weight 4 | 365
Gastroesophageal reflux disease 4 | 110
Heartburn 4 | 78
Infertility 4 | 188
Leukemia, Myeloid 4 | 18
Low-set, posteriorly rotated ears 4 | 110
Mammary Neoplasms 4 | 425
Myeloid Leukemia 4 | 19
Obsessive compulsive behavior 4 | 25
Pediatric failure to thrive 4 | 365
Pick disease 4 | 1,894
Roberts syndrome 4 | 15
Speech Disorders 4 | 58
astrocytoma 4 | 1,146
diabetes mellitus 4 | 1,728
group 4 medulloblastoma 4 | 1,855
non primary Sjogren syndrome sicca 4 | 891
obsessive-compulsive disorder 4 | 61
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
subependymal giant cell astrocytoma 4 | 2,287
Epilepsy 3 | 792
Micromelia 3 | 58

Tissue

Endocrine System 54 | 18,159
Female tissues 54 | 17,400
Skin and soft tissues 54 | 17,230
Blood and immune system 53 | 16,909
Digestive Tract 53 | 17,369
Male tissues 53 | 17,142
Liver and Pancreas 52 | 16,750
Respiratory system 52 | 16,393
Urinary Tract 52 | 16,678
Nervous System 50 | 16,725
Cardiovascular System 48 | 15,192

Target Family

Non-IDG 40 | 12,091
Enzyme 7 | 4,145
Epigenetic 6 | 242
Transcription Factor 1 | 1,400

GO Component

chromosome, centromeric region 54 | 54
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Chromobox protein homolog 3 CBX3 Tbio Epigenetic -2.00023 90.5 366
DNA (cytosine-5)-methyltransferase 3A DNMT3A Tclin Epigenetic -2.91291 722.8 693
Histone H3-like centromeric protein A CENPA Tbio Non-IDG -2.73322 567.0 386
Protein Mis18-alpha MIS18A Tbio Non-IDG -2.14017 104.5 47
Sister chromatid cohesion protein DCC1 DSCC1 Tbio Non-IDG -1.10259 11.9 144
Borealin CDCA8 Tbio Non-IDG -1.60291 37.6 299
Protein Mis18-beta OIP5 Tbio Non-IDG -1.25737 17.7 65
Histone-lysine N-methyltransferase SUV39H1 SUV39H1 Tchem Epigenetic -2.27556 174.3 306
Synaptonemal complex protein 3 SYCP3 Tbio Non-IDG -2.20845 154.4 255
Holliday junction recognition protein HJURP Tbio Non-IDG -1.45205 24.7 91