Development Level

Tbio 65 | 11,445
Tchem 14 | 1,598
Tdark 3 | 6,588
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, incomple... 7 | 499
preweaning lethality, complete... 6 | 979
abnormal embryo size 3 | 220
decreased total body fat amoun... 3 | 207
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal heart morphology 2 | 162
abnormal lens morphology 2 | 81
cardiovascular system phenotyp... 2 | 36
cataract 2 | 92
decreased body weight 2 | 161
decreased lean body mass 2 | 135
embryonic lethality prior to o... 2 | 239
impaired glucose tolerance 2 | 75
increased startle reflex 2 | 112
vertebral transformation 2 | 12
abnormal behavioral response t... 1 | 66
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal liver morphology 1 | 17
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
absent pinna reflex 1 | 23
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged uterus 1 | 11
female infertility 1 | 60
hydrometra 1 | 53
hyperactivity 1 | 148
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
male infertility 1 | 123
microphthalmia 1 | 26
mydriasis 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56
vertebral fusion 1 | 23

Disease

ovarian cancer 59 | 8,520
Carcinoma 58 | 11,493
osteosarcoma 45 | 7,950
medulloblastoma, large-cell 43 | 6,241
glioblastoma 42 | 5,792
lung cancer 38 | 4,740
psoriasis 34 | 6,694
atypical teratoid / rhabdoid tumor 32 | 5,112
group 3 medulloblastoma 30 | 4,104
primitive neuroectodermal tumor 30 | 3,035
Cancer 29 | 2,499
ependymoma 28 | 4,679
Breast cancer 26 | 3,578
malignant mesothelioma 26 | 3,232
oligodendroglioma 24 | 2,850
Kidney cancer 22 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
non-small cell lung cancer 21 | 2,890
adult high grade glioma 19 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
Multiple myeloma 16 | 1,332
adrenocortical carcinoma 16 | 1,428
astrocytic glioma 16 | 2,597
lung adenocarcinoma 16 | 2,716
nasopharyngeal carcinoma 14 | 1,058
Astrocytoma, Pilocytic 13 | 3,081
Waldenstrons macroglobulinemia 13 | 765
group 4 medulloblastoma 13 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
invasive ductal carcinoma 13 | 2,951
pediatric high grade glioma 13 | 1,064
subependymal giant cell astrocytoma 13 | 2,287
Rheumatoid arthritis 12 | 1,191
astrocytoma 12 | 1,146
colon cancer 12 | 1,478
Intellectual disability 11 | 1,016
diabetes mellitus 11 | 1,728
breast carcinoma 10 | 1,638
Epilepsy 9 | 792
acute quadriplegic myopathy 9 | 1,158
dermatomyositis 9 | 966
juvenile dermatomyositis 9 | 1,187
lung carcinoma 9 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
Seizures 8 | 596
ductal carcinoma in situ 8 | 1,745
pancreatic cancer 8 | 2,398
Cognitive delay 7 | 608
Concave bridge of nose 7 | 195
Cornelia de Lange syndrome 7 | 21
Depressed nasal bridge 7 | 195
Depressed nasal root/bridge 7 | 195
Endometriosis 7 | 540
Global developmental delay 7 | 608
Liver cancer 7 | 604
Mental and motor retardation 7 | 608
Pick disease 7 | 1,894
Short stature 7 | 531
Small head 7 | 374
pituitary cancer 7 | 1,972
primary pancreatic ductal adenocarcinoma 7 | 1,109
ulcerative colitis 7 | 1,819
Anteverted nostril 6 | 191
Parkinson's disease 6 | 392
Short nose 6 | 132
Small nose 6 | 132
Squamous cell carcinoma 6 | 129
non primary Sjogren syndrome sicca 6 | 891
spina bifida 6 | 1,074
Blepharoptosis 5 | 231
Breast Neoplasms 5 | 445
Broad flat nasal bridge 5 | 236
Carcinoma, Hepatocellular 5 | 228
Carcinoma, Squamous Cell 5 | 110
Congenital hypoplasia of penis 5 | 176
Hypoplastic mandible condyle 5 | 275
Liver carcinoma 5 | 240
Mandibular hypoplasia 5 | 275
Micrognathism 5 | 275
Muscle Hypertonia 5 | 88
Nasal bridge wide 5 | 236
Roberts syndrome 5 | 15
Schizophrenia 5 | 1,160
Sensorineural Hearing Loss (disorder) 5 | 284
Short neck 5 | 140
Synophrys 5 | 40
acute myeloid leukemia 5 | 783
atypical teratoid/rhabdoid tumor 5 | 357
cystic fibrosis 5 | 1,696
pancreatic carcinoma 5 | 562
tuberculosis 5 | 2,010
Prostatic Neoplasms 4 | 495
esophageal adenocarcinoma 4 | 737
gastric cancer 4 | 459
gastric carcinoma 4 | 807

Tissue

Blood and immune system 83 | 16,909
Digestive Tract 83 | 17,369
Endocrine System 83 | 18,159
Female tissues 83 | 17,400
Liver and Pancreas 83 | 16,750
Male tissues 83 | 17,142
Nervous System 83 | 16,725
Skin and soft tissues 83 | 17,230
Urinary Tract 83 | 16,678
Cardiovascular System 82 | 15,192
Respiratory system 82 | 16,393

Target Family

Non-IDG 45 | 12,091
Enzyme 13 | 4,145
Transcription Factor 10 | 1,400
Kinase 8 | 634
Epigenetic 7 | 242
TF/Epigenetic 1 | 38

GO Component

chromatin 84 | 84
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Melanoma-associated antigen D1 MAGED1 Tbio Non-IDG -1.55131 46.3 245
PCNA-interacting partner PARPBP Tbio Non-IDG -2.15213 141.3 72
N-acetyltransferase ESCO1 ESCO1 Tbio Enzyme -1.65145 44.6 49
Serine/threonine-protein phosphatase 1 regulatory subunit 10 PPP1R10 Tbio Enzyme -1.71843 50.9 110
Cohesin subunit SA-1 STAG1 Tbio Non-IDG -2.47449 292.2 200
Lysine-specific demethylase 3A KDM3A Tchem Epigenetic -1.83544 74.7 253
SMC5-SMC6 complex localization factor protein 2 SLF2 Tbio Non-IDG -0.68501 3.77 14
Lysine-specific demethylase hairless HR Tbio Enzyme -1.13301 12.4 99
Serine protease HTRA2, mitochondrial HTRA2 Tbio Enzyme -2.60032 392.5 519
Ubiquitin-conjugating enzyme E2 A UBE2A Tbio Non-IDG -1.53597 32.3 117