Development Level

Tbio 99 | 11,651
Tdark 16 | 6,593
Tchem 7 | 1,388
Tclin 2 | 612

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 9 | 979
male infertility 5 | 123
embryonic lethality prior to t... 4 | 278
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
abnormal humerus morphology 3 | 11
embryonic growth retardation 3 | 106
abnormal behavioral response t... 2 | 66
abnormal embryo turning 2 | 31
decreased body length 2 | 101
decreased circulating glucose ... 2 | 126
decreased circulating serum al... 2 | 82
decreased total body fat amoun... 2 | 207
edema 2 | 59
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
increased fasted circulating g... 2 | 76
increased or absent threshold ... 2 | 101
abnormal brain morphology 1 | 13
abnormal cranium morphology 1 | 36
abnormal external female genit... 1 | 1
abnormal external male genital... 1 | 1
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal nail morphology 1 | 8
abnormal ovary morphology 1 | 7
abnormal pancreas morphology 1 | 13
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
abnormal tail movements 1 | 12
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating glycerol... 1 | 16
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
female infertility 1 | 60
hydroencephaly 1 | 14
hydrometra 1 | 53
hyperactivity 1 | 148
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased circulating glycerol... 1 | 9
increased circulating insulin ... 1 | 3
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
prenatal lethality 1 | 28
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
sclerocornea 1 | 2
small superior vagus ganglion 1 | 74
small testis 1 | 58
vertebral fusion 1 | 23

Disease

Carcinoma 91 | 11,493
ovarian cancer 70 | 8,520
osteosarcoma 67 | 7,950
group 3 medulloblastoma 43 | 4,104
psoriasis 38 | 6,694
lung cancer 34 | 4,740
ependymoma 33 | 4,679
glioblastoma 33 | 5,792
medulloblastoma, large-cell 32 | 6,241
Kidney cancer 30 | 2,613
atypical teratoid / rhabdoid tumor 30 | 5,112
Intellectual disability 25 | 1,016
primitive neuroectodermal tumor 25 | 3,035
malignant mesothelioma 24 | 3,232
Breast cancer 23 | 3,578
adult high grade glioma 21 | 3,801
adrenocortical carcinoma 20 | 1,428
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
Autosomal recessive predisposition 19 | 1,442
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
Cognitive delay 16 | 608
Dull intelligence 16 | 645
Global developmental delay 16 | 608
Joubert syndrome 16 | 66
Low intelligence 16 | 645
Mental Retardation 16 | 645
Mental and motor retardation 16 | 608
Mental deficiency 16 | 645
Poor school performance 16 | 645
invasive ductal carcinoma 16 | 2,951
non-small cell lung cancer 15 | 2,890
Microcephaly 14 | 166
Pick disease 14 | 1,894
Polydactyly 14 | 107
posterior fossa group B ependymoma 14 | 416
tuberculosis 14 | 2,010
Astrocytoma, Pilocytic 13 | 3,081
Ciliopathy 13 | 71
lung adenocarcinoma 13 | 2,716
lung carcinoma 13 | 2,843
oligodendroglioma 13 | 2,850
pancreatic cancer 13 | 2,398
Cancer 12 | 2,499
Nephronophthisis 12 | 80
Short stature 12 | 531
Small head 12 | 374
Schizophrenia 11 | 1,160
colon cancer 11 | 1,478
ductal carcinoma in situ 11 | 1,745
Nystagmus 10 | 317
Obesity 10 | 678
astrocytic glioma 10 | 2,597
chronic rhinosinusitis 10 | 512
nasopharyngeal carcinoma 10 | 1,058
ulcerative colitis 10 | 1,819
Congenital hypoplasia of penis 9 | 176
Retinitis Pigmentosa 9 | 226
Rheumatoid arthritis 9 | 1,191
diabetes mellitus 9 | 1,728
tuberculosis and treatment for 6 months 9 | 409
Atopic dermatitis 8 | 952
Bardet-Biedl syndrome 8 | 51
Cerebellar Ataxia 8 | 304
Electroretinogram abnormal 8 | 95
Glaucoma 8 | 239
Meckel syndrome 8 | 46
active Crohn's disease 8 | 922
breast carcinoma 8 | 1,638
pituitary cancer 8 | 1,972
subependymal giant cell astrocytoma 8 | 2,287
Asphyxiating thoracic dystrophy 7 | 44
Cataract 7 | 297
Cystic kidney disease 7 | 26
Epilepsy 7 | 792
MICROCEPHALY, PRIMARY AUTOSOMAL RECESSIVE, 1 7 | 16
Muscle hypotonia 7 | 571
Retinal Degeneration 7 | 106
Seckel syndrome 7 | 34
Seizures 7 | 596
Senior-Loken syndrome 7 | 22
group 4 medulloblastoma 7 | 1,855
interstitial cystitis 7 | 2,312
non primary Sjogren syndrome sicca 7 | 891
Abnormality of retinal pigmentation 6 | 111
Amyotrophic lateral sclerosis 6 | 451
Brachydactyly 6 | 156
Familial aplasia of the vermis 6 | 19
Feeding difficulties in infancy 6 | 175
Hydrolethalus syndrome 6 | 128
Hypertensive disease 6 | 292
Hypogonadism 6 | 173
Increase in blood pressure 6 | 119
Lens Opacities 6 | 231
Retinal pigment epithelial abnormality 6 | 111
Severe mental retardation (I.Q. 20-34) 6 | 99
Sloping forehead 6 | 46
hepatocellular carcinoma 6 | 547
pediatric high grade glioma 6 | 1,064
progressive supranuclear palsy 6 | 676

Tissue

Endocrine System 122 | 18,159
Female tissues 121 | 17,400
Male tissues 121 | 17,142
Skin and soft tissues 121 | 17,230
Blood and immune system 120 | 16,909
Digestive Tract 120 | 17,369
Respiratory system 119 | 16,393
Liver and Pancreas 118 | 16,750
Nervous System 118 | 16,725
Urinary Tract 118 | 16,678
Cardiovascular System 113 | 15,192

Target Family

Non-IDG 105 | 12,091
Enzyme 12 | 4,145
Kinase 6 | 634
Epigenetic 1 | 242

GO Component

centriole 124 | 124
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
Centrosomal protein of 295 kDa CEP295 Tdark Non-IDG -0.40512 3.13 13
Centrosomal protein of 83 kDa CEP83 Tdark Non-IDG -0.47180 2.89 0
Poly [ADP-ribose] polymerase 3 PARP3 Tclin Enzyme -1.66230 41.9 193
Testis-specific serine kinase substrate TSKS Tbio Enzyme -0.99386 9.94 98
Cilia- and flagella-associated protein 20 CFAP20 Tbio Non-IDG -1.78803 43.9 88
Kinesin-like protein KIF3A KIF3A Tbio Non-IDG -2.06068 113.6 153
Protein chibby homolog 1 CBY1 Tbio Non-IDG -2.29880 197.7 79
WASH complex subunit 1 WASHC1 Tbio Non-IDG -0.28297 2.17 4
Centriolar coiled-coil protein of 110 kDa CCP110 Tbio Non-IDG -1.45267 26.4 109