Development Level

Tbio 78 | 10,625
Tdark 16 | 7,003
Tchem 9 | 1,890
Tclin 2 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

abnormal behavior 3 | 226
embryonic lethality prior to t... 3 | 187
preweaning lethality, complete... 3 | 633
abnormal humerus morphology 2 | 11
decreased circulating choleste... 2 | 85
hyperactivity 2 | 108
hypoactivity 2 | 89
increased circulating choleste... 2 | 53
increased or absent threshold ... 2 | 128
preweaning lethality, incomple... 2 | 260
abnormal behavioral response t... 1 | 52
abnormal brain morphology 1 | 6
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal embryo turning 1 | 15
abnormal external female genit... 1 | 1
abnormal external male genital... 1 | 1
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal joint morphology 1 | 14
abnormal nail morphology 1 | 7
abnormal retina morphology 1 | 100
abnormal spleen morphology 1 | 36
abnormal tail morphology 1 | 17
abnormal tail movements 1 | 12
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 14
cardiovascular system phenotyp... 1 | 35
decreased CD4-positive, alpha ... 1 | 19
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased circulating alanine ... 1 | 53
decreased circulating calcium ... 1 | 33
decreased circulating glucose ... 1 | 121
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased grip strength 1 | 123
decreased hematocrit 1 | 25
decreased lactate dehydrogenas... 1 | 14
decreased lean body mass 1 | 195
decreased prepulse inhibition 1 | 52
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
embryonic growth retardation 1 | 28
hydroencephaly 1 | 6
hydrops fetalis 1 | 22
improved glucose tolerance 1 | 56
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating amylase ... 1 | 13
increased circulating chloride... 1 | 43
increased circulating glycerol... 1 | 11
increased circulating insulin ... 1 | 2
increased fasted circulating g... 1 | 68
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased sacral vertebrae num... 1 | 62
male infertility 1 | 62
polydactyly 1 | 22
vertebral fusion 1 | 23

Disease

ovarian cancer 61 | 8,484
osteosarcoma 60 | 7,933
psoriasis 34 | 6,685
glioblastoma 29 | 5,572
medulloblastoma, large-cell 29 | 6,234
lung cancer 28 | 4,466
posterior fossa group B ependymoma 23 | 1,530
group 3 medulloblastoma 22 | 2,254
primitive neuroectodermal tumor 22 | 3,031
atypical teratoid / rhabdoid tumor 20 | 4,369
malignant mesothelioma 20 | 3,162
Breast cancer 19 | 3,094
Carcinoma 19 | 2,147
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,289
pediatric high grade glioma 17 | 2,712
Intellectual disability 15 | 573
Joubert syndrome 15 | 61
adrenocortical carcinoma 15 | 1,427
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,956
invasive ductal carcinoma 14 | 2,950
Microcephaly 13 | 149
Pick disease 13 | 1,893
ependymoma 13 | 2,514
pancreatic cancer 13 | 2,300
pilocytic astrocytoma 13 | 3,086
Nephronophthisis 12 | 74
Cancer 11 | 2,346
Polydactyly 11 | 93
colon cancer 11 | 1,475
lung adenocarcinoma 11 | 2,713
lung carcinoma 11 | 2,844
non-small cell lung cancer 11 | 2,798
oligodendroglioma 11 | 2,849
sonic hedgehog group medulloblastoma 11 | 1,482
ulcerative colitis 11 | 2,087
ductal carcinoma in situ 10 | 1,745
nasopharyngeal carcinoma 10 | 1,056
tuberculosis 10 | 1,557
tuberculosis and treatment for 6 months 10 | 686
astrocytic glioma 9 | 2,241
group 4 medulloblastoma 9 | 1,875
Bardet-Biedl Syndrome 8 | 40
Ciliopathy 8 | 57
Meckel syndrome 8 | 48
chronic rhinosinusitis 8 | 512
Atopic dermatitis 7 | 944
Rheumatoid Arthritis 7 | 1,160
Seckel syndrome 7 | 34
Senior-Loken syndrome 7 | 21
adult high grade glioma 7 | 2,148
breast carcinoma 7 | 1,614
interstitial cystitis 7 | 2,299
non primary Sjogren syndrome sicca 7 | 840
Asphyxiating thoracic dystrophy 6 | 32
Obesity 6 | 616
Schizophrenia 6 | 501
active Crohn's disease 6 | 918
atypical teratoid/rhabdoid tumor 6 | 1,095
diabetes mellitus 6 | 1,663
hepatocellular carcinoma 6 | 532
pituitary cancer 6 | 1,972
posterior fossa group A ependymoma 6 | 1,511
Cystic kidney disease 5 | 25
Orofaciodigital syndrome 5 | 19
Retinitis pigmentosa 5 | 153
aldosterone-producing adenoma 5 | 664
astrocytoma 5 | 1,493
gastric cancer 5 | 430
medulloblastoma 5 | 1,524
progressive supranuclear palsy 5 | 674
subependymal giant cell astrocytoma 5 | 2,287
Endometriosis 4 | 535
Fundus dystrophy 4 | 77
Hydrolethalus syndrome 4 | 128
Leber congenital amaurosis 4 | 72
Renal dysplasia and retinal aplasia (disorder) 4 | 10
Waldenstrons macroglobulinemia 4 | 765
dermatomyositis 4 | 933
pancreatic carcinoma 4 | 567
primary pancreatic ductal adenocarcinoma 4 | 1,271
Alzheimer's disease 3 | 644
Amyotrophic Lateral Sclerosis 3 | 431
Huntington's disease 3 | 72
Hydrocephalus 3 | 60
IGA Glomerulonephritis 3 | 454
Male infertility 3 | 170
Mammary Neoplasms 3 | 410
Mammary Neoplasms, Experimental 3 | 150
Multiple myeloma 3 | 1,327
Neurodegenerative disease 3 | 383
Paraplegia 3 | 71
Parkinson's disease 3 | 364
Polycystic Ovary Syndrome 3 | 332
Primary ciliary dyskinesia 3 | 73
Prostate cancer 3 | 172
Renal Cell Carcinoma 3 | 199
Retinal Degeneration 3 | 49
periodontitis 3 | 269
primary Sjogren syndrome 3 | 789

Tissue

Digestive Tract 103 | 18,473
Endocrine System 103 | 18,512
Liver and Pancreas 103 | 18,136
Male tissues 103 | 17,969
Urinary Tract 103 | 18,444
Blood and immune system 102 | 17,995
Cardiovascular System 102 | 17,958
Female tissues 102 | 18,647
Nervous System 102 | 18,561
Respiratory system 102 | 17,484
Skin and soft tissues 102 | 18,115

Target Family

Non-IDG 87 | 11,971
Enzyme 11 | 4,146
Kinase 6 | 634
Epigenetic 1 | 242

GO Component

centriole 105 | 105
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Centrosomal protein of 164 kDa CEP164 Tbio Non-IDG -0.96655 10.2 84
Coiled-coil domain-containing protein 92 CCDC92 Tdark Non-IDG 0.08 0.73 76
Centrosomal protein of 290 kDa CEP290 Tbio Non-IDG -1.97186 101.3 125
Centrosomal protein of 152 kDa CEP152 Tbio Non-IDG -1.23739 18.0 90
Coiled-coil domain-containing protein 146 CCDC146 Tdark Non-IDG 0.90 0.11 67
GTP-binding nuclear protein Ran RAN Tbio Enzyme -2.52041 303.8 437
Tubulin gamma-1 chain TUBG1 Tbio Non-IDG -1.30625 20.5 277
Protein NEDD1 NEDD1 Tbio Non-IDG -1.42176 27.4 149
Heat shock 70 kDa protein 1B HSPA1B Tbio Non-IDG -1.59467 0.00000 58
Centrosomal protein of 128 kDa CEP128 Tdark Non-IDG 0.80 0.10 70